Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Patricia A. Finn"'
Autor:
Yi-Shin Chang, Kai Huang, Jessica M Lee, Christen L Vagts, Christian Ascoli, Md-Ruhul Amin, Mahmood Ghassemi, Claudia M Lora, Russell Edafetanure-Ibeh, Yue Huang, Ruth A Cherian, Nandini Sarup, Samantha R Warpecha, Sunghyun Hwang, Rhea Goel, Benjamin A Turturice, Cody Schott, Montserrat Hernandez, Yang Chen, Julianne Jorgensen, Wangfei Wang, Mladen Rasic, Richard M Novak, Patricia W Finn, David L Perkins
Publikováno v:
eLife, Vol 13 (2024)
Background: End-stage renal disease (ESRD) patients experience immune compromise characterized by complex alterations of both innate and adaptive immunity, and results in higher susceptibility to infection and lower response to vaccination. This immu
Externí odkaz:
https://doaj.org/article/7079f825a3dd43fd8ab53c2f324b6355
Autor:
Christen L. Vagts, Yi-Shin Chang, Christian Ascoli, Jessica M. Lee, Kai Huang, Yue Huang, Ruth A. Cherian, Nandini Sarup, Samantha R. Warpecha, Russell Edafetanure-Ibeh, Md-Ruhul Amin, Tasmin Sultana, Mahmood Ghassemi, Nadera J. Sweiss, Richard Novak, David L. Perkins, Patricia W. Finn
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Background Individuals with sarcoidosis are at higher risk for infection owing to underlying disease pathogenesis and need for immunosuppressive treatment. Current knowledge as to how subjects with sarcoidosis respond to different forms of vaccinatio
Externí odkaz:
https://doaj.org/article/79fbfa4e161445099a271d51a0e70983
Autor:
Yi-Shin Chang, Stockton Mayer, Elizabeth S. Davis, Evelyn Figueroa, Paul Leo, Patricia W. Finn, David L. Perkins
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 1, Pp 76-84 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential for rapid transmission in congregate settings. We describe the multidisciplinary response to an outbreak of coronavirus disease (COVID-19) in a large homeless shelter in C
Externí odkaz:
https://doaj.org/article/7957cd04c0614582af3cf164eee079ff
Autor:
Christian Ascoli, Cody A. Schott, Yue Huang, Benjamin A. Turturice, Wangfei Wang, Naomi Ecanow, Nadera J. Sweiss, David L. Perkins, Patricia W. Finn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionIn sarcoidosis, peripheral lymphopenia and anergy have been associated with increased inflammation and maladaptive immune activity, likely promoting development of chronic and progressive disease. However, the molecular mechanisms that le
Externí odkaz:
https://doaj.org/article/5b1cf0d57fea42a1aa3ffbe103ee6255
Autor:
Kai Huang, Catherine Wang, Christen Vagts, Vanitha Raguveer, Patricia W. Finn, David L. Perkins
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Hyperactive and damaging inflammation is a hallmark of severe rather than mild Coronavirus disease 2019 (COVID-19). To uncover key inflammatory differentiators between severe and mild COVID-19, we applied an unbiased single-cell transcriptomic analys
Externí odkaz:
https://doaj.org/article/133e3aa188184a338192dc9d2c68cc2d
Autor:
Wangfei Wang, Anirban Sinha, René Lutter, Jie Yang, Christian Ascoli, Peter J. Sterk, Nicole K. Nemsick, David L. Perkins, Patricia W. Finn
Publikováno v:
Viruses, Vol 14, Iss 11, p 2444 (2022)
Asthma symptoms are often exacerbated by the common-cold-causing rhinovirus (RV). In this study, we characterized the temporal behavior of circulating exosomal microRNAs (ExoMiRNAs) in a longitudinal bi-phasic case-control study of mild asthmatics (n
Externí odkaz:
https://doaj.org/article/9ba183b3045e46819dba6ddec762764c
Autor:
Alex Agelidis, Benjamin A. Turturice, Rahul K. Suryawanshi, Tejabhiram Yadavalli, Dinesh Jaishankar, Joshua Ames, James Hopkins, Lulia Koujah, Chandrashekhar D. Patil, Satvik R. Hadigal, Evan J. Kyzar, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Israel Vlodavsky, Jin-ping Li, David L. Perkins, Patricia W. Finn, Deepak Shukla
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
The drive to withstand environmental stresses and defend against invasion is a universal trait extant in all forms of life. While numerous canonical signaling cascades have been characterized in detail, it remains unclear how these pathways interface
Externí odkaz:
https://doaj.org/article/2ffdf956e9364785bc5fbcaa308dd5a9
Autor:
Christen Vagts, Christian Ascoli, Dustin R. Fraidenburg, Robert P. Baughman, Yue Huang, Russell Edafetanure-Ibeh, Samreen Ahmed, Benjamin Levin, Yang Lu, David L. Perkins, Patricia W. Finn, Nadera J. Sweiss
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Introduction: Sarcoidosis is a T-helper cell mediated disease characterized by granulomatous inflammation. We posited that unsupervised clustering of various features in sarcoidosis would establish phenotypes associated with inflammatory activity mea
Externí odkaz:
https://doaj.org/article/d194f9af4ec344c69354acf45e531f02
Autor:
Benjamin A Turturice, Juliana Theorell, Mary Dawn Koenig, Lisa Tussing-Humphreys, Diane R Gold, Augusto A Litonjua, Emily Oken, Sheryl L Rifas-Shiman, David L Perkins, Patricia W Finn
Publikováno v:
eLife, Vol 10 (2021)
There are perinatal characteristics, such as gestational age, reproducibly associated with the risk for pediatric asthma. Identification of biologic processes influenced by these characteristics could facilitate risk stratification or new therapeutic
Externí odkaz:
https://doaj.org/article/202db176b8b247c2a0ab69d54362701e
Autor:
Melissa A. Nickles, Kai Huang, Yi-Shin Chang, Maria M. Tsoukas, Nadera J. Sweiss, David L. Perkins, Patricia W. Finn
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
In this study we analyzed gene co-expression networks of three immune-related skin diseases: cutaneous sarcoidosis (CS), discoid lupus erythematosus (DLE), and psoriasis. We propose that investigation of gene co-expression networks may provide insigh
Externí odkaz:
https://doaj.org/article/a87ea0641fbd42c5b8cef7f8f12ab09c