Výsledky vyhledávání - "Patricia A. Spera"

Caspase-8 and Caspase-3 Are Expressed by Different Populations of Cortical Neurons Undergoing Delayed Cell Death after Focal Stroke in the Rat

Autor: Giora Z. Feuerstein, Julie A. Ellison, Frank C. Barone, James J. Velier, Kristine K. Kikly, Patricia A. Spera

Publikováno v: The Journal of Neuroscience. 19:5932-5941

A number of studies have provided evidence that neuronal cell loss after stroke involves programmed cell death or apoptosis. In particular, recent biochemical and immunohistochemical studies have demonstrated the expression and activation of intracel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbe04a55457e13ba70325538b1e93ef
https://doi.org/10.1523/jneurosci.19-14-05932.1999

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Effect of Hypertonic Saline on Leukocyte Activity After Spinal Cord Injury

Autor: Ronald F. Tuma, William F. Young, Patricia A. Spera, Karl E. Arfors, Usha S. Vasthare

Publikováno v: Spine. 23:2444-2448

Study Design. The effect of intravenous administration of hypertonic saline on leukocyte adhesion after compression injury of the spinal cord was evaluated. Objectives. To investigate changes in leukocyte adhesion after spinal cord injury and to eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c4bdad48281292caea000509c18a34
https://doi.org/10.1097/00007632-199811150-00018

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Ischemic Preconditioning and Brain Tolerance: Temporal Histological and Functional Outcomes, Protein Synthesis Requirement, and Interleukin-1 Receptor Antagonist and Early Gene Expression

Autor: Frank C. Barone, Giora Z. Feuerstein, Raymond F. White, Julie A. Ellison, Xinkang Wang, R. William Currie, Patricia A. Spera

Publikováno v: Stroke. 29:1937-1951

Background and Purpose —A short duration of ischemia (ie, ischemic preconditioning [PC]) can provide significant brain protection to subsequent ischemic events (ie, ischemic tolerance [IT]). The present series of studies was conducted to characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22942720d9af49c1ccf335e2319f9f39
https://doi.org/10.1161/01.str.29.9.1937

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Osteopontin and its Integrin Receptor α v β 3 Are Upregulated During Formation of the Glial Scar After Focal Stroke

Autor: Frank C. Barone, Giora Z. Feuerstein, Xinkang Wang, Julie A. Ellison, Zdenka L. Jonak, Patricia A. Spera, James J. Velier

Publikováno v: Stroke. 29:1698-1707

Background and Purpose —Microglia and astrocytes in the peri-infarct region are activated in response to focal stroke. A critical function of activated glia is formation of a protective barrier that ultimately forms a new glial-limiting membrane. O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b16d62e80ffc4242afe6f3fd966f4b6
https://doi.org/10.1161/01.str.29.8.1698

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IL-10 reduces rat brain injury following focal stroke

Autor: Frank C. Barone, Giora Z. Feuerstein, Patricia A. Spera, Julie A. Ellison

Publikováno v: Neuroscience letters. 251(3)

The effects of the anti-inflammatory cytokine, IL-10, on brain injury following permanent focal ischemia were determined. Rats subjected to occlusion of the right middle cerebral artery (MCAO) were administered IL-10 (1 microg) centrally into the lat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71b52def90026b5debd3db71be8b98b
https://pubmed.ncbi.nlm.nih.gov/9726375

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