Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Patricia B. Gordon"'
Autor:
Anthony O. Beas, Patricia B. Gordon, Clara L. Prentiss, Carissa Perez Olsen, Matthew A. Kukurugya, Bryson D. Bennett, Susan M. Parkhurst, Daniel E. Gottschling
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).
Externí odkaz:
https://doaj.org/article/ccc42411f0664158949caf4ea685050d
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Hydrofluoric acid elicits cell cycle arrest through a mechanism that has long been presumed to be linked with the high affinity of fluoride to metals. However, we have recently found that the acid stress from fluoride exposure is sufficient to elicit
Externí odkaz:
https://doaj.org/article/3f5ab5f91bf94fa291452c028fc72623
Autor:
Kathryn D. Smith, Patricia B. Gordon, Alberto Rivetta, Scott A. Strobel, Clifford L. Slayman, Kenneth E. Allen, Tetyana Berbasova
Publikováno v:
Journal of Biological Chemistry. 290:19874-19887
Fluoride is a ubiquitous environmental toxin with which all biological species must cope. A recently discovered family of fluoride export (FEX) proteins protects organisms from fluoride toxicity by removing it from the cell. We show here that FEX pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c21b33d49ab3c675690c8e9e2595c0
https://doi.org/10.1074/jbc.m115.651976
https://doi.org/10.1074/jbc.m115.651976
Autor:
Sunitha Nallur, Patricia B. Gordon, Kathryn D. Smith, Susan Lori Tausta, Tetyana Berbasova, Taylor Sells, Scott A. Strobel
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177096 (2017)
PLoS ONE
PLoS ONE
The fluoride export protein (FEX) in yeast and other fungi provides tolerance to fluoride (F-), an environmentally ubiquitous anion. FEX efficiently eliminates intracellular fluoride that otherwise would accumulate at toxic concentrations. The FEX ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c69147ea52612024bde14f01617b6c
http://europepmc.org/articles/PMC5417652?pdf=render
http://europepmc.org/articles/PMC5417652?pdf=render
Autor:
Jared H. Davis, Patricia B. Gordon, Ronald R. Breaker, Sanshu Li, Scott A. Strobel, Kathryn D. Smith
Publikováno v:
Proceedings of the National Academy of Sciences. 110:19018-19023
Fluorine is an abundant element and is toxic to organisms from bacteria to humans, but the mechanisms by which eukaryotes resist fluoride toxicity are unknown. The Escherichia coli gene crcB was recently shown to be regulated by a fluoride-responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a15b0c444721dd02ebf9b424c23dba
https://doi.org/10.1073/pnas.1310439110
https://doi.org/10.1073/pnas.1310439110
Autor:
David J. Leffell, Susan T. Mayne, Leah M. Ferrucci, Annette M. Molinaro, Brenda Cartmel, Allen E. Bale, Patricia B. Gordon
Publikováno v:
The Journal of investigative dermatology, vol 132, iss 4
The Journal of investigative dermatology
The Journal of investigative dermatology
Basal cell carcinoma (BCC) incidence is increasing, particularly among adults under the age of 40 years. Pigment-related characteristics are associated with BCC in older populations, but epidemiologic studies among younger individuals and analyses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158c87a89062cba0ccec71fce51751c2
Autor:
Paul T. Spellman, Jon C. Aster, Yong Zou, Mimansa Sharma, Isaac M. Neuhaus, Charlotte M. Proby, Pui-Yan Kwok, Lakshmi Jakkula, Joe W. Gray, Stephen C. Blacklow, Kyunghee Park, Philip E. LeBoit, Joe S Hur, Laura J. Bayston, Zachary Sanborn, James E. Cleaver, Wilson Liao, Swapna S. Vemula, Theodora M. Mauro, Pierre P. Massion, Nicholas J. Wang, Andrew P. South, Jeffrey P. North, Allen E. Bale, Eric A. Collisson, Irene M. Leigh, Sally D. Pennypacker, Raymond J. Cho, Nam Huh, Sarah T. Arron, David Haussler, Kelly L. Arnett, Patricia B. Gordon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(43)
Squamous cell carcinomas (SCCs) are one of the most frequent forms of human malignancy, but, other than TP53 mutations, few causative somatic aberrations have been identified. We identified NOTCH1 or NOTCH2 mutations in ∼75% of cutaneous SCCs and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242d4f78e7880c188c67862a2cd12aa9
https://pubmed.ncbi.nlm.nih.gov/22006338
https://pubmed.ncbi.nlm.nih.gov/22006338
Autor:
Allison Hanlon, Patricia B. Gordon, Zhengqing Ouyang, Christopher Heffelfinger, Michael Snyder, Wei Zheng, Allen E. Bale, David J. Leffell, Anna K. Engberg, Hongyu Zhao
Publikováno v:
G3: Genes|Genomes|Genetics
Basal cell carcinomas (BCCs) are the most common cancers in the United States. The histologic appearance distinguishes several subtypes, each of which can have a different biologic behavior. In this study, global miRNA expression was quantified by hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd3ef7c14ee866dbf09662cf9b7fb8a
https://pubmed.ncbi.nlm.nih.gov/22384406
https://pubmed.ncbi.nlm.nih.gov/22384406
Autor:
Allen E. Bale, Brenda Cartmel, David J. Leffell, Susan T. Mayne, Leah M. Ferrucci, Annette M. Molinaro, Patricia B. Gordon
Publikováno v:
Cancer Prevention Research. 4:A83-A83
Background: Basal cell carcinoma (BCC), which accounts for 80% of non-melanoma skin cancers, is the most common cancer in the United States, with more than two million BCCs diagnosed annually. In recent decades, BCC incidence has been increasing, par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df30e3581c0e80525f336d03a957e330
https://doi.org/10.1158/1940-6207.prev-11-a83
https://doi.org/10.1158/1940-6207.prev-11-a83
Autor:
Tetyana Berbasova, Sunitha Nallur, Taylor Sells, Kathryn D Smith, Patricia B Gordon, Susan Lori Tausta, Scott A Strobel
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177096 (2017)
The fluoride export protein (FEX) in yeast and other fungi provides tolerance to fluoride (F-), an environmentally ubiquitous anion. FEX efficiently eliminates intracellular fluoride that otherwise would accumulate at toxic concentrations. The FEX ho
Externí odkaz:
https://doaj.org/article/c6f040db853447be8d324aa9bd394337