Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Patricia C. Pillow"'
Autor:
Xifeng Wu, Matthew B. Schabath, Patricia C. Pillow, George L. Delclos, Margaret R. Spitz, Ladia M. Hernandez, Seth P. Lerner, H. Barton Grossman
Publikováno v:
Nutrition and Cancer. 53:144-151
Dietary folate, a water-soluble B vitamin found in a variety of fruits and vegetables, is of particular interest as a chemopreventive agent due to its role in DNA methylation and DNA synthesis and repair. We hypothesized that individuals with low fol
Autor:
Zhengdong Zhang, Guojun Li, Qingyi Wei, Patricia C. Pillow, Qiuling Shi, Margaret R. Spitz, Ladia M. Hernandez
Publikováno v:
Pharmacogenetics and Genomics. 15:547-555
Although tobacco is the major lung cancer risk factor, folate deficiency has also been implicated as a risk. Methionine synthase (MS; gene symbol, MTR) and methionine synthase reductase (MSR; gene symbol, MTRR) play important roles in the folate meta
Autor:
Matthew B. Schabath, Ladia M. Hernandez, Ivan P. Gorlov, Margaret R. Spitz, Yunfei Wang, Jie Lin, Xifeng Wu, Patricia C. Pillow, H. Barton Grossman
Publikováno v:
Carcinogenesis. 25:1639-1647
Epidemiological studies have shown an association between low folate intake and an increased cancer risk. Major genes involved in folate metabolism include methylene-tetrahydrofolate reductase (MTHFR) and methionine synthase (MS). We investigated joi
Autor:
Jelena Jakovljevic, Patricia C. Pillow, S. Eva Singletary, Marina S. Touillaud, Shine Chang, Melissa L. Bondy
Publikováno v:
Breast Cancer Research and Treatment. 75:5-14
Although a wealth of research has focused on the influence of diet on breast cancer risk, the relationships between dietary factors and tumor characteristics of breast cancer, like estrogen receptor (ER) status, are not well characterized. In a case-
Autor:
Y. Yaohua Hu, Patricia C. Pillow, Waun Ki Hong, Margaret R. Spitz, Christopher I. Amos, Michelle A. Detry, Xifeng Wu
Publikováno v:
Nutrition Research. 20:371-380
The mesocorticolimbic dopaminergic reward pathways have a role in the neuromodulation of appetite. There are data supporting a role of allelic variants of the D2 dopamine receptor ( DRD 2) gene and the number of receptor binding sites in vulnerabilit
Autor:
Anne M. Sweeney, Cherie M. Duphorne, Sara S. Strom, Patricia C. Pillow, Robert J. Amato, Lawrence P. Hutchinson, Alice J. Sigurdson, J. Fred Annegers, Shine Chang
Publikováno v:
Nutrition and Cancer. 34:20-26
No risk factor other than cryptorchidism has been consistently associated with testicular cancer, and the influence of diet on testicular cancer risk has not been extensively explored. A few studies have found increased testicular cancer risk in men
Autor:
Yuko Yamamura, Patricia C. Pillow, Richard J. Babaian, Margaret R. Spitz, Cherie M. Duphorne, Stephen D. Hursting, Sara S. Strom
Publikováno v:
Nutrition and Cancer. 33:20-25
In the last several years, attention has been focused on comparing the Western diet, which is rich in fat, protein, and refined carbohydrates, with the Asian diet, which is rich in phytoestrogens, as a possible explanation for the contrasting rates o
Publikováno v:
JAMA. 294(12)
ContextDespite lung-specific in vitro and in vivo studies that support a chemopreventive role for phytoestrogens, there has been little epidemiologic research focused on dietary intake of phytoestrogens and risk of lung cancer.ObjectiveTo examine the
Autor:
Qingyi Wei, Guojun Li, Qiuling Shi, Patricia C. Pillow, Margaret R. Spitz, Zhendong Zhang, Ladia M. Hernandez
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 14(6)
Methylenetetrahydrofolate reductase (MTHFR) catalyzes the metabolism of folate and nucleotides needed for DNA synthesis and repair. Variations in MTHFR functions likely play roles in the etiology of lung cancer. The MTHFR gene has three nonsynonymous
Autor:
Shine Chang, Patricia C. Pillow, Donghui Li, Marina S. Touillaud, S. Eva Singletary, Melissa L. Bondy, Jelena Jakovljevic
Publikováno v:
Nutrition and cancer. 51(2)
Although many dietary studies have focused on breast cancer risk, few have examined dietary influence on tumor characteristics such as estrogen receptor (ER) status. Because phytoestrogens may modulate hormone levels and ER expression, we analyzed ER