Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Patricia A. Preisig"'
Publikováno v:
Lab Animal. 46:290-294
Background Urine citrate is reabsorbed exclusively along the renal proximal tubule via the apical Na+-dicarboxylate cotransporter NaDC-1. We previously showed that an acid load in vivo and media acidification in vitro increase NaDC-1 activity through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c542c0f196d150815397183560e99ac9
http://hdl.handle.net/11591/392151
http://hdl.handle.net/11591/392151
Publikováno v:
Lab animal. 46(4)
There is a "village" of people impacting research reproducibility, such as funding panels, the IACUC and its support staff, institutional leaders, investigators, veterinarians, animal facilities, and professional journals. IACUCs can contribute to re
Publikováno v:
American Journal of Physiology-Renal Physiology. 293:F1054-F1064
Exposure to an acid load increases apical membrane Na+/H+ antiporter (NHE3) activity, a process that involves exocytic trafficking of the transporter to the apical membrane. We have previously shown that an intact microfilament structure is required
Autor:
Orson W. Moe, Patricia A. Preisig
Publikováno v:
Current Opinion in Nephrology & Hypertension. 15:419-424
Introduction Most species in the animal kingdom employ an apatitebased endo or exoskeleton, which mandates an obligatory turnover of calcium and phosphorus in the organism. If all the minerals from skeletal turnover could be completely captured and r
Autor:
Orson W. Moe, Patricia A. Preisig
Publikováno v:
Current Opinion in Nephrology & Hypertension. 14:368-372
Introduction Organ structure and function in present day organisms are the cumulative results of billions of years of evolution. Although they are not optimal, they are mostly adequate for our physiologic needs [1]. When placed against the time scale
Publikováno v:
American Journal of Physiology-Renal Physiology. 288:F732-F739
Endothelin-1 (ET-1) increases the activity of Na+/H+exchanger 3 (NHE3), the major proximal tubule apical membrane Na+/H+antiporter. This effect is seen in opossum kidney (OKP) cells expressing the endothelin-B (ETB) and not in cells expressing the en
Publikováno v:
Journal of Clinical Investigation. 114:1782-1789
Publikováno v:
Kidney International. 65:1320-1326
An autocrine role for endothelin-1 in the regulation of proximal tubule NHE3. Background Chronic metabolic acidosis leads to an increase in NHE3 activity that is mediated by endothelin-1 (ET-1) expression and activation of the proximal tubule endothe
Autor:
Joseph E. Zerwekh, Orson W. Moe, Charles Y. C. Pak, William L. Gitomer, Jamshid Amanzadeh, Moshe Levi, Patricia A. Preisig
Publikováno v:
Kidney International. 64(6):2142-2149
Effect of high protein diet on stone-forming propensity and bone loss in rats. Background High protein diets are believed to cause kidney stone formation and bone loss, but the mechanisms mediating these changes are unknown. The purpose of this study