Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Patricia C. Schmid"'
Autor:
Harald S. Hansen, Steen Honoré Hansen, Gitte Petersen, Camilla Sørensen, Harald H.O. Schmid, Andreas Artmann, Philip J. Larsen, Patricia C. Schmid, Mads Tang-Christensen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1761:143-150
The anorectic lipid oleoylethanolamide and the orexigenic lipid anandamide both belong to the group of N-acylethanolamines that are generated by the enzyme N-acylphosphatidylethanolamine-hydrolyzing phospholipase D. The levels of the two bioactive li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c472d9b97bbfa96e2450ab7bb16240
https://doi.org/10.1016/j.bbalip.2005.12.011
https://doi.org/10.1016/j.bbalip.2005.12.011
Autor:
Randy J. Krebsbach, Jun Wang, Natsuo Ueda, Harald H.O. Schmid, Yasuo Okamoto, Jun Morishita, Patricia C. Schmid
Publikováno v:
Biochemical Journal. 389:241-247
In animal tissues, NAEs (N-acylethanolamines), including N-arachidonoylethanolamine (anandamide), are primarily formed from their corresponding NAPEs (N-acylphosphatidylethanolamines) by a phosphodiesterase of the PLD (phospholipase D) type (NAPE-PLD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa009e30fdf32a1ff1812b66300014b5
https://doi.org/10.1042/bj20041790
https://doi.org/10.1042/bj20041790
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1734:215-219
N-Acylethanolamines (NAEs) and N-acylphosphatidylethanolamines (NAPEs) are trace constituents of vertebrate cells and tissues and much is known about their metabolism and possible function in animals. Here we report for the first time the identificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f28becb02f4234f5845b6dd64d7ceb
https://doi.org/10.1016/j.bbalip.2005.03.004
https://doi.org/10.1016/j.bbalip.2005.03.004
Autor:
Patricia C. Schmid, Michael Kosteljanetz, Harald H.O. Schmid, Harald S. Hansen, Helle Broholm, Birthe Moesgaard, Gitte Petersen
Publikováno v:
Journal of Neurochemistry. 93:299-309
The endogenous levels of the two cannabinoid receptor ligands 2-arachidonoyl glycerol and anandamide, and their respective congeners, monoacyl glycerols and N-acylethanolamines, as well as the phospholipid precursors of N-acylethanolamines, were meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::506c7191d7bdcca2de0aed578d9cd503
https://doi.org/10.1111/j.1471-4159.2005.03013.x
https://doi.org/10.1111/j.1471-4159.2005.03013.x
Autor:
Patricia C. Schmid, W.R. Schäbitz, Stefan Schwab, Christian Berger, Margit Wolf, Harald H.O. Schmid
Publikováno v:
Journal of Neurochemistry. 88:1159-1167
We investigated levels and compositions of N-acylethanolamines (NAEs) and their precursors, N-acyl phosphatidylethanolamines (N-acyl PEs), in a rat stroke model applying striatal microdialysis for glutamate assay. Rats (n = 18) were treated with eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c922fd9800a8661820586f4da9218ca
https://doi.org/10.1046/j.1471-4159.2003.02244.x
https://doi.org/10.1046/j.1471-4159.2003.02244.x
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 304:713-722
Intraluminal administration of the endocannabinoids N-arachidonoyl-ethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG) causes inflammation similar to that caused by Clostridium difficile toxin A in the rat ileum. The effects of anandamide and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b25624285e0a37688ba2fb961ee2117
https://doi.org/10.1124/jpet.102.043893
https://doi.org/10.1124/jpet.102.043893
Autor:
Harald H.O. Schmid, Evgueni V. Berdyshev, Patricia C. Schmid, Randy J. Krebsbach, Lester E. Wold
Publikováno v:
Lipids. 37:907-912
Long-chain N-acylethanolamines (NAE), including the endocannabinoid, anandamide, accumulate in mammalian tissues under a variety of pathological conditions. They have also been shown to inhibit the growth of various cancer cell lines in vitro. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c156295f74883b60ae4890b93472c0d
https://doi.org/10.1007/s11745-002-0978-z
https://doi.org/10.1007/s11745-002-0978-z
Autor:
Isabel Lastres-Becker, Javier Fernández-Ruiz, Jorge Manzanares, Petra Bittigau, Harald H.O. Schmid, Chrysanthy Ikonomidou, Henrik H. Hansen, Harald S. Hansen, Fernando Berrendero, Patricia C. Schmid
Publikováno v:
Journal of Neurochemistry. 78:1415-1427
Endogenous cannabinoid receptor ligands (endocannabinoids) may rescue neurons from glutamate excitotoxicity. As these substances also accumulate in cultured immature neurons following neuronal damage, elevated endocannabinoid concentrations may be in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8dab209fd20582d8c3e359adc91ba23
https://doi.org/10.1046/j.1471-4159.2001.00542.x
https://doi.org/10.1046/j.1471-4159.2001.00542.x
Autor:
Evgueni V. BERDYSHEV, Patricia C. SCHMID, Randy J. KREBSBACH, Cecilia J. HILLARD, Chuanshu HUANG, Nanyue CHEN, Zigang DONG, Harald H.O. SCHMID
Publikováno v:
Biochemical Journal. 360:67-75
Anandamide and other polyunsaturated N-acylethanolamines (NAEs) exert biological activity by binding to cannabinoid receptors. These receptors are linked to Gi/o proteins and their activation leads to extracellular-signal-regulated protein kinase (ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4586f89135aa24f548ae81798e09c412
https://doi.org/10.1042/bj3600067
https://doi.org/10.1042/bj3600067
Autor:
Peter Mattjus, Yiguo Zhang, Harald H.O. Schmid, Wei-Ya Ma, Zigang Dong, Shuping Zhong, Ann M. Bode, Rhoderick E. Brown, Ziming Dong, Patricia C. Schmid
Publikováno v:
Journal of Biological Chemistry. 276:11775-11782
The sphingomyelin-ceramide pathway is an evolutionarily conserved ubiquitous signal transduction system that regulates many cell functions including apoptosis. Sphingomyelin (SM) is hydrolyzed to ceramide by different sphingomyelinases. Ceramide serv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867e1fac9d0f54c2621e037f7f1eb926
https://doi.org/10.1074/jbc.m006000200
https://doi.org/10.1074/jbc.m006000200