Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Patricia Collin-Osdoby"'
Autor:
Frederick A. Anderson, Ling Li, Patricia Collin-Osdoby, Merry Jo Oursler, David Webber, Philip Osdoby
Publikováno v:
Journal of Bone and Mineral Research. 6:375-385
Among the many different methods that have been used to obtain and study isolated osteoclasts from a variety of species, the egg-laying hen maintained on a low-calcium diet has proven to be one of the richest sources of relatively large numbers of os
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af752b8fb36d784f0f8a4aa6b33ab826
https://doi.org/10.1002/jbmr.5650060409
https://doi.org/10.1002/jbmr.5650060409
Publikováno v:
Journal of Bone and Mineral Research. 6:1353-1365
Osteoclasts are the major cell type responsible for normal and pathologic bone resorption. Obtaining highly purified populations of these multinucleated cells has been problematic, although such populations would greatly facilitate investigations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50885807a13905820e9b90c578c41cff
https://doi.org/10.1002/jbmr.5650061213
https://doi.org/10.1002/jbmr.5650061213
Publikováno v:
Journal of Biological Chemistry. 281:15809-15820
Nitric oxide (NO) is a multifunctional signaling molecule and a key vasculoprotective and potential osteoprotective factor. NO regulates normal bone remodeling and pathological bone loss in part through affecting the recruitment, formation, and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b1459383b261ae46d5467f8a254edf
https://doi.org/10.1074/jbc.m513225200
https://doi.org/10.1074/jbc.m513225200
Publikováno v:
Journal of Bone and Mineral Research. 21:183-192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab36978a517f2c0fd83e21a33f9550d8
https://doi.org/10.1359/jbmr.050917
https://doi.org/10.1359/jbmr.050917
Autor:
William F. Maloney, Libby Kindle, Lorinda M. Wright, Xuefeng Yu, Patricia Collin-Osdoby, Philip Osdoby
Publikováno v:
Bone. 36:840-853
Osteoclasts (Oc) derive from hematopoietic precursors present in the circulation and bone marrow, and they differentiate into multinucleated bone-resorbing cells in response to the dual essential signals receptor activator of NF-kappaB ligand (RANKL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d55cc280ab1ccf39f5f260e285e7051
https://doi.org/10.1016/j.bone.2005.01.021
https://doi.org/10.1016/j.bone.2005.01.021
Autor:
Patricia Collin-Osdoby
Publikováno v:
Circulation Research. 95:1046-1057
Vascular calcification often occurs with advancing age, atherosclerosis, various metabolic disorders such as diabetes mellitus and end-stage renal disease, or in rare genetic diseases, leading to serious clinical consequences. Such mineralization can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1586fce202ed196731dc9739d4cdde20
https://doi.org/10.1161/01.res.0000149165.99974.12
https://doi.org/10.1161/01.res.0000149165.99974.12
Publikováno v:
Journal of Bone and Mineral Research. 18:1404-1418
Signals targeting OCs to bone and resorption sites are not well characterized. A chemoattractant receptor (CXCR4), highly expressed in murine OC precursors, mediated their chemokine (SDF-1)-induced chemoattraction, collagen transmigration, and MMP-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb92a77a96d47f7514168343c8e57ab
https://doi.org/10.1359/jbmr.2003.18.8.1404
https://doi.org/10.1359/jbmr.2003.18.8.1404
Autor:
Frederick A. Anderson, Patricia Collin-Osdoby, Yuefang Huang, Philip Osdoby, Linda Rothe, Simon Bekker
Publikováno v:
Journal of Bone and Mineral Research. 17:1859-1871
Increased local osteoclast (OC)-mediated bone resorption coincides with angiogenesis in normal bone development and fracture repair, as well as in pathological disorders such as tumor-associated osteolysis and inflammatory-related rheumatoid arthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f03baf1f1e4194545d4cbb237b9167e
https://doi.org/10.1359/jbmr.2002.17.10.1859
https://doi.org/10.1359/jbmr.2002.17.10.1859
Publikováno v:
Journal of Clinical Investigation. 103:1409-1418
Declining estrogen levels during the first postmenopausal decade lead to rapid bone loss and increased fracture risk that can be reversed by estrogen replacement therapy. The bone-protective effects of estrogen may involve suppression of inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa3567406d445047d583edf42450d1b
https://doi.org/10.1172/jci4682
https://doi.org/10.1172/jci4682
Autor:
Alfie Tsay, Lala R. Chaudhary, Linda Rothe, Steven R. Goldring, Louis V. Avioli, Philip Osdoby, Patricia Collin-Osdoby, Teresa Sunyer, Yan Chen
Publikováno v:
Endocrinology. 139:4353-4363
Chemokines, including interleukin-8 (IL-8), function as key mediators in diverse inflammatory disorders via promoting the recruitment, proliferation, and activation of vascular and immune cells. IL-8 levels are elevated in inflammatory diseases, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea0a091656f51ff18bc17e1b0ceaee9
https://doi.org/10.1210/endo.139.10.6247
https://doi.org/10.1210/endo.139.10.6247