Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Patricia A. Cole"'
Autor:
Steven C. R. Williams, Ndaba Mazibuko, Owen O’Daly, Christian Zurth, Fiona Patrick, Christian Kappeler, Iris Kuss, Patricia E. Cole
Publikováno v:
Targeted Oncology. 18:403-413
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8161ede27709adfdfedfb939598ef719
https://doi.org/10.1007/s11523-023-00959-5
https://doi.org/10.1007/s11523-023-00959-5
Autor:
Cristian Constantinescu, David Alagille, Caroline Papin, Eiji Sunahara, Shuhei Ikeda, Tatsuki Koike, Maki Miyamoto, John Seibyl, Gilles Tamagnan, Olivier Barret, Thomas J. Morley, Krista Fowles, Patricia E. Cole, Takanobu Kuroita, Toshiya Nishi
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:1148-1156
Purpose Cholesterol 24-hydroxylase (CH24H) is a brain-specific enzyme that plays a major role in brain cholesterol homeostasis by converting cholesterol into 24S-hydroxycholesterol. The selective CH24H inhibitor soticlestat (TAK-935) is being pursued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3b49ad503abe1c9b276111d06b8346
https://doi.org/10.1007/s00259-021-05565-z
https://doi.org/10.1007/s00259-021-05565-z
Autor:
Anita T. Ton, Elaine M. Jagoda, Peter L. Choyke, Patricia E Cole, Olga Vasalatiy, Jyoti Roy, Falguni Basuli, Tim Phelps, Raffit Hassan, Urs B. Hagemann, Frank I. Lin, Karen Wong, Alan Cuthbertson
Publikováno v:
Cancer Biotherapy & Radiopharmaceuticals
Introduction: [227Th]Th-3,2-HOPO-MSLN-mAb, a mesothelin (MSLN)-targeted thorium-227 therapeutic conjugate, is currently in phase I clinical trial; however, direct PET imaging using this conjugate is technically challenging. Thus, using the same MSLN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2030106f82d422dd7da5c8c86391a0fd
https://doi.org/10.1089/cbr.2020.4492
https://doi.org/10.1089/cbr.2020.4492
Autor:
Elizabeth R. Gerstner, Jonathan G. Goldin, Timothy F. Cloughesy, Amy Barone, Jeffrey A. Bacha, W. K. Alfred Yung, David Leung, Patricia E Cole, Matthew S. Brown, Benjamin M. Ellingson, Martin J. van den Bent, Patrick Y. Wen, Howard Colman, Timothy J. Kaufmann, Jerrold L. Boxerman
Publikováno v:
Neuro Oncol
Neuro-Oncology, 23(2), 189-198. Oxford University Press
Neuro-oncology, vol 23, iss 2
Neuro-Oncology, 23(2), 189-198. Oxford University Press
Neuro-oncology, vol 23, iss 2
Determination of therapeutic benefit in intracranial tumors is intimately dependent on serial assessment of radiographic images. The Response Assessment in Neuro-Oncology (RANO) criteria were established in 2010 to provide an updated framework to bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a525c740874af8ad37fb3bc423f2ab6
https://doi.org/10.1093/neuonc/noaa253
https://doi.org/10.1093/neuonc/noaa253
Autor:
Benjamin M Ellingson, Elizabeth R Gerstner, Andrew B Lassman, Caroline Chung, Howard Colman, Patricia E Cole, David Leung, Joshua E Allen, Manmeet S Ahluwalia, Jerrold Boxerman, Matthew Brown, Jonathan Goldin, Edjah Nduom, Islam Hassan, Mark R Gilbert, Ingo K Mellinghoff, Michael Weller, Susan Chang, David Arons, Clair Meehan, Wendy Selig, Kirk Tanner, W K Alfred Yung, Martin van den Bent, Patrick Y Wen, Timothy F Cloughesy
Publikováno v:
Neuro Oncol
Neuro-oncology, vol 24, iss 8
Neuro-Oncology, 24(8), 1219-1229. Oxford University Press
Neuro-oncology, vol 24, iss 8
Neuro-Oncology, 24(8), 1219-1229. Oxford University Press
Imaging response assessment is a cornerstone of patient care and drug development in oncology. Clinicians/clinical researchers rely on tumor imaging to estimate the impact of new treatments and guide decision making for patients and candidate therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4049c6f96093e9e7806de96c81259463
https://europepmc.org/articles/PMC9340639/
https://europepmc.org/articles/PMC9340639/
Autor:
Linda N Broer, Daan G Knapen, Frans Valentijn Suurs, Ingrid Moen, Danique Giesen, Stijn J H Waaijer, Baard Indrevoll, Christine Ellingsen, Alexander Kristian, Alan S Cuthbertson, Derk-Jan A de Groot, Patricia E Cole, Elisabeth G.E. de Vries, Urs B Hagemann, Marjolijn N Lub - de Hooge
Publikováno v:
The Journal of Nuclear Medicine, 63(11), 1715-1721. SOC NUCLEAR MEDICINE INC
Rationale: Mesothelin targeted thorium-227 conjugate (227Th-MSLN) is a novel targeted alpha therapy developed to treat mesothelin overexpressing cancers. We radiolabeled the same antibody-chelator conjugate with zirconium-89 (89Zr-MSLN) to evaluate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94de19515ac6c14f110f71366cb79f2
https://doi.org/10.2967/jnumed.121.263079
https://doi.org/10.2967/jnumed.121.263079
Publikováno v:
Revue Medicale de Bruxelles. 39:47-49
Transcranial Direct Current Stimulation (tDCS) is a cheap, easy to use, and relatively safe noninvasive brain stimulation technique. It is increasingly used in several indications in psychiatry and neurology, mainly for depression, chronic pain and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c06180de2b6325e473ffb164e099625
https://doi.org/10.30637/2018.17-106
https://doi.org/10.30637/2018.17-106
Autor:
Steven Einstein, Patricia E. Cole
Imaging biomarkers are a valuable tool in attaining the key objectives of drug development. This chapter focuses on PET/SPECT and MRI-derived biomarkers that are currently used in CNS drug development decision-making. It also profiles additional adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afdbb44661940aeacaf0d29d3a49fe4f
https://doi.org/10.1016/b978-0-12-803161-2.00009-6
https://doi.org/10.1016/b978-0-12-803161-2.00009-6
Autor:
Barry D. Greenberg, Linda J. Van Eldik, Reinhold Mueller, Dominik Feuerbach, Richard Margolin, Lisa J. Bain, Patricia E. Cole, Maria C. Carrillo, Richard M. Ransohoff, Nick Kozauer, Donna M. Wilcock, Matthew E. Kennedy, James Hendrix, Kelly R. Bales, José Luis Molinuevo
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
The Alzheimer's Association's Research roundtable met in April 2015 to explore the role of neuroinflammatory mechanisms in the progression of Alzheimer's disease (AD). The ability of innate immune cells, particularly microglia and astrocytes, to medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd09dd9d9c7db5d2860b721c340a777
Autor:
Clement J. Grassi, John F. Cardella, Ziv J. Haskal, Anne C. Roberts, Calvin D. Neithamer, Steven B. Oglevie, Louis G. Martin, Steven G. Meranze, Timothy L. Swan, David Sacks, Patricia E. Cole, Richard B. Towbin, Curtis A. Lewis, Mark I. Silverstein, Alain T. Drooz, Timothy C. McCowan
Publikováno v:
Journal of Vascular and Interventional Radiology. 27:1-7
Ziv J. Haskal, MD, Louis Martin, MD, John F. Cardella, MD, Patricia E. Cole, PhD, MD, Alain Drooz, MD,Clement J. Grassi, MD, Timothy C. McCowan, MD, Steven G. Meranze, MD, Calvin D. Neithamer, MD,Steven B. Oglevie, MD, Anne C. Roberts, MD, David Sack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5830baf1eb7c8237df09e74bfce6e406
https://doi.org/10.1016/j.jvir.2015.09.018
https://doi.org/10.1016/j.jvir.2015.09.018