Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Patricia Blanco-Gabella"'
Autor:
Andrea Canal-Martín, Javier Sastre, María José Sánchez-Barrena, Angeles Canales, Sara Baldominos, Naiara Pascual, Loreto Martínez-González, Dolores Molero, Mª Encarnación Fernández-Valle, Elena Sáez, Patricia Blanco-Gabella, Elena Gómez-Rubio, Sonsoles Martín-Santamaría, Almudena Sáiz, Alicia Mansilla, F. Javier Cañada, Jesús Jiménez-Barbero, Ana Martínez, Ruth Pérez-Fernández
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Dynamic combinatorial chemistry (DCC) is instrumental in the discovery of ligands for pharmaceutical targets. Here, the authors adapted DCC to work at 4 degrees Celsius and used it to identify a ligand for Neuronal Calcium Sensor-1 that promotes NCS-
Externí odkaz:
https://doaj.org/article/851d08b0cab545c2b42eefe2157d74fa
Autor:
Eva M García-Cuesta, Pablo Martínez, Karthik Selvaraju, Gabriel Ulltjärn, Adrián Miguel Gómez Pozo, Gianluca D'Agostino, Sofia Gardeta, Adriana Quijada-Freire, Patricia Blanco Gabella, Carlos Roca, Daniel del Hoyo, Rodrigo Jiménez-Saiz, Alfonso García-Rubia, Blanca Soler Palacios, Pilar Lucas, Rosa Ayala-Bueno, Noelia Santander Acerete, Yolanda Carrasco, Carlos Oscar Sorzano, Ana Martinez, Nuria E Campillo, Lasse D Jensen, Jose Miguel Rodriguez Frade, César Santiago, Mario Mellado
Publikováno v:
eLife, Vol 13 (2024)
CXCR4 is a ubiquitously expressed chemokine receptor that regulates leukocyte trafficking and arrest in both homeostatic and pathological states. It also participates in organogenesis, HIV-1 infection, and tumor development. Despite the potential the
Externí odkaz:
https://doaj.org/article/f6355c90de494368a3bd46842c4d4614
Autor:
Jesús Jiménez-Barbero, María José Sánchez-Barrena, F. Javier Cañada, Elena Gómez-Rubio, Almudena Sáiz, Patricia Blanco-Gabella, Elena Sáez, Sara Baldominos, Naiara Pascual, Alicia Mansilla, Javier Sastre, Ángeles Canales, Dolores Molero, Sonsoles Martín-Santamaría, Loreto Martínez-González, Ana Martínez, Ruth Pérez-Fernández, Mª Encarnación Fernández-Valle, Andrea Canal-Martín
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
13 p.-9 fig.-1 tab.
Dynamic combinatorial chemistry (DCC) has proven its potential in drug discovery speedingthe identification of modulators of biological targets. However, the exchange chemistriestypically take place under specific reaction co
Dynamic combinatorial chemistry (DCC) has proven its potential in drug discovery speedingthe identification of modulators of biological targets. However, the exchange chemistriestypically take place under specific reaction co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7679ce5725584876f93eee9255e5b0
http://link.springer.com/article/10.1038/s41467-019-10627-w
http://link.springer.com/article/10.1038/s41467-019-10627-w