Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Patricia D. Kroboth"'
Autor:
William D. Figg, Patricia D. Kroboth, Marilyn K. Speedie, Howard L. McLeod, Daren L. Knoell, Palmer Taylor, Richard T. Okita, Cindy H. Chau, Jordan L. Cohen, Mary Anne Koda-Kimble, Robert A. Blouin, Michael D. Reed, Peter C. Preusch, Timothy S. Tracy, Kenneth W. Miller, Kathy Giacomini, John A. Pieper
Publikováno v:
Pharmacotherapy. 28:821-833
To address the shortage of research-trained pharmaceutical scientists (or doctor of pharmacy [Pharm.D.] scientists), a 2-day pharmacy research conference titled "Pharm.D. Pathways to Biomedical Research" was convened on December 13-14, 2006, at the N
Autor:
David Schwartzman, Michael R. Ujhelyi, Tanya J. Fabian, Sharon E. Corey, Patricia D. Kroboth, Bruce G. Pollock, Kristin L. Bigos
Publikováno v:
Journal of Cardiovascular Electrophysiology. 17:391-395
Decreasing Pain and Anxiety Associated with Atrial Shock. introduction: Implantable atrial defibrillators (IADs) have proved to be safe and effective in the management of atrial fibrillation. A potential limitation of self-activated IAD therapy is pa
Publikováno v:
Physiological Genomics. 17:300-306
Genetic influences and endurance exercise have been shown to alter circulating concentrations of dehydroepiandrosterone (DHEA) and its sulfated conjugate, DHEAS. We hypothesized that acute resistance exercise (RE) and training (RET) would increase DH
Autor:
Frank J. Kroboth, Reginald F. Frye, Janet A. Amico, Patricia D. Kroboth, Charles Hakala, Maggie Folan, Tanya J. Fabian, Roslyn A. Stone, Kristin L. Bigos, Bruce G. Pollock, Ana M. Linares
Publikováno v:
Journal of Clinical Psychopharmacology. 23:96-99
DHEA is marketed and readily available as a daily nutritional supplement to counteract the effects of aging. The effect of DHEA administration on 24-hour plasma cortisol profiles has not been investigated. In this single-blind placebo-controlled cros
Autor:
John Wilson, Reginald F. Frye, Janet A. Amico, Diego Chaves-Gnecco, Jang‐Ik Lee, Patricia D. Kroboth
Publikováno v:
Clinical Pharmacology & Therapeutics. 72:718-728
Objectives Determination of hepatic and intestinal cytochrome P450 (CYP) 3A activity is important, because CYP3A substrates show substantial variability in plasma concentrations as a result of variations in both hepatic and intestinal metabolism. The
Publikováno v:
The American Journal of Geriatric Psychiatry. 10:696-705
Objective The authors examine the usefulness of population pharmacokinetics coupled with electronic compliance monitoring in evaluating consistency of exposure to pharmacotherapy. Adherence to pharmacotherapy can have a significant impact on drug res
Publikováno v:
The American Statistician. 56:273-283
Recently, there has been a lot of effort in the scientific community to understand the role of the naturally occurring hormone, dehydroepiandrosterone (DHEA). In order to plan experiments optimally, it is critical first to characterize the diurnal rh
Autor:
Ana M. Linares, Roslyn A. Stone, Bruce G. Pollock, Maggie Folan, Charles Hakala, Frank J. Kroboth, Reginald F. Frye, Patricia D. Kroboth, Firoozeh S. Salek
Publikováno v:
The Journal of Clinical Pharmacology. 40:596-605
The pharmacokinetics of exogenously administered DHEA have not been well characterized despite its increasing use in therapeutic and research investigations. The purpose of this study was to evaluate the pharmacokinetics of DHEA and its sulfated meta
Publikováno v:
Journal of Clinical Psychopharmacology. 19:114-124
The gamma-aminobutyric acid (GABA) agonist alprazolam is known to decrease adrenocorticotropic hormone and cortisol concentrations. Dehydroepiandrosterone (DHEA) is secreted synchronously with cortisol by the adrenal glands and demonstrates diurnal v
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 716:19-26
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) are endogenous steroids that have recently been widely publicized as potential treatments for many disorders. This paper describes a gas chromatographic-ion trap mass spectropho