Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Patricia A. Clow"'
Autor:
Patricia A. Clow, Menghan Du, Nathaniel Jillette, Aziz Taghbalout, Jacqueline J. Zhu, Albert W. Cheng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Three-dimensional (3D) structures of the genome are dynamic, heterogeneous and functionally important. Here the authors present a CRISPR-based approach for labeling the genome at multiple nonrepetitive loci in living cells and to image chromatin loop
Externí odkaz:
https://doaj.org/article/e739a9d4c7614d4c8e8421cc2d63189e
Autor:
Roel G.W. Verhaak, Albert W. Cheng, Patricia A. Clow, Nathaniel Jillette, Sunit Das, Qianru Yu, Megan L. Costa, Samirkumar B. Amin, Kevin C. Johnson, Dacheng Zhao, Hoon Kim, Molly Guthrie, Amit D. Gujar, Eunhee Yi
Supplementary Figures 1-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23501318d0da2a1f2a732924ae33fc98
https://doi.org/10.1158/2159-8290.22540790.v1
https://doi.org/10.1158/2159-8290.22540790.v1
Autor:
Roel G.W. Verhaak, Albert W. Cheng, Patricia A. Clow, Nathaniel Jillette, Sunit Das, Qianru Yu, Megan L. Costa, Samirkumar B. Amin, Kevin C. Johnson, Dacheng Zhao, Hoon Kim, Molly Guthrie, Amit D. Gujar, Eunhee Yi
Oncogenic extrachromosomal DNA elements (ecDNA) play an important role in tumor evolution, but our understanding of ecDNA biology is limited. We determined the distribution of single-cell ecDNA copy number across patient tissues and cell line models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a88643c243e39b9460b64613fae1d5b7
https://doi.org/10.1158/2159-8290.c.6549473.v1
https://doi.org/10.1158/2159-8290.c.6549473.v1
Autor:
Amit D. Gujar, Nathaniel Jillette, Hoon Kim, Molly Guthrie, Kevin C. Johnson, Sunit Das, Roel G.W. Verhaak, Dacheng Zhao, Samirkumar B. Amin, Eun Hee Yi, Albert W. Cheng, Qianru Yu, Megan L Costa, Patricia A. Clow
Publikováno v:
Cancer Discov
Oncogenic extrachromosomal DNA elements (ecDNA) play an important role in tumor evolution, but our understanding of ecDNA biology is limited. We determined the distribution of single-cell ecDNA copy number across patient tissues and cell line models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0978dd72b309d3b09a1b0d1136f07bae
https://pubmed.ncbi.nlm.nih.gov/35140176
https://pubmed.ncbi.nlm.nih.gov/35140176
Autor:
Amit D. Gujar, Patricia A. Clow, Samirkumar B. Amin, Albert W. Cheng, Eun Hee Yi, Molly Guthrie, Kevin C. Johnson, Sunit Das, Hoon Kim, Roel G.W. Verhaak
Oncogenic extrachromosomal DNA elements (ecDNAs) promote intratumoral heterogeneity, creating a barrier for successful cancer treatments. The underlying mechanisms are poorly understood and studies are hampered in part by a lack of adequate tools ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927b5e26eea403445e0cd48eb3802f01
https://doi.org/10.1101/2020.10.20.335216
https://doi.org/10.1101/2020.10.20.335216
Autor:
Patricia A. Clow, Menghan Du, Nathaniel Jillette, Aziz Taghbalout, Jacqueline J. Zhu, Albert W. Cheng
Three-dimensional (3D) structures of the genome are dynamic, heterogeneous and functionally important. Live cell imaging has become the leading method for chromatin dynamics tracking. However, existing CRISPR- and TALE-based genomic labeling techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e4f040663b8103b84ab5e75e77518a
https://doi.org/10.1101/2020.03.03.974923
https://doi.org/10.1101/2020.03.03.974923
Autor:
Nathaniel Jillette, Kevin M. Johnson, Sunit Das, Amit D. Gujar, Dacheng Zhao, Albert W. Cheng, Roel G.W. Verhaak, Samirkumar B. Amin, Eun Hee Yi, Patricia A. Clow, Hoon Kim, Molly Guthrie
Publikováno v:
Neuro-Oncology. 23:vi20-vi20
Oncogenic extrachromosomal DNA elements (ecDNAs) promote intratumoral heterogeneity, creating a barrier for successful cancer treatments. The underlying mechanisms are poorly understood and studies are hampered in part by a lack of adequate tools ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ddca3a11b71d4bc5e0d8492525f3f4
https://doi.org/10.1093/neuonc/noab196.072
https://doi.org/10.1093/neuonc/noab196.072
Autor:
Brandon D. Lawrence, Nikolay O. Bukanov, Bruce L. Roberts, Oxana Ibraghimov-Beskrovnaya, William R. Dackowski, Patricia A. Clow, Hervé Husson, Katherine W. Klinger
Publikováno v:
Human Molecular Genetics. 11:923-936
Polycystin-1 is a protein mutated in the majority of cases of autosomal dominant polycystic kidney disease (ADPKD), but its role in the molecular pathway of tubulogenesis and cystogenesis is not understood. To define the role of polycystin-1 during d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee54ef97d3fdc09032c925ba0037c23
https://doi.org/10.1093/hmg/11.8.923
https://doi.org/10.1093/hmg/11.8.923
Publikováno v:
Development. 127:2715-2728
During cell sorting in Dictyostelium, we observed that GFP-tagged prestalk cells (ecmAO-expressing cells) moved independently and directionally to form a cluster. This is consistent with a chemotaxis model for cell sorting (and not differential adhes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046a395afea73eb1a768b130498bcb7d
https://doi.org/10.1242/dev.127.12.2715
https://doi.org/10.1242/dev.127.12.2715
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 39(5)
Multiple studies in the general population have shown cardioprotective and survival benefits associated with dietary fish intake, but little is known about outcomes associated with dietary fish intake in patients with chronic renal failure. We invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9095ed9cfeac38e9a938ec88270b41f0
https://pubmed.ncbi.nlm.nih.gov/11979345
https://pubmed.ncbi.nlm.nih.gov/11979345