Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Patricia A. Harper"'
Autor:
Patricia A. Harper, Tongtong Chen, Shinya Ito, Linda Sun, Pooja Dalvi, Mingdong Yang, Hitomi Hino
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:175-178
Paclitaxel, a mitotic inhibitor with anti-cancer effects, is dissolved in Cremophor EL (CrEL). However, peripheral neuropathy is a known side effect. As one of the mechanisms of the neuropathy, mitochondrial dysfunction has been proposed, while perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f7aae39ec4abd035738fb16068cd19
https://doi.org/10.1248/bpb.b19-00377
https://doi.org/10.1248/bpb.b19-00377
Autor:
Hitomi, Hino, Mingdong, Yang, Pooja, Dalvi, Tongtong, Chen, Linda, Sun, Patricia A, Harper, Shinya, Ito
Publikováno v:
Biologicalpharmaceutical bulletin. 43(1)
Paclitaxel, a mitotic inhibitor with anti-cancer effects, is dissolved in Cremophor EL (CrEL). However, peripheral neuropathy is a known side effect. As one of the mechanisms of the neuropathy, mitochondrial dysfunction has been proposed, while perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86a9b9c0ee5de9f42bec1b05a5e87288
https://pubmed.ncbi.nlm.nih.gov/31902922
https://pubmed.ncbi.nlm.nih.gov/31902922
Autor:
Guangju Zhai, Patricia E. Harper, Glynn Martin, Kensuke Hirasawa, M. Liu, Seyd Babak Razavi-Lopez, Erfan Aref-Eshghi, Proton Rahman, Guang Sun, Andrew Furey, Roger C. Green
Publikováno v:
The Journal of Rheumatology. 43:388-394
Objective.To compare SMAD3 gene expression between human osteoarthritic and healthy cartilage and to examine whether expression is regulated by the promoter DNA methylation of the gene.Methods.Human cartilage samples were collected from patients unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95065aa1b5508b4af909a6510f0ee29
https://doi.org/10.3899/jrheum.150609
https://doi.org/10.3899/jrheum.150609
Autor:
Ryan Potter, Jean McGowan-Jordan, Lucas Bronicki, Hussein Daoud, Erinija Pranckeviciene, Elizabeth Sinclair-Bourque, Amanda C. Smith, Leichelle Little, Landry Nfonsam, Mahdi Ghani, Patricia E. Harper, Caitlin Chisholm, Olga Jarinova, Audrey Schaffer
Publikováno v:
The Journal of molecular diagnostics : JMD. 21(4)
A cohort of 1242 individuals tested in a clinical diagnostic laboratory was used to test whether the filtering allele frequencies (FAFs)-based framework, recently recommended for MHY7-associated cardiomyopathy, is extendable to 45 cardiomyopathy gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b5e713606eff2e955ccdad5e2c2c64
https://pubmed.ncbi.nlm.nih.gov/31028938
https://pubmed.ncbi.nlm.nih.gov/31028938
Autor:
Rosanna Weksberg, Darci T. Butcher, Andrei L. Turinsky, Sean E. Egan, Mingdong Yang, Shinya Ito, Alex Wu, Wei Wang, Pooja Dalvi, Patricia A. Harper
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 307:E596-E610
The multidrug resistance efflux transporter ATP-binding cassette subfamily G member 2 (ABCG2) is not only overexpressed in certain drug-resistant cancers but is also highly expressed in the mammary gland during lactation, carrying xenobiotics and nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfd64f68b4d41251904ce00b753247b
https://doi.org/10.1152/ajpendo.00323.2014
https://doi.org/10.1152/ajpendo.00323.2014
Autor:
Andrew Furey, Glynn Martin, Weidong Zhang, Erfan Aref-Eshghi, Proton Rahman, Edward Randell, Guangju Zhai, Guang Sun, Patricia E. Harper, Sergei Likhodii, Roger C. Green
Publikováno v:
Metabolomics. 12
This study was to investigate how OA patients with metabolic syndrome (MetS) are different metabolically from OA patients without MetS components and healthy individuals. A two-stage case–control study design was utilized. Synovial fluid (SF) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed67c0745a11b1eedbda45a008317ae2
https://doi.org/10.1007/s11306-015-0937-x
https://doi.org/10.1007/s11306-015-0937-x
Autor:
Xiaoli Lu, Pooja Dalvi, David S. Riddick, Mingdong Yang, Jason Matthews, Patricia A. Harper, Douglas D. Ross, Shinya Ito, Alex Wu, Charles V. Clevenger
Publikováno v:
Molecular Pharmacology. 83:377-388
The multidrug transporter, breast cancer resistance protein, ABCG2, is up-regulated in certain chemoresistant cancer cells and in the mammary gland during lactation. We investigated the role of the lactogenic hormone prolactin (PRL) in the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a38363945d226b14eb208e466979db1
https://doi.org/10.1124/mol.112.082362
https://doi.org/10.1124/mol.112.082362
Autor:
Agnes L. Forgacs, Jason Matthews, Trine Celius, Patricia A. Harper, Raymond Lo, Timothy R. Zacharewski, Laura MacPherson, Edward Dere
Publikováno v:
Toxicology and Applied Pharmacology. 257:38-47
Genome-wide, promoter-focused ChIP-chip analysis of hepatic aryl hydrocarbon receptor (AHR) binding sites was conducted in 8-week old female C57BL/6 treated with 30 μg/kg/body weight 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) for 2 h and 24 h. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f151cee37169740388ab113796e7ea
https://doi.org/10.1016/j.taap.2011.08.016
https://doi.org/10.1016/j.taap.2011.08.016
Publikováno v:
American Journal of Epidemiology. 172:1000-1014
The risk of colorectal cancer associated with smoking is unclear and may be influenced by genetic variation in enzymes that metabolize cigarette carcinogens. The authors examined the colorectal cancer risk associated with smoking and 26 variants in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f6d07828eef9aef45ef332170e32f7
https://doi.org/10.1093/aje/kwq245
https://doi.org/10.1093/aje/kwq245
Autor:
Bernice Wang, Mingdong Yang, Haibo Xu, Patricia A. Harper, Douglas D. Ross, Kazuhiro Kosuge, Mika Yamamoto, Shinichiro Takahashi, Alex Wu, Shinya Ito, Kah Poh Tan, Jane MacAulay, Paul C. Boutros, Andrew I. Chuang
Publikováno v:
Molecular Pharmacology. 78:175-185
Breast cancer resistance protein (BCRP/ABCG2) is a membrane-bound efflux transporter important in cellular detoxification and multidrug resistance. Some aryl hydrocarbon receptor (AHR) agonists were reported to induce BCRP expression in human colon c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdb2ab70ae0d0df7c3e3e066f46ab96
https://doi.org/10.1124/mol.110.065078
https://doi.org/10.1124/mol.110.065078