Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress

Autor: Laura Martinez-Ruiz, Javier Florido, César Rodriguez-Santana, Alba López-Rodríguez, Ana Guerra-Librero, Beatriz I. Fernández-Gil, Patricia García-Tárraga, José Manuel Garcia-Verdugo, Felix Oppel, Holger Sudhoff, David Sánchez-Porras, Amadeo Ten-Steve, José Fernández-Martínez, Pilar González-García, Iryna Rusanova, Darío Acuña-Castroviejo, Víctor Carriel, Germaine Escames

Publikováno v: Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115518- (2023)

Head and neck squamous cell carcinoma present a high mortality rate. Melatonin has been shown to have oncostatic effects in different types of cancers. However, inconsistent results have been reported for in vivo applications. Consequently, an altern

Externí odkaz: https://doaj.org/article/88cf62c5f1de4102ac70780b346f856d

Ultrastructural Characterization of Human Oligodendrocytes and Their Progenitor Cells by Pre-embedding Immunogold

Autor: María J. Ulloa-Navas, Pedro Pérez-Borredá, Raquel Morales-Gallel, Ana Saurí-Tamarit, Patricia García-Tárraga, Antonio J. Gutiérrez-Martín, Vicente Herranz-Pérez, Josée M. García-Verdugo

Publikováno v: Frontiers in Neuroanatomy, Vol 15 (2021)

Oligodendrocytes are the myelinating cells of the central nervous system. They provide trophic, metabolic, and structural support to neurons. In several pathologies such as multiple sclerosis (MS), these cells are severely affected and fail to remyel

Externí odkaz: https://doaj.org/article/35c419ed6f3b4c0eb4d25223a9601ded

Tyramide Signal Amplification for Immunoelectron Microscopy

Autor: Vicente Herranz-Pérez, José Manuel García-Verdugo, Patricia García-Tárraga, Susana González-Granero, Pedro Pérez-Borredá, María José Ulloa-Navas

Publikováno v: Neuromethods ISBN: 9781071615218

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5485797a591de92ae931de7684f27ef7
https://doi.org/10.1007/978-1-0716-1522-5_16

Immunogold Labeling to Detect Streptococcus pyogenes Cas9 in Cell Culture and Tissues by Electron Microscopy

Autor: Patricia García-Tárraga, José Manuel García-Verdugo, María José Ulloa-Navas, Vicente Herranz-Pérez

Publikováno v: Repositori Universitat Jaume I
Universitat Jaume I

Final publication is available from Mary Ann Liebert, Inc., publishers https://doi.org/10.1089/crispr.2019.0032. The CRISPR-Cas9 system is a powerful and yet precise DNA-editing tool in rapid development. By combining immunogold labeling and electron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e05cd625691f4589c768544ce81d7e1
http://hdl.handle.net/10234/187133

Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina

Autor: Ma Dolores Sequedo, Elena Aller, Patricia García-Tárraga, Cristina Martinez-Fernandez de la Camara, José Manuel García-Verdugo, Teresa Jaijo, José M. Millán, Ulises Gómez-Pinedo, Regina Rodrigo

Publikováno v: Martínez-Fernández de la Cámara, Cristina Sequedo, María Dolores Gómez-Pinedo, Ulises Jaijo, Teresa Aller, Elena García Tárraga, Patricia García Verdugo, José Manuel Millán, José María Rodrigo, Regina 2013 Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina. Experimental Eye Research 9 111 122 133
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

nherited retinal degenerations affecting both rod and cone photoreceptors constitute one of the causes 74 of incurable blindness in the developed world. Cyclic guanosine monophosphate (cGMP) is crucial in the 75 phototransduction and, mutations in ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dec7f044feba70fc1db83a88c962c3
http://hdl.handle.net/10550/32581