Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Patricia Bolanos-Palmieri"'
Autor:
Temitayo O Idowu, Valerie Etzrodt, Benjamin Seeliger, Patricia Bolanos-Palmieri, Kristina Thamm, Hermann Haller, Sascha David
Publikováno v:
eLife, Vol 9 (2020)
Endothelial Tie2 signaling plays a pivotal role in vascular barrier maintenance at baseline and after injury. We previously demonstrated that a sharp drop in Tie2 expression observed across various murine models of critical illnesses is associated wi
Externí odkaz:
https://doaj.org/article/3c273d0291344f799a565c38b0b7ae32
Autor:
Mario Schiffer, Jan Hinrich Bräsen, Heiko Schenk, R. White, H. Haller, Janina Müller-Deile, Patricia Bolanos-Palmieri, Lynne Beverly-Staggs, Patricia Schroder
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Hermansky-Pudlak Syndrome (HPS) is a rare disease caused by mutations in the genes coding for various HPS proteins. HPS proteins are part of multi-subunit complexes involved in the biogenesis of organelles from the lysosomal-endosomal-system. In huma
Autor:
Patricia Bolanos-Palmieri, Mario Schiffer, Patricia Schroder, Heiko Schenk, Heike Bähre, Ahmed Kotb
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Tryptophan catabolism is carried out by the enzymes of the kynurenine pathway leading to the de novo synthesis of NAD and the production of a series of bioactive metabolites. Kynurenine 3-Monooxigenase (KMO) is a key component of
Autor:
Janina Müller-Deile, Tilman Jobst-Schwan, Mario Schiffer, Ruth I. Johnson, Hermann Haller, Thomas F. Reubold, Irini Tossidou, Laura de Jonge, Susanne Eschenburg, Patricia Bolanos-Palmieri, Beina Teng, Dana M Drost, Christian Kardinal, Kirstin Worthmann, Jonas M. Willerding, Patricia Schroder
Publikováno v:
J Am Soc Nephrol
BACKGROUND: CD2-associated protein (CD2AP), a slit diaphragm–associated scaffolding protein involved in survival and regulation of the cytoskeleton in podocytes, is considered a “stabilizer” of the slit diaphragm complex that connects the slit
Autor:
Mario Schiffer, Alysha Higgs, Janina Müller-Deile, Philipp Niggemann, Patricia Schroder, Beina Teng, Patricia Bolanos-Palmieri, Hermann Haller, Heiko Schenk, Lynne Staggs
Publikováno v:
Biology Open
Biology Open, Vol 8, Iss 3 (2019)
Biology Open, Vol 8, Iss 3 (2019)
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Up to now, no drugs that specifically target the actin cytoskeleton of po
Autor:
Michaela Beese, Hermann Haller, Patricia Schroder, Anna Masseli, Heiko Schenk, Patricia Bolanos-Palmieri, Jan Hinrich Bräsen, Jan Hegermann
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2019 (2019)
BioMed Research International, Vol 2019 (2019)
The 6-O-endosulfatases (sulfs) are important enzymatic components involved in the regulation of heparan sulfate by altering the sulfatation pattern. Specifically in the kidney, sulfs have been implicated in the glomerular podocyte-endothelial cell cr
Autor:
Patricia Schroder, K. Schulze, Florian Siegerist, Heiko Schenk, Janina Müller-Deile, Patricia Bolanos-Palmieri, Mario Schiffer, Nicole Endlich, H. Haller
Publikováno v:
Kidney international. 96(2)
Proteinuria can be induced by impairment of any component of the glomerular filtration barrier (GFB). To determine the role of circulating permeability factors on glomerular damage, we developed a parabiosis-based zebrafish model to generate a common
Autor:
Hermann Haller, Ron Korstanje, Patricia Schroder, Holly S. Savage, Mario Schiffer, Patricia Bolanos-Palmieri, Konstantin Deutsch, Ian Roberts, Nils Hanke, Jan Hinrich Bräsen, Susan Sheehan, Lynne Staggs
Publikováno v:
Journal of the American Society of Nephrology : JASN. 27(11)
Changes in metabolite levels of the kynurenine pathway have been observed in patients with CKD, suggesting involvement of this pathway in disease pathogenesis. Our recent genetic analysis in the mouse identified the kynurenine 3-mono-oxygenase (KMO)
Autor:
Konstantin Deutsch, Hermann Haller, Patricia Bolanos-Palmieri, Patricia Schroder, Mario Schiffer, Lynne Staggs
Publikováno v:
Nephrology Dialysis Transplantation. 31:i107-i107