Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Patricia Gonnella"'
Autor:
Guang-Xian Zhang, Kedar R Mahajan, Elisabeth R. Mari, Thomas Leist, Jaime Imitola, Patricia Gonnella, Daniel Hwang, Javad Rasouli, Farinaz Safavi, Bogoljub Ciric, Abdolmohamad Rostami
Publikováno v:
The Journal of Immunology. 194:5085-5093
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). Studies in animal models of MS have shown that granulocyte-macrophage colony-stimulating factor (GM-CSF) produced by T cells is necessary for development of autoimm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0245656ad3c6053fa0e9baff536391
https://doi.org/10.4049/jimmunol.1403243
https://doi.org/10.4049/jimmunol.1403243
Autor:
Farinaz Safavi, Hongmei Li, Guang Xian Zhang, Abdolmohamad Rostami, Elisabeth R. Mari, Javad Rasouli, Patricia Gonnella
Publikováno v:
Immunologic Research. 61:294-302
c-kit (CD117) is a tyrosine kinase receptor found in various types of immune cells. It has been shown that c-kit plays a role in the pathogenesis of multiple sclerosis, an inflammatory demyelinating disorder of the CNS. Recent data have suggested an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aeb9fcb2a860ad00f3b8ec736f0fa9
https://doi.org/10.1007/s12026-015-8624-6
https://doi.org/10.1007/s12026-015-8624-6
Autor:
Tonio Pera, Patricia Gonnella, Radhika Joshi, Gloria S. Forkuo, Brian J. Knoll, Sergio Parra, Hosu Kim, Vaidehi J. Thanawala, Raymond B. Penn, Daniel Valdez, Nour A. Al-Sawalha, Richard A. Bond, Julia K. L. Walker
Mice lacking the endogenous β2-adrenoceptor (β2AR) agonist epinephrine (phenylethanolamine N-methyltransferase [PNMT]-knockout mice) are resistant to developing an "asthma-like" phenotype in an ovalbumin sensitization and challenge (Ova S/C) model,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e9a4932f7d2cff6c9abd872692aac2
https://europepmc.org/articles/PMC4979368/
https://europepmc.org/articles/PMC4979368/
Autor:
Melissa Cullimore, Fang Zhou, Bogoljub Ciric, Abdolmohamad Rostami, Hongmei Li, Yaping Yan, Elisabetta Lauretti, Ke Li, Patricia Gonnella, Guang Xian Zhang
Publikováno v:
European Journal of Immunology. 42:1449-1458
Interleukin-10 (IL-10) is an anti-inflammatory cytokine that plays an important role in regulating the local inflammatory immune response, but regulatory mechanisms of this cytokine have not been fully elucidated. Here, we demonstrate that IL-10 defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771be63e31d3feaaa950bac7feca0749
https://doi.org/10.1002/eji.201141733
https://doi.org/10.1002/eji.201141733
Autor:
Michael J. Menconi, Bozena Antoniu, Per-Olof Hasselgren, Qin Zhang, Kiyoshi Itagaki, Carl J. Hauser, David I. Soybel, Patricia Gonnella
Publikováno v:
American Journal of Physiology-Cell Physiology. 298:C1127-C1139
Muscle wasting in various catabolic conditions is at least in part regulated by glucocorticoids. Increased calcium levels have been reported in atrophying muscle. Mechanisms regulating calcium homeostasis in muscle wasting, in particular the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ce8e701236cacf6f3980141dbc6949
https://doi.org/10.1152/ajpcell.00309.2009
https://doi.org/10.1152/ajpcell.00309.2009
Autor:
Abdolmohamad Rostami, Guang Xian Zhang, Farinaz Safavi, Ghazal Vessal, Hongmei Li, Bardia Nourbakhsh, Patricia Gonnella, Fang Zhou
Zymosan has previously been reported to have both pro-inflammatory and anti-inflammatory effects. Here we demonstrate that low dose zymosan prevented or reversed chronic and relapsing paralysis in EAE. In suppressing CNS autoimmune inflammation, zymo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7195c98f0835a028dd2dbf6ad8f8a81a
https://europepmc.org/articles/PMC3534935/
https://europepmc.org/articles/PMC3534935/
Autor:
Ira J. Smith, Nima Alamdari, Zaira Aversa, Per-Olof Hasselgren, Steven Tizio, Patricia Gonnella
Publikováno v:
Current opinion in clinical nutrition and metabolic care. 13(4)
The purpose of this review is to discuss novel insight into mechanisms of glucocorticoid-regulated muscle wasting, in particular the role of transcription factors and nuclear cofactors. In addition, novel strategies that may become useful in the trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabc20e0144a438e82a78930beb28e91
https://pubmed.ncbi.nlm.nih.gov/20473154
https://pubmed.ncbi.nlm.nih.gov/20473154
Autor:
Zaira Aversa, Nima Alamdari, Patricia Gonnella, Ira J. Smith, Patrick O'Neal, Per-Olof Hasselgren
Publikováno v:
The international journal of biochemistrycell biology. 42(5)
Sepsis-induced muscle wasting has severe clinical consequences, including muscle weakness, need for prolonged ventilatory support and stay in the intensive care unit, and delayed ambulation with risk for pulmonary and thromboembolic complications. Un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44194c2a7359a6b75a4cc4557099b4b
https://pubmed.ncbi.nlm.nih.gov/20079455
https://pubmed.ncbi.nlm.nih.gov/20079455
Autor:
Per-Olof Hasselgren, Stewart H. Lecker, Patricia Gonnella, Victoria Petkova, Michael J. Menconi
Publikováno v:
Journal of cellular biochemistry. 105(2)
Dexamethasone-treated L6 (a rat cell line) and C2C12 (a mouse cell line) myotubes are frequently used as in vitro models of muscle wasting. We compared the effects of different concentrations of dexamethasone and corticosterone (the naturally occurri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac2ad85aaba9289ea538fd64d5abde3
https://pubmed.ncbi.nlm.nih.gov/18615595
https://pubmed.ncbi.nlm.nih.gov/18615595
Publikováno v:
Scopus-Elsevier
Calcitonin gene-related peptide (CGRP) is widely distributed in the gastrointestinal nerves, including those of the esophagus. The present investigation was undertaken to examine the effect and the mechanism of action of CGRP on the lower esophageal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a568f62cedbbf13e46ebef04c6e431b8
https://pubmed.ncbi.nlm.nih.gov/3257196
https://pubmed.ncbi.nlm.nih.gov/3257196