Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Patricia C. Ewing"'
Autor:
Morteza Salarzaei, Ralf L. O. van de Laar, Patricia C. Ewing-Graham, Shiva Najjary, Edith van Esch, Heleen J. van Beekhuizen, Dana A. M. Mustafa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6205 (2024)
This study aims to refine our understanding of the inherent heterogeneity in cervical cancer by exploring differential gene expression profiles, immune cell infiltration dynamics, and implicated signaling pathways in the two predominant histological
Externí odkaz:
https://doaj.org/article/bc73d63dcd45487d8cf93c81893fbdb6
Autor:
Gatske M. Nieuwenhuyzen-de Boer, Nick J. van de Berg, Xu Shan Gao, Patricia C. Ewing-Graham, Heleen J. van Beekhuizen
Publikováno v:
Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Background The aim of surgery for advanced-stage ovarian cancer is a complete cytoreduction, because this is the most important independent prognostic factor for prolonged survival. Yet this can be difficult to achieve when there are microme
Externí odkaz:
https://doaj.org/article/dac929f76a634314be8489aef5522e2b
Identifying Molecular Changes in Early Cervical Cancer Samples of Patients That Developed Metastasis
Autor:
Vera de Geus, Patricia C. Ewing-Graham, Willem de Koning, Maurits N. C. de Koning, Thierry P. P. van den Bosch, Alex L. Nigg, Casper H. J. van Eijck, Marta Jozwiak, Heleen J. van Beekhuizen, Dana A. M. Mustafa
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Cervical cancer is one of the most common cancers in women worldwide. Patients diagnosed with early-stage cervical cancer have a good prognosis, however, 10-20% suffer from local or distant recurrent disease after primary treatment. Treatment options
Externí odkaz:
https://doaj.org/article/83c09f01613e4e1dbc7b273099940269
Autor:
Sharline M. van Vliet-Pérez, Nick J. van de Berg, Francesca Manni, Marco Lai, Lucia Rijstenberg, Benno H. W. Hendriks, Jenny Dankelman, Patricia C. Ewing-Graham, Gatske M. Nieuwenhuyzen-de Boer, Heleen J. van Beekhuizen
Publikováno v:
Cancers, Vol 14, Iss 6, p 1422 (2022)
The most important prognostic factor for the survival of advanced-stage epithelial ovarian cancer (EOC) is the completeness of cytoreductive surgery (CRS). Therefore, an intraoperative technique to detect microscopic tumors would be of great value. T
Externí odkaz:
https://doaj.org/article/8b6224deb4c948e39a640177a02acbab
Autor:
Shatavisha Dasgupta, Patricia C. Ewing-Graham, Sigrid M. A. Swagemakers, Thierry P. P. van den Bosch, Peggy N. Atmodimedjo, Michael M. P. J. Verbiest, Marit de Haan, Helena C. van Doorn, Peter J. van der Spek, Senada Koljenović, Folkert J. van Kemenade
Publikováno v:
Cancers, Vol 13, Iss 14, p 3580 (2021)
DNA methylation is the most widely studied mechanism of epigenetic modification, which can influence gene expression without alterations in DNA sequences. Aberrations in DNA methylation are known to play a role in carcinogenesis, and methylation prof
Externí odkaz:
https://doaj.org/article/a688be0a377145fba6a95d6e5b83e043
Autor:
Shatavisha Dasgupta, Senada Koljenović, Thierry P. P. van den Bosch, Sigrid M. A. Swagemakers, Nick M. A. van der Hoeven, Ronald van Marion, Peter J. van der Spek, Helena C. van Doorn, Folkert J. van Kemenade, Patricia C. Ewing-Graham
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 324 (2021)
Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC), can be challenging, as features of dVIN may mimic those of non-dysplastic
Externí odkaz:
https://doaj.org/article/4ab532fc214745e183edcf0623f169a2
Autor:
Silvia R. Vitale, Floris H. Groenendijk, Ronald van Marion, Corine M. Beaufort, Jean C. Helmijr, Hendrikus Jan Dubbink, Winand N. M. Dinjens, Patricia C. Ewing-Graham, Ramon Smolders, Helena C. van Doorn, Ingrid A. Boere, Els M. J. J. Berns, Jozien Helleman, Maurice P. H. M. Jansen
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 415 (2020)
The aim of this study was to determine an optimal workflow to detect TP53 mutations in baseline and longitudinal serum cell free DNA (cfDNA) from high-grade serous ovarian carcinomas (HGSOC) patients and to define whether TP53 mutations are suitable
Externí odkaz:
https://doaj.org/article/76c9e3e5ee1348d4b952b7c5f009f099
Publikováno v:
Rare Tumors, Vol 2, Iss 3, Pp e39-e39 (2010)
Monodermal teratomas of the ovary can take the form of carcinoid tumors of which there are several types, mucinous carcinoid being the least common. Very few cases of primary mucinous carcinoid of the ovary have been reported in the literature and th
Externí odkaz:
https://doaj.org/article/4f83904dad0e4bca8a47c6cb9e088055
Autor:
Erica W.M. Janszen, Helena C. Van Doorn, Patricia C. Ewing, Ronald R. De Krijger, Johannes H.W. De Wilt, Boen L.R. Kam, Wouter W. De Herder
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2 (2008)
Background Malignant struma ovarii is a rare malignant germ cell tumor of the ovary. Due to the rarity of this disease, treatment has not been uniform throughout the published literature. Cases We present three cases of malignant struma ovarii. Follo
Externí odkaz:
https://doaj.org/article/39ed1381a8f04f3287a9269f16ae53fe
Autor:
Jasmijn Vaneman, Heleen J. van Beekhuizen, Joost L. Boormans, Patricia C. Ewing-Graham, Geert J. L. H. van Leenders, Ramon G. V. Smolders, H C. van Doorn
Publikováno v:
Virchows Archiv. Springer-Verlag
Diagnosis of lymph node metastases in pelvic lymph node dissection (PLND) is important for staging and treatment. Standard practice is to submit visible or palpable lymph nodes for histology. We assessed the added value of embedding all residual fatt