Tridimensional mapping of Phox2b expressing neurons in the brainstem of adultMacaca fascicularisand identification of the retrotrapezoid nucleus

Autor: Clément Bouvier, Jean-François Brunet, Caroline Jan, François Giuliano, Jonathan I. Levy, Patricia Facchinetti, Melyna Achour, Thierry Delzescaux

Publikováno v: Journal of Comparative Neurology. 527:2875-2884

Chemosensitivity is a key mechanism for the regulation of breathing in vertebrates. The retrotrapezoid nucleus is a crucial hub for respiratory chemoreception within the brainstem. It integrates chemosensory information that are both peripheral from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61105b630119f4bb54e1d8530312afea
https://doi.org/10.1002/cne.24713

Human spinal ejaculation generator

Autor: J M Soler, François Giuliano, Pierre Clément, Patricia Facchinetti, Fabrice Chrétien, Clément Chéhensse, Pierre Denys, J. Bernabé, Philippe Andrey, Stéphane Bahrami

Publikováno v: Annals of Neurology. 81:35-45

OBJECTIVE: A spinal ejaculation generator (SEG) has been identified in the rat with lumbar galaninergic interneurons playing a pivotal role (Science 2002;297:1566-1569). The aim was to evidence a SEG in humans. METHODS: Spatial distribution of galani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::368c83c477c8079f34b6404c737f5f2d
https://doi.org/10.1002/ana.24819

PAT1 induces cell death signal and SET mislocalization into the cytoplasm by increasing APP/APLP2 at the cell surface

Autor: Bernadette Allinquant, Stéphanie Briand, Sanjay W. Pimplikar, Alexandra Madeira, Patricia Facchinetti, Jean Michel Pommet, Christine Clamagirand

Publikováno v: Neurobiology of Aging. 32:1099-1113

The cleavage of amyloid precursor protein (APP) by caspases unmasks a domain extending from membrane to caspase cleavage site. This domain induces apoptosis in vitro and in vivo when overexpressed in neurons through the help of an internalization vec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3690e044fc95e8776b8eac4e650c7b94
https://doi.org/10.1016/j.neurobiolaging.2009.05.021

SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients

Autor: Patricia Facchinetti, Emilie Dorard, Bernadette Allinquant, Nicole Déglon, Marie-Claude Gaillard, Chantal Guihenneuc-Jouyaux, Emmanuel Brouillet, Vincent Contremoulins, Véronique Sazdovitch, Charles Duyckaerts

Publikováno v: Neurobiol Aging
Neurobiol Aging, 2014, 35 (5), pp.958-68. ⟨10.1016/j.neurobiolaging.2013.08.039⟩
Neurobiol Aging, 2014, 35 (5), pp.958-68. 〈10.1016/j.neurobiolaging.2013.08.039〉

International audience; Caspase cleaved amyloid precursor protein (APPcc) and SET are increased and mislocalized in the neuronal cytoplasm in Alzheimer Disease (AD) brains. Translocated SET to the cytoplasm can induce tau hyperphosphorylation. To elu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f03f451100d7af73ce836b01fc1ddff
https://hal.archives-ouvertes.fr/hal-00946234

M-cadherin Distribution in the Mouse Adult Neuromuscular System Suggests a Role in Muscle Innervation

Autor: François Rieger, Marc Nicolet, Françoise Padilla, Danièle Goudou, Carmen Cifuentes-Diaz, Patricia Facchinetti, René-Marc Mège

Publikováno v: European Journal of Neuroscience. 8:1666-1676

M-cadherin belongs to the Ca(2+)-dependent cadherin family of cell adhesion molecules and was first isolated from a mouse muscle cell line cDNA library. It is specifically expressed in muscle tissue during development and is supposed to play an impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119b0212faee766da117f4c690f07d86
https://doi.org/10.1111/j.1460-9568.1996.tb01310.x