Thyrotoxicosis Involves β2-Adrenoceptor Signaling to Negatively Affect Microarchitecture and Biomechanical Properties of the Femur

Autor: Vanda Jorgetti, Nathalia Juliana Nardelli Gonçalves, Cecilia H. A. Gouveia, Rudá Prestes e Albuquerque, Manuela Miranda-Rodrigues, Bianca Neofiti-Papi, Julio C.B. Ferreira, Patricia Chacur Brum

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Background: Thyrotoxicosis increases bone turnover, resulting in net bone loss. Sympathetic nervous system (SNS) activation, via β2-adrenoceptor (β2-AR) signaling, also has osteopenic effects. Because thyroid hormones (TH) interact with the SNS to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf506e25dd95587527d1675c9cca2f7
https://doi.org/10.1089/thy.2018.0259