Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Patricia A. Manderscheid"'
Autor:
Patricia A. Manderscheid, Robert H. Notter, Krishnan Raghavendran, Jadwiga D. Helinski, Paul R. Knight, Cristi J. Marschke, James A. Woytash, Bruce A. Davidson
Publikováno v:
Anesthesia & Analgesia. 101:1482-1489
Lung contusion affects 17%-25% of adult blunt trauma patients, and is the leading cause of death from blunt thoracic injury. A small animal model for isolated bilateral lung contusion has not been developed. We induced lung contusion in anesthetized
Publikováno v:
Photochemistry and Photobiology. 69:222-225
The role of the irradiation site in the induction of suppression of the contact hypersensitivity (CHS) response following photodynamic therapy (PDT) was examined in a murine model. Laser irradiation on the flanks of nontumor-bearing Photofrin-injecte
Autor:
Patricia Z. Manderscheid, Sangeeta Panicker, Demetria Kokoris, Henry P. Williams, Robert A. Frank
Publikováno v:
Pharmacology Biochemistry and Behavior. 42:771-779
The time course of cocaine-induced changes in self-stimulation thresholds were used to evaluate cocaine euphoria and dysphoria as a function of the chronicity of drug treatment, dosage level, and the spacing of injections. It was assumed that cocaine
Publikováno v:
Pharmacology Biochemistry and Behavior. 40:273-277
While some investigators have reported that cocaine increases response rates for brain stimulation reward, others have failed to demonstrate this effect. The present study was designed to evaluate the influence of stimulation parameters, dose of coca
Autor:
Krishnan Raghavendran, Robert H. Notter, Jadwiga D. Helinski, Cristi J. Marschke, Patricia A. Manderscheid, Paul R. Knight, James A. Woytash, Bruce A. Davidson
Publikováno v:
Shock (Augusta, Ga.). 24(2)
Lung contusion is the leading cause of death from blunt thoracic trauma in adults, but its mechanistic pathophysiology remains unclear. This study uses a recently developed rat model to investigate the evolution of inflammation and injury in isolated
Autor:
James A. Woytash, Patricia A. Manderscheid, Bruce A. Holm, Robert H. Notter, Barbara A. Mullan, Paul R. Knight, Bruce A. Davidson, Krishnan Raghavendran, Alan D. Hutson, Thomas A. Russo
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 289(1)
A model of aspiration lung injury was developed in WT C57BL/6 mice to exploit genetically modified animals on this background, i.e., MCP-1(−/−) mice. Mice were given intratracheal hydrochloric acid (ACID, pH 1.25), small nonacidified gastric part
Autor:
Patricia A. Manderscheid, Paul R. Knight, Ryan P. Bodkin, Thomas A. Russo, Erik Jensen, Bruce A. Davidson
Publikováno v:
Clinical and diagnostic laboratory immunology. 11(4)
The development of a nosocomial pneumonia is facilitated by alterations in host innate pulmonary antibacterial defenses following surgical trauma, which can result in decreased pulmonary bacterial clearance and increased morbidity and mortality. In a
Autor:
W. M. Klykylo, Brian J. McConville, Andrew B. Norman, Patricia Z. Manderscheid, K.W. Parker, Paul R. Sanberg, M H Fogelson
Publikováno v:
American Journal of Psychiatry. 148:793-794
In an open, nonblind study, 10 patients with Tourette's disorder who were being treated with haloperidol were videotaped before, while, and after chewing nicotine gum. The frequency of tics was reduced significantly during the 30-minute gum-chewing p
Publikováno v:
Life sciences. 44(21)
Animal studies suggest nicotine and cannabinoids may significantly enhance the therapeutic value of neuroleptics in motor disorders. This was recently demonstrated in humans by the finding that chewing nicotine gum produced striking relief from tics
Publikováno v:
Japanese Journal of Pharmacology. 43:221