Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Patricia C. Cogswell"'
Autor:
Albert S. Baldwin, Denise E. Dunn, William A. Weiss, Anders Persson, Barbara Calamini, Patricia C. Cogswell, Donald C. Lo, Amanda L. Rinkenbaugh
Publikováno v:
Oncotarget
Oncotarget, vol 7, iss 43
Oncotarget, vol 7, iss 43
// Amanda L. Rinkenbaugh 1,2 , Patricia C. Cogswell 2,3 , Barbara Calamini 4 , Denise E. Dunn 4 , Anders I. Persson 5,6 , William A. Weiss 5,6 , Donald C. Lo 4 and Albert S. Baldwin 2 1 Department of Pathology and Laboratory Medicine, University of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5083d623b5bc5c30b5b7e2b00662a0
https://doi.org/10.18632/oncotarget.12507
https://doi.org/10.18632/oncotarget.12507
Publikováno v:
Genes & Cancer
Activating mutations in KRAS are prevalent in cancer, but therapies targeted to oncogenic RAS have been ineffective to date. These results argue that targeting downstream effectors of RAS will be an alternative route for blocking RAS-driven oncogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19eb05717753dab0ea85ee0e95c35153
http://europepmc.org/articles/PMC4063255
http://europepmc.org/articles/PMC4063255
Publikováno v:
Oncogene. 30:1727-1732
The induction of mammalian autophagy, a cellular catabolic bulk-degradation process conserved from humans to yeast, was recently shown to require IκB kinase (IKK), the upstream regulator of the nuclear factor (NF)-κB pathway. Interestingly, it was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984165591935b7dd6f39065ce355ff6e
https://doi.org/10.1038/onc.2010.553
https://doi.org/10.1038/onc.2010.553
Publikováno v:
Oncogene
The membrane bound receptor tyrosine kinase Her2 is overexpressed in approximately 30% of human breast cancers, which correlates with poor prognosis. Her2-induced signaling pathways include MAPK and PI3K/Akt, of which the latter has been shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c820f70f9215d02cc65e7cb676f14ccb
https://doi.org/10.1038/onc.2009.410
https://doi.org/10.1038/onc.2009.410
Autor:
Albert S. Baldwin, Jenny P.-Y. Ting, Patricia C. Cogswell, Joseph A. Duncan, Han C. Dan, Matthew J. Cooper
Publikováno v:
Genes & Development. 22:1490-1500
While NF-κB is considered to play key roles in the development and progression of many cancers, the mechanisms whereby this transcription factor is activated in cancer are poorly understood. A key oncoprotein in a variety of cancers is the serine–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c28adc8c3e3b5d9d840f32d76d6b84b
https://doi.org/10.1101/gad.1662308
https://doi.org/10.1101/gad.1662308
Publikováno v:
Journal of Biological Chemistry. 281:12521-12525
Phosphorylation of histone H3 protein at serine 10 is an important step in chromatin remodeling during transcriptional transactivation. IkappaB kinase-alpha (IKK-alpha) and Mitogen- and Stress-activated protein Kinases 1 and 2 (MSK1/2) have been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfd86312d4aaf65397239fee679ff71
https://doi.org/10.1074/jbc.m513333200
https://doi.org/10.1074/jbc.m513333200
Publikováno v:
Genes & Development. 20:225-235
While Bcl-3 expression in cancer was originally thought to be limited to B-cell lymphomas with a 14;19 chromosomal translocation, more recent evidence indicates that expression of this presumptive oncoprotein is significantly more widespread in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413298758b3cb5741c955619a5f54d06
https://doi.org/10.1101/gad.1352206
https://doi.org/10.1101/gad.1352206
Autor:
Albert S. Baldwin, Richard A. Flavell, Juan-Jose Ventura, Patricia C. Cogswell, Roger J. Davis
Publikováno v:
Genes & Development. 18:2905-2915
The c-Jun NH2-terminal kinase (JNK) has been implicated in both cell death and survival responses to different stimuli. Here we reexamine the function of JNK in tumor necrosis factor (TNF)-stimulated cell death using fibroblasts isolated from wild-ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc61bc3a1dcdad2e87c5c53ff03a0dd
https://doi.org/10.1101/gad.1223004
https://doi.org/10.1101/gad.1223004
Publikováno v:
Journal of Biological Chemistry. 279:31183-31189
Mitogenic activation of expression of immediate-early genes, such as c-fos, is controlled through signal-induced phosphorylation of constitutively bound transcription factors that is correlated with a nucleosomal response that involves inducible chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3408e6180551e6b578dbf7338274f821
https://doi.org/10.1074/jbc.m404380200
https://doi.org/10.1074/jbc.m404380200
Autor:
Cindy L. Bristow, Albert S. Baldwin, Denis C. Guttridge, Jayne A. Keifer, Sophie Roy, Julie Y. Reuther, Patricia C. Cogswell, Donald W. Nicholson, David F. Kashatus
Publikováno v:
Journal of Biological Chemistry. 278:2963-2968
The transcription factor NF-kappa B has been shown to be predominantly cytoplasmically localized in the absence of an inductive signal. Stimulation of cells with inflammatory cytokines such as tumor necrosis factor alpha or interleukin-1 induces the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee6695a9fe854f1d4319fd4bfb66766
https://doi.org/10.1074/jbc.m209995200
https://doi.org/10.1074/jbc.m209995200