Zobrazeno 1 - 10 of 81 pro vyhledávání: '"Patricia Coutinho"'
1
Akademický článek
PFKFB3-mediated Pro-glycolytic Shift in Hepatocellular Carcinoma ProliferationSummary
Autor: Qianhui Dou, Aaron K. Grant, Cody Callahan, Patricia Coutinho de Souza, David Mwin, Adam L. Booth, Imad Nasser, Marwan Moussa, Muneeb Ahmed, Leo L. Tsai
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 61-75 (2023)
Background & Aims: Metabolic reprogramming, in particular, glycolytic regulation, supports abnormal survival and growth of hepatocellular carcinoma (HCC) and could serve as a therapeutic target. In this study, we sought to identify glycolytic regulat
Externí odkaz: https://doaj.org/article/621220d3d4204af9be15d9cace9d473e
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3
Akademický článek
OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth
Autor: Rheal A. Towner, Nataliya Smith, Debra Saunders, Chase A. Brown, Xue Cai, Jadith Ziegler, Samantha Mallory, Mikhail G. Dozmorov, Patricia Coutinho De Souza, Graham Wiley, Kyeongsoon Kim, Shinwook Kang, Doo-Sik Kong, Young-Tae Kim, Kar-Ming Fung, Jonathan D. Wren, James Battiste
Publikováno v: Translational Oncology, Vol 12, Iss 2, Pp 320-335 (2019)
Treatment of glioblastoma (GBM) remains a challenge using conventional chemotherapy, such as temozolomide (TMZ), and is often ineffective as a result of drug resistance. We have assessed a novel nitrone-based agent, OKN-007, and found it to be effect
Externí odkaz: https://doaj.org/article/4089f44b27f847388503665fcdd539a8
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5
Akademický článek
Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts.
Autor: Patricia Coutinho de Souza, Samantha Mallory, Nataliya Smith, Debra Saunders, Xiao-Nan Li, Rene Y McNall-Knapp, Kar-Ming Fung, Rheal A Towner
Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0134276 (2015)
Pediatric glioblastomas (pGBM), although rare, are one of the leading causes of cancer-related deaths in children, with tumors essentially refractory to existing treatments. Here, we describe the use of conventional and advanced in vivo magnetic reso
Externí odkaz: https://doaj.org/article/f08b76a99c3c48f08b4f959fc2603b96
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6
Dissertation/ Thesis
Imunoexpressões pulmonar e esplênica das citocinas IL-12, TGF-β e TNF-α e das proteínas Lisozima e S-100 em Pontoporia blainvillei (Gervais e d\'Orbigny, 1844) (Mammalia, Cetacea)
Autor: Patricia Coutinho de Souza
Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Compreender a função das diferentes proteínas e citocinas durante a vigência de alterações inflamatórias pode contribuir para um melhor conhecimento do sistema imunológico dos mamíferos marinhos e sua relação com os processos patológicos.
Externí odkaz: http://www.teses.usp.br/teses/disponiveis/10/10133/tde-03082010-115416/
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7
Escalas Epworth y Pittsburgh: Un análisis del sueño en los estudiantes de medicina de Cobija-UNITEPC
Autor: Guilherme Vilela Castro, Patricia Coutinho Da Cunha, Renato Alfeu Vilela Castro, David Medrano Choquehuanca
Publikováno v: Revista Científica de Salud de la Amazonia UNITEPC. 1:21-29
Introducción: El sueño es una función fisiológica esencial para la salud física y mental de un ser humano, el horario, la duración y calidad conforman aspectos trascendentales para que un individuo pueda mantenerse física y mentalmente saludab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5488c7f37c8f1d41b8269536fb41c72e
https://doi.org/10.36716/revista-salud-amazonia.v1i2.135
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8
Akademický článek
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9
In vivo detection of distal tumor glycolytic flux stimulated by hepatic ablation in a breast cancer model using hyperpolarized 13C MRI
Autor: Patricia Coutinho de Souza, David Mwin, Aaron K. Grant, Leo L. Tsai, J. Scott Goodwin, Svayam Dialani, Zheng Zhang, Muneeb Ahmed, John T. Moon
Publikováno v: Magnetic Resonance Imaging. 80:90-97
Purpose Hepatic thermal ablation therapy can result in c-Met-mediated off-target stimulation of distal tumor growth. The purpose of this study was to determine if a similar effect on tumor metabolism could be detected in vivo with hyperpolarized 13C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a74933d6ea5517e4fad785cdc7c7080
https://doi.org/10.1016/j.mri.2021.04.004
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10
PFKFB3-mediated Pro-glycolytic Shift in Hepatocellular Carcinoma Proliferation
Autor: Qianhui Dou, Aaron K. Grant, Cody Callahan, Patricia Coutinho de Souza, David Mwin, Adam L. Booth, Imad Nasser, Marwan Moussa, Muneeb Ahmed, Leo L. Tsai
Publikováno v: Cellular and molecular gastroenterology and hepatology. 15(1)
Metabolic reprogramming, in particular, glycolytic regulation, supports abnormal survival and growth of hepatocellular carcinoma (HCC) and could serve as a therapeutic target. In this study, we sought to identify glycolytic regulators in HCC that cou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1cc889005b2145a71a49a7861cf4ac
https://pubmed.ncbi.nlm.nih.gov/36162723
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