Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patricia A. Smanik"'
Autor:
M J Oglesbee, Ernest L. Mazzaferri, J E Trosko, Sissy M. Jhiang, Shunhua Xing, Patricia A. Smanik
Publikováno v:
Endocrinology. 137:1512-1519
Germline mutations of c-ret, encoding a receptor-type tyrosine kinase, were found to be associated with variants of multiple endocrine neoplasia type 2 (MEN2A, MEN2B), and familial medullary thyroid carcinoma. NIH/3T3 stable transfectants expressing
Publikováno v:
Cancer Letters. 78:69-76
In up to 25% of human papillary thyroid carcinomas (PCs), the oncogenic activation of ret results from the fusion of its tyrosine kinase domain with different unlinked amino-terminal sequences. Activation of this oncogene may be of prognostic signifi
Autor:
Kwon-Yul Ryu, Allan Siperstein, Quan-Yang Duh, Mariwil G. Wong, Patricia A. Smanik, Sissy M. Jhiang, Orlo H. Clark, Molly E. Senokozlieff, Ernest L. Mazzaferri
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 9(4)
The sodium iodide symporter (NIS) is the plasma membrane protein that mediates active iodide uptake into thyroid follicular cells. To investigate whether human NIS (hNIS) mRNA levels in papillary thyroid carcinomas (PCs) correlate with the ability of
An immunohistochemical study of Na+/I- symporter in human thyroid tissues and salivary gland tissues
Autor:
Ernest L. Mazzaferri, Je-Yoel Cho, Patricia A. Smanik, Kwon-Yul Ryu, Andrew H. Fischer, Violeta R. McGaughy, Barry R. DeYoung, Sissy M. Jhiang
Publikováno v:
Endocrinology. 139(10)
The human Na+/I- symporter (hNIS) is the plasma membrane protein that mediates active iodide uptake into several tissues, such as the thyroid and salivary glands. To study the distribution and cellular localization of the hNIS protein, we have genera
Autor:
Tara L. Furminger, Shunhua Xing, Qing-Rong Liu, Ernest L. Mazzaferri, Patricia A. Smanik, Sissy M. Jhiang, Kwon-Yul Ryu
Publikováno v:
Biochemical and biophysical research communications. 226(2)
The iodide concentrating activity of the thyroid gland is essential to the production of thyroid hormone and also provides a mechanism for the treatment of thyroid cancer by radioiodine ablation. We report here the nucleotide and amino acid sequence
Publikováno v:
Human molecular genetics. 4(12)
The ret/PTC oncogene, rearranged form of the ret proto-oncogene (c-ret), has been detected specifically in a minority of papillary thyroid carcinomas. Three forms of the ret/PTC oncogene have been identified; the two most common forms, ret/PTC-1 and
Autor:
Sissy M. Jhiang, Patricia A. Smanik, Ernest L. Mazzaferri, Linda Fithian, Jeffrey McGill, Qiang Tong
Publikováno v:
FEBS letters. 318(2)
A cDNA clone encoding a taurine transporter, designated HTAU, has been isolated from human thyroid. It contains an open reading frame encoding a protein of 619 amino acids with a calculated molecular weight of 69,675 Da. The predicted amino acid sequ