Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Patricia C. Brum"'
Autor:
Gabriel C. Tobias, João L. P. Gomes, Larissa G. Fernandes, Vanessa A. Voltarelli, Ney R. de Almeida, Paulo R. Jannig, Rodrigo W. Alves de Souza, Carlos E. Negrão, Edilamar M. Oliveira, Roger Chammas, Christiano R. R. Alves, Patricia C. Brum
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Exercise training reduces the incidence of several cancers, but the mechanisms underlying these effects are not fully understood. Exercise training can affect the spleen function, which controls the hematopoiesis and immune response. Analyzi
Externí odkaz:
https://doaj.org/article/bb7703a675b442b8b22b05fcb7e4556e
Autor:
Felipe C. Vechin, Jakob L. Vingren, Guilherme D. Telles, Miguel S. Conceicao, Cleiton A. Libardi, Manoel E. Lixandrao, Felipe Damas, Telma F. Cunha, Patricia C. Brum, Luiz A. Riani, Carlos Ugrinowitsch
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionResistance exercise can significantly increase serum steroid concentrations after an exercise bout. Steroid hormones are involved in the regulation of several important bodily functions (e.g., muscle growth) through both systemic delivery
Externí odkaz:
https://doaj.org/article/52f0a1b2a1e14af9a9637baad92bf297
Autor:
Natan D. da Silva, Aluisio Andrade-Lima, Marcel R. Chehuen, Anthony S. Leicht, Patricia C. Brum, Edilamar M. Oliveira, Nelson Wolosker, Bruno R. A. Pelozin, Tiago Fernandes, Cláudia L. M. Forjaz
Publikováno v:
Genes, Vol 14, Iss 1, p 101 (2022)
Patients with peripheral artery disease (PAD) have reduced muscle capillary density. Walking training (WT) is recommended for PAD patients. The goal of the study was to verify whether WT promotes angiogenesis in PAD-affected muscle and to investigate
Externí odkaz:
https://doaj.org/article/91a4e7fc67f244799038a95244ca92aa
Autor:
Ligia M. Antunes‐Correa, Patricia F. Trevizan, Aline V.N. Bacurau, Larissa Ferreira‐Santos, João L.P. Gomes, Ursula Urias, Patricia A. Oliveira, Maria Janieire N.N. Alves, Dirceu R. deAlmeida, Patricia C. Brum, Edilamar M. Oliveira, Ludhmila Hajjar, Roberto Kalil Filho, Carlos Eduardo Negrão
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 1, Pp 89-102 (2020)
Abstract Background The exercise intolerance in chronic heart failure with reduced ejection fraction (HFrEF) is mostly attributed to alterations in skeletal muscle. However, the mechanisms underlying the skeletal myopathy in patients with HFrEF are n
Externí odkaz:
https://doaj.org/article/68a9d1c662894318928186b7ce730491
Autor:
Igor L. Gomes-Santos, Camila P. Jordão, Clevia S. Passos, Patricia C. Brum, Edilamar M. Oliveira, Roger Chammas, Anamaria A. Camargo, Carlos E. Negrão
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Doxorubicin causes cardiotoxicity and exercise intolerance. Pre-conditioning exercise training seems to prevent doxorubicin-induced cardiac damage. However, the effectiveness of the cardioprotective effects of exercise training concomitantly with dox
Externí odkaz:
https://doaj.org/article/95c474447a1644acbef0b5a2579f4830
Autor:
Rodrigo W. Alves de Souza, David Gallo, Ghee Rye Lee, Eri Katsuyama, Alexa Schaufler, Janick Weber, Eva Csizmadia, George C. Tsokos, Lauren G. Koch, Steven L. Britton, Ulrik Wisløff, Patricia C. Brum, Leo E. Otterbein
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109018- (2021)
Summary: Physical exercise has profound effects on quality of life and susceptibility to chronic disease; however, the regulation of skeletal muscle function at the molecular level after exercise remains unclear. We tested the hypothesis that the ben
Externí odkaz:
https://doaj.org/article/6b7b353c78914a5ea96007141e2a3be5
Autor:
Tassia S. R. da Costa, Ursula Urias, Marcelo V. Negrao, Camila P. Jordão, Clévia S. Passos, Igor L. Gomes‐Santos, Vera Maria C. Salemi, Anamaria A. Camargo, Patricia C. Brum, Edilamar M. Oliveira, Ludhmila A. Hajjar, Roger Chammas, Roberto K. Filho, Carlos E. Negrao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Patients treated for breast cancer have a high incidence of cardiovascular complications. In this study, we evaluated the impact of breast cancer on cardiac function and cardiomyocyte Ca2+‐handling protein expression. We also investigate
Externí odkaz:
https://doaj.org/article/be2bbc7f046e46d99d39ba8c807b345d
Autor:
Ainhoa Arana Echarri, Mark Beresford, John P. Campbell, Robert H. Jones, Rachel Butler, Kenneth J. Gollob, Patricia C. Brum, Dylan Thompson, James E. Turner
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Breast cancer is the most common malignancy among women worldwide. Over the last four decades, diagnostic and therapeutic procedures have improved substantially, giving patients with localized disease a better chance of cure, and those with more adva
Externí odkaz:
https://doaj.org/article/f807173b5d584635ba80aabeca1f7f63
Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN
Autor:
Christiano R.R. Alves, Willian das Neves, Ney R. de Almeida, Eric J. Eichelberger, Paulo R. Jannig, Vanessa A. Voltarelli, Gabriel C. Tobias, Luiz R.G. Bechara, Daniele de Paula Faria, Maria J.N. Alves, Lars Hagen, Animesh Sharma, Geir Slupphaug, José B.N. Moreira, Ulrik Wisloff, Michael F. Hirshman, Carlos E. Negrão, Gilberto de Castro Jr, Roger Chammas, Kathryn J. Swoboda, Jorge L. Ruas, Laurie J. Goodyear, Patricia C. Brum
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp 101012- (2020)
Objective: We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. Methods: We used multiple in vivo and in vitro methods to explore the mechanisms underlying the beneficial effects i
Externí odkaz:
https://doaj.org/article/be8202df0b80459fac41942eb9eb9047
Autor:
Marcelo G. Pereira, Vanessa A. Voltarelli, Gabriel C. Tobias, Lara de Souza, Gabriela S. Borges, Ailma O. Paixão, Ney R. de Almeida, Thomas Scott Bowen, Marilene Demasi, Elen H. Miyabara, Patricia C. Brum
Publikováno v:
Cancers, Vol 14, Iss 1, p 28 (2021)
Cancer cachexia is a multifactorial and devastating syndrome characterized by severe skeletal muscle mass loss and dysfunction. As cachexia still has neither a cure nor an effective treatment, better understanding of skeletal muscle plasticity in the
Externí odkaz:
https://doaj.org/article/86b84c6b89af4701a756e145a1c89d72