Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Patricia DeMarais"'
Publikováno v:
IDCases, Vol 20, Iss , Pp e00812- (2020)
Cutaneous blastomycosis is the most common extrapulmonary manifestation of disseminated blastomycosis, a disease caused by Blastomyces dermatitidis, a dimorphic fungus endemic of North America. Initially, the organism enters the respiratory system by
Externí odkaz:
https://doaj.org/article/6fbba902bcb74caaade5f824c56423a8
Autor:
Ece A Mutlu, Ali Keshavarzian, John Losurdo, Garth Swanson, Basile Siewe, Christopher Forsyth, Audrey French, Patricia Demarais, Yan Sun, Lars Koenig, Stephen Cox, Phillip Engen, Prachi Chakradeo, Rawan Abbasi, Annika Gorenz, Charles Burns, Alan Landay
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003829 (2014)
HIV progression is characterized by immune activation and microbial translocation. One factor that may be contributing to HIV progression could be a dysbiotic microbiome. We therefore hypothesized that the GI mucosal microbiome is altered in HIV pati
Externí odkaz:
https://doaj.org/article/b278e4d3aab749f084c6a546c9f3fe8e
Autor:
Blake Max, Patricia DeMarais
Publikováno v:
International Journal of STD & AIDS. 32:92-95
HIV integrase strand transfer inhibitors (INSTI) are considered well tolerated with few treatment-limiting adverse effects. However, emerging data from clinical trials has identified excessive weight gain possibly due to INSTI alone or with tenofovir
Publikováno v:
Infectious Diseases and Therapy, Vol 9, Iss 3, Pp 691-696 (2020)
Infectious Diseases and Therapy
Infectious Diseases and Therapy
A potential drug-drug interaction exists between divalent and trivalent cations (Ca2+, Fe3+, Mg2+, Al3+, Zn2+) and HIV-1 integrase strand transfer inhibitors (INSTIs). There are limited case reports describing the clinical significance of this potent
Publikováno v:
Journal of AIDS and HIV Treatment. 2
Publikováno v:
IDCases
IDCases, Vol 20, Iss, Pp e00812-(2020)
IDCases, Vol 20, Iss, Pp e00812-(2020)
Highlights • -Blastomycosis is a chronic granulomatous disease that usually starts as a pulmonary infection. • -A high percentage of patients will develop a disseminated disease if the initial lung infection is left untreated. • -Cutaneous blas
Publikováno v:
Open Forum Infectious Diseases
Background Neurocysticercosis is a major cause of adult-onset epilepsy and premature death in adults. We aimed to describe the clinical and demographic features in a large patient population in Chicago of which published data is limited. Methods A re
Publikováno v:
Open Forum Infectious Diseases
Background Neurocysticercosis is a Neglected Tropical Disease and an important public health issue. Our goal was to collect and analyze data regarding clinically significant gender differences among our Neurocysticercosis patients. Methods A retrospe
Autor:
Basile Siewe, John Losurdo, Audrey L. French, Ece Mutlu, Patricia Demarais, Alan L. Landay, Phillip A. Engen, Christopher B. Forsyth, Shohreh Raeisi, Robin M. Voigt, Garth Swanson, Ali Keshavarzian
Publikováno v:
AIDS. 29:537-546
OBJECTIVE Despite the use of HAART to control HIV, systemic immune activation and inflammation persists with the consequence of developing serious non-AIDS events. The mechanisms that contribute to persistent systemic immune activation have not been
Autor:
Alan L. Landay, Patricia Demarais, Audrey L. French, Nazia Kazmi, Ali Keshavarzian, Jeffrey Martinson, Basile Siewe, Jack T. Stapleton
Publikováno v:
Journal of Leukocyte Biology. 93:811-818
A role for regulatory B cells is shown in HIV-pathogenesis, potentially impacting HIV cell-mediated control. HIV infection is associated with elevated expression of IL-10 and PD-L1, contributing to impairment of T cell effector functions. In autoimmu