Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patricia G. Schneider"'
Publikováno v:
Regulatory Peptides. 163:37-42
Neurotensin (NT) is a tridecapeptide distributed in central and peripheral nervous systems, which can behave as a neurotransmitter or neuromodulator at central and peripheral levels. Herein we tested the potential effect of this peptide on quinuclidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d935785bd6717b9b973ebe9a7e50d67
https://doi.org/10.1016/j.regpep.2010.04.002
https://doi.org/10.1016/j.regpep.2010.04.002
Publikováno v:
Neurochemical Research. 25:637-643
The administration of convulsant drugs has proven a powerful tool to study experimental epilepsy. We have already reported that the administration of convulsant 3-mercaptopropionic acid (mp) at 150 mg/kg enhances binding affinity of muscarinic antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e40a14a476d127bee2d696d6e74b1e
https://doi.org/10.1023/a:1007507019191
https://doi.org/10.1023/a:1007507019191
Publikováno v:
Neurochemical Research. 24:1417-1422
Two brain soluble fractions, named peaks I and II, which respectively stimulate and inhibit neuronal Na+, K+-ATPase activity, have been isolated by gel filtration in Sephadex G-50. Since cholinergic transmission seems related to such enzyme activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8789e7dd34c8e691f060020ee4f04893
https://doi.org/10.1023/a:1022536824190
https://doi.org/10.1023/a:1022536824190
Publikováno v:
Molecular and Chemical Neuropathology. 32:213-221
It has already been shown that the administration of convulsant 3-mercaptopropionic acid at 150 mg/kg enhances binding affinity of muscarinic antagonist [3H]quinuclidinyl benzilate ([3H]QNB) to certain rat CNS membranes without affecting site number.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadbdc02253b947d0c1a6426b46e95d7
https://doi.org/10.1007/bf02815177
https://doi.org/10.1007/bf02815177
Publikováno v:
Neurochemistry international. 62(3)
The cholinergic system has been implicated in several experimental epilepsy models. In a previous study bicuculline (BIC), known to antagonize GABA-A postsynaptic receptor subtype, was administered to rats at subconvulsant (1 mg/kg) and convulsant (7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cff405ad1207e29e30b4d6225a0a2a
https://pubmed.ncbi.nlm.nih.gov/23279735
https://pubmed.ncbi.nlm.nih.gov/23279735
Publikováno v:
Molecular and Chemical Neuropathology. 21:13-22
Acetylcholinesterase activity (AChE) was assayed in rat CNS membrane fractions after administration of the convulsant 3-mercaptopropionic acid (150 mg/kg, ip). In comparison with saline-injected controls, total AChE activity decreased 12–20% in str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c717a95083837188f3d99c5385147dc
https://doi.org/10.1007/bf03160081
https://doi.org/10.1007/bf03160081
Publikováno v:
Neurochemistry international. 20(4)
It is known that quinuclidinyl benzilate (QNB) binds specifically and with high affinity to the cholinergic muscarinic receptor and that behaves as a potent antagonist of this receptor. We have analysed l -[3H]QNB binding to rat CNS membranes after t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c2faeb528dbede2e1e5da660b7a0d9
https://pubmed.ncbi.nlm.nih.gov/1304874
https://pubmed.ncbi.nlm.nih.gov/1304874