Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Patricia Bentley"'
Autor:
Patricia Bentley
Publikováno v:
Journal of Mathematics and the Arts. 12:170-180
The astronomical instrument known as the astrolabe has been called star taker, mirror of the sun, and recently, the first personal computer. First developed by the ancient Greeks, it was refined and improved by scientists working in medieval Islamic
Autor:
Marie Blais, Douglas Ferguson, Mark Pietras, Jim Fikes, Abhishek G. Sathe, Sally A. Price, Anshul Gupta, Melanie Galvin, Michael R. Hale, Robert L. Walsky, Yvonne P. Dragan, Frank McGrath, Crystal Brown, Paul J. Ciaccio, Gunther Kern, Matthew Wagoner, Letitia Cheatham, Nakpangi Johnson, Patricia Bentley, Natalie Keirstead, Debra Snow, Wenli Luo, Jennifer C. Sasaki
Publikováno v:
Toxicological Sciences. 137:278-291
Despite six decades of clinical experience with the polymyxin class of antibiotics, their dose-limiting nephrotoxicity remains difficult to predict due to a paucity of sensitive biomarkers. Here, we evaluate the performance of standard of care and ne
Autor:
James Fikes, Mary Ann Gorko, Joanne Saye, Andy Zuvich, Patricia Bentley, David Brott, Melody Diamond, Pam Campbell, Letitia Cheatham
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:190-196
Introduction Drug-induced glucose dysregulation and insulin resistance have been associated with weight gain and potential induction and/or exacerbation of diabetes mellitus in the clinic suggesting they may be safety biomarkers when developing antip
Autor:
Letitia Cheatham, Murali V P Nadella, David Brott, Jim Fikes, Lewis B. Kinter, Wenli Luo, Dale Thurman, Patricia Bentley, Frank McGrath
Publikováno v:
Toxicology. 303:133-138
Alpha 2u-globulin mediated hyaline droplet nephropathy (HDN) is a male rat specific lesion induced when a compound or metabolite binds to alpha 2u-globulin. The objective of this study was to investigate if the newer and more sensitive renal biomarke
Autor:
Russell Bialecki, Wenli Luo, Yvonne P. Dragan, Harriet Kamendi, Herbert Barthlow, Nilaben Patel, Patricia Bentley, Natalie Keirstead, Debra Snow, Ying Zhou, Meredith Crosby
Publikováno v:
Toxicology and applied pharmacology. 289(3)
Doxorubicin (DOX) is a potent and effective broad-spectrum anthracycline antitumor agent, but its clinical usefulness is restricted by cardiotoxicity. This study compared pharmacokinetic, functional, structural and biochemical effects of single dose
Autor:
Jennifer L. Werkheiser, Maneesha Altekar, Lewis B. Kinter, Jane Stewart, Håkan H. A. S. Andersson, David Brott, Pam Campbell, Patricia Bentley, Russell D. J. Huby
Publikováno v:
Basicclinical pharmacologytoxicology. 111(6)
Centrally acting dopamine agonists (e.g. bromocriptine) and dopamine transport inhibitors (e.g. GBR12909) are known to inhibit oestradiol-induced prolactin release. The capacity of peripherally restricted compounds to do likewise, however, is unknown
Autor:
Jen Venzie, Pam Campbell, Lewis B. Kinter, Russell D. J. Huby, Jane Stewart, Håkan Andersson, David Brott, Patricia Bentley
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:203-204
Autor:
Yafei Chen, Russell Bialecki, Pamela Campbell, Harriet Kamendi, Patricia Bentley, Lewis B. Kinter, David Brott
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 64:e59