Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Patricia G. Spear"'
Autor:
Patricia G, Spear
Publikováno v:
Annual Review of Virology. 9:1-17
My grandparents were immigrants. My paternal grandfather was illiterate. Yet my parents were able to complete college and to become teachers. I had a conventional upbringing in a small town in Florida, graduating from high school in 1960. I was fortu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5cea91d520e5dbcac7b5010c5b770e
https://doi.org/10.1146/annurev-virology-100520-012840
https://doi.org/10.1146/annurev-virology-100520-012840
Autor:
Miri Yoon, Sarah J Kopp, Joann M Taylor, Christopher S Storti, Patricia G Spear, William J Muller
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16122 (2011)
Herpes virus entry mediator (HVEM) is one of two principal receptors mediating herpes simplex virus (HSV) entry into murine and human cells. It functions naturally as an immune signaling co-receptor, and may participate in enhancing or repressing imm
Externí odkaz:
https://doaj.org/article/23910ad33fc947a78e2c4973d531b3d3
Publikováno v:
Virus Research. 171:227-230
Among the herpesvirus glycoprotein B (gB) fusion proteins, the hydrophobic content of fusion loops and membrane proximal regions (MPRs) are inversely correlated with each other. We examined the functional importance of the hydrophobicity of these reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a742d713a5a7d46e0e537f8a60658ba
https://doi.org/10.1016/j.virusres.2012.10.015
https://doi.org/10.1016/j.virusres.2012.10.015
Autor:
Patricia G. Spear, Pavel Osten, Kelly E. Glajch, Ulrike E. Maurer, Ghazal Banisadr, Sarah J. Kopp, Kay Grünewald, Richard J. Miller
Multiple entry receptors can mediate infection of cells by herpes simplex virus (HSV), permitting alternative pathways for infection and disease. We investigated the roles of two known entry receptors, herpesvirus entry mediator (HVEM) and nectin-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9297c6fd07b120e4298d138dd4e28702
https://ora.ox.ac.uk/objects/uuid:6f737e09-e512-418c-92e3-eb6fc794d382
https://ora.ox.ac.uk/objects/uuid:6f737e09-e512-418c-92e3-eb6fc794d382
Autor:
Mitchell Kronenberg, Timothy C. Cheung, Matthew G. Macauley, Hideki Sanjo, Klaus Pfeffer, Lisa M. Oborne, Paula S. Norris, Kenneth M. Murphy, Claire D'Souza, Carl F. Ware, Satoshi Fukuyama, Patricia G. Spear, Marcos W. Steinberg
Publikováno v:
The Journal of Immunology. 183:7286-7296
The inhibitory cosignaling pathway formed between the TNF receptor herpesvirus entry mediator (HVEM, TNFRSF14) and the Ig superfamily members, B and T lymphocyte attenuator (BTLA) and CD160, limits the activation of T cells. However, BTLA and CD160 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893e2f0a14b7ab3e87949b9815e0f13e
https://doi.org/10.4049/jimmunol.0902490
https://doi.org/10.4049/jimmunol.0902490
Publikováno v:
Journal of Virology. 83:11607-11615
Glycoprotein L (gL) is one of four glycoproteins required for the entry of herpes simplex virus (HSV) into cells and for virus-induced cell fusion. This glycoprotein oligomerizes with gH to form a membrane-bound heterodimer but can be secreted when e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563ab3b621eb8c4866928fc750a6e2df
https://doi.org/10.1128/jvi.01369-09
https://doi.org/10.1128/jvi.01369-09
Autor:
Marcos W. Steinberg, Satoshi Fukuyama, Klaus Pfeffer, Patricia G. Spear, Hideki Sanjo, Matthew G. Macauley, Paula S. Norris, Kenneth M. Murphy, Timothy C. Cheung, Claire D'Souza, Carl F. Ware, Mitchell Kronenberg, Lisa M. Oborne
Publikováno v:
Proceedings of the National Academy of Sciences. 106:6244-6249
The herpesvirus entry mediator (HVEM; TNFRSF14) activates NF-κB through the canonical TNF-related cytokine LIGHT, serving as a costimulatory pathway during activation of T cells. HVEM also functions as a ligand for the Ig superfamily members B and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23951789a044b0cffc8647576792a8f9
https://doi.org/10.1073/pnas.0902115106
https://doi.org/10.1073/pnas.0902115106
Publikováno v:
Future Virology. 2:509-517
Herpes simplex virus (HSV) infections are highly prevalent in human populations. Clinical manifestations are often not apparent or are limited to mucocutaneous lesions, at least in persons other than neonates or the immunocompromised. The virus estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a11f369f72ae50eb02db50e889f652a6
https://doi.org/10.2217/17460794.2.5.509
https://doi.org/10.2217/17460794.2.5.509
Autor:
Erick Lin, Anna Zago, Miri Yoon, Klaus Pfeffer, Nanette Susmarski, Carl F. Ware, Patricia G. Spear, Yoshimi Takai, Jun Miyoshi, Joann M. Taylor
Publikováno v:
Cell Host & Microbe. 2(1):19-28
SummaryEither herpesvirus entry mediator (HVEM, TNFRSF14) or nectin-1 (PVRL1) is sufficient for herpes simplex virus (HSV) infection of cultured cells. The contribution of individual receptors to infection in vivo and to disease is less clear. To ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fdfebb931092fac0221431c641b7a5