Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Patricia A. Gonnella"'
Publikováno v:
Biomaterials
Human insulin-like growth factor-1 (IGF-1) plays important roles in development and regeneration of skeletal muscles and bones but requires daily injections or surgical implantation. Current clinical IGF-1 lacks e-peptide and is glycosylated, reducin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459876e148c3b12b3650afa91d62e5e8
https://pubmed.ncbi.nlm.nih.gov/31870566
https://pubmed.ncbi.nlm.nih.gov/31870566
Autor:
Patricia A. Gonnella, Todd G. Cook, Bakhtiyor Yakubov, Tim Lahm, Venkata Mangu, Peyman Habibi, Amanda Fisher, Steven M. Kawut, Lily Zeng, Yao Shi, Jiyoung Park, Henry Daniell
Publikováno v:
Biomaterials
Pulmonary arterial hypertension (PAH) is a deadly and uncurable disease characterized by remodeling of the pulmonary vasculature and increased pulmonary artery pressure. Angiotensin Converting Enzyme 2 (ACE2) and its product, angiotensin-(1–7) [ANG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56717c1491c72a674b7447fb47ed00d
https://doi.org/10.1016/j.biomaterials.2019.119750
https://doi.org/10.1016/j.biomaterials.2019.119750
Publikováno v:
Journal of Clinical Immunology. 29:434-443
Experimental autoimmune myocarditis (EAM) is mediated by myocardial infiltration by myosin-specific T cells secreting inflammatory cytokines.To clarify the role of cytokines in EAM, we compared STAT 6-deficient ((-/-)) with STAT 4(-/-) and wild-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e43662016ca289b22661cb8f2e52a76
https://doi.org/10.1007/s10875-009-9290-z
https://doi.org/10.1007/s10875-009-9290-z
Publikováno v:
Journal of Autoimmunity. 31:180-187
Toll-like receptors (TLR) are pattern recognition receptors that are an essential feature of host defense against pathogens. Expression of TLR-4 on dendritic cells was reported to be required for initiation of experimental autoimmune myocarditis (EAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2e983bdb03c4174e5a29537392e107
https://doi.org/10.1016/j.jaut.2008.06.002
https://doi.org/10.1016/j.jaut.2008.06.002
Publikováno v:
Journal of Autoimmunity. 23:193-200
IL-10 has been shown to be an important anti-inflammatory mediator that has both down-regulatory and immunomodulatory effects. Utilizing IL-10(-/-) mice we demonstrate the induction of low dose oral tolerance characterized by the up-regulation of TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88c167668d54c908db57c01ba080053
https://doi.org/10.1016/j.jaut.2004.08.001
https://doi.org/10.1016/j.jaut.2004.08.001
Publikováno v:
The Journal of Immunology. 170:2316-2322
The chemokine monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 have been shown to play an important role in the migration and trafficking of macrophages and Th1 effector cells in experimental autoimmune encephalomyelitis. Also, MCP-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65af894759f0a2c8cb5df393416c1f5e
https://doi.org/10.4049/jimmunol.170.5.2316
https://doi.org/10.4049/jimmunol.170.5.2316
Publikováno v:
Research in Immunology. 148:528-533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8314afb18b15b63d3f85fb4dce9350d6
https://doi.org/10.1016/s0923-2494(98)80146-6
https://doi.org/10.1016/s0923-2494(98)80146-6
Autor:
Patricia A. Gonnella, Patricia A. Nelson, Theresa L. Hoffer, Howard L. Weiner, Yevgenya Akselband
Publikováno v:
Annals of the New York Academy of Sciences. 778:358-361
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eebdfd6a44943096fbe7ab9388cc16e
https://doi.org/10.1111/j.1749-6632.1996.tb21143.x
https://doi.org/10.1111/j.1749-6632.1996.tb21143.x
Autor:
Howard L. Weiner, Patricia A. Nelson, Yevgenya Akselband, Ahmad Al-Sabbagh, Youhai H. Chen, Scott S. Zamvil, Susan M. Dearborn, Patricia A. Gonnella, Z. Jane Tian
Publikováno v:
Annals of the New York Academy of Sciences. 778:145-155
Oral administration of myelin antigens reduces the incidence and severity of EAE in rat and mouse models and decreases the frequency of MBP-reactive cells and the frequency of attacks in some patients with multiple sclerosis. Low-dose oral tolerance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608278fea13d301bcfa1691f05c52b73
https://doi.org/10.1111/j.1749-6632.1996.tb21123.x
https://doi.org/10.1111/j.1749-6632.1996.tb21123.x
Publikováno v:
Journal of Cell Science. 106:937-940
The role of class II major histocompatibility antigens in classical antigen-presenting cells has been described (Unanue (1984) Annu. Rev. Immunol. 2, 395–428; Watts and McConnell (1987) Rev. Immunol. 5, 461–475). Whether enterocytes, which also e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c6e24ae037f4981afa9d9c9eb0c934
https://doi.org/10.1242/jcs.106.3.937
https://doi.org/10.1242/jcs.106.3.937