Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Patricia A. Baxter"'
Autor:
Huiyuan Zhang, Yuchen Du, Lin Qi, Sophie Xiao, Frank K. Braun, Mari Kogiso, Yulun Huang, Frank Huang, Aalaa Abdallah, Milagros Suarez, Sekar Karthick, Nabil M. Ahmed, Vita S. Salsman, Patricia A. Baxter, Jack M. Su, Daniel J. Brat, Paul L. Hellenbeck, Wan-Yee Teo, Akash J. Patel, Xiao-Nan Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Animal models representing different molecular subtypes of glioblastoma multiforme (GBM) is desired for developing new therapies. SVV-001 is an oncolytic virus selectively targeting cancer cells. It’s capacity of passing through
Externí odkaz:
https://doaj.org/article/f02330a7f677428e957a5b658a166efc
Autor:
Mari Kogiso, Lin Qi, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Lei Guo, Yulun Huang, Wan-Yee Teo, Holly Lindsay, Sibo Zhao, Sarah G. Injac, Zhen Liu, Vidya Mehta, Diep Tran, Feng Li, Patricia A. Baxter, Jack M. Su, Laszlo Perlaky, D. Williams Parsons, Murali Chintagumpala, Adekunle Adesina, Yongcheng Song, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101368- (2022)
Clinical outcomes in patients with WHO grade II/III astrocytoma, oligodendroglioma or secondary glioblastoma remain poor. Isocitrate dehydrogenase 1 (IDH1) is mutated in > 70% of these tumors, making it an attractive therapeutic target. To determine
Externí odkaz:
https://doaj.org/article/caa882369eb742c39053f6d150c8b83b
Autor:
Robert J. Wechsler-Reya, Jill P. Mesirov, Marcel Kool, Pablo Tamayo, Stefan M. Pfister, Eliezer M. Van Allen, Michael L. Levy, John R. Crawford, Denise Malicki, Shareef A. Nahas, David P. Dimmock, Terence C. Wong, Matija Snuderl, Iris Reyes, James M. Olson, Xiao-Nan Li, Yoon-Jae Cho, Till Milde, Kristiina Vuori, Michael E. Berens, Jacob J. Henderson, Patricia A. Baxter, Yuchen Du, Mari Kogiso, Lin Qi, Jonas Ecker, Jonathan Serrano, Susanne Gröbner, Brendan Reardon, Huriye Seker-Cin, Darren Finlay, Yoko T. Udaka, Sameerah Wahab, Silvia K. Tacheva-Grigorova, Lianne Q. Chau, Alexandra Garancher, James Jensen, Sebastian Brabetz, Edwin F. Juarez, Jessica M. Rusert
Supplementary Tables 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e0acfb93f88ece6d7d741e6519b013
https://doi.org/10.1158/0008-5472.22426581
https://doi.org/10.1158/0008-5472.22426581
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Purpose: Pediatric glioblastoma multiforme (pGBM) is a highly aggressive tumor in need of novel therapies. Our objective was to demonstrate the therapeutic efficacy of MLN8237 (alisertib), an orally available selective inhibitor of Aurora A kinase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add973a53fa03709cc14fba8c29ebe20
https://doi.org/10.1158/1078-0432.c.6526046
https://doi.org/10.1158/1078-0432.c.6526046
Autor:
Ira J. Dunkel, Maryam Fouladi, Arzu Onar-Thomas, Clinton F. Stewart, Matthias A. Karajannis, Angela J. Waanders, Lindsey Hoffman, Kathleen Dorris, Andrew Bukowinski, Eugene I. Hwang, Patricia A. Baxter, Tina Young Poussaint, Haitao Pan, Tong Lin, Olivia Campagne, Christine Fuller, Mariko D. DeWire
Purpose:Genomic aberrations in cell cycle and PI3K pathways are commonly observed in pediatric brain tumors. This study determined the MTD/recommended phase II dose (RP2D) of ribociclib and everolimus and characterized single-agent ribociclib concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127378820648ed2c11e8fe7ab202ca31
https://doi.org/10.1158/1078-0432.c.6530841
https://doi.org/10.1158/1078-0432.c.6530841
Autor:
Robert J. Wechsler-Reya, Jill P. Mesirov, Marcel Kool, Pablo Tamayo, Stefan M. Pfister, Eliezer M. Van Allen, Michael L. Levy, John R. Crawford, Denise Malicki, Shareef A. Nahas, David P. Dimmock, Terence C. Wong, Matija Snuderl, Iris Reyes, James M. Olson, Xiao-Nan Li, Yoon-Jae Cho, Till Milde, Kristiina Vuori, Michael E. Berens, Jacob J. Henderson, Patricia A. Baxter, Yuchen Du, Mari Kogiso, Lin Qi, Jonas Ecker, Jonathan Serrano, Susanne Gröbner, Brendan Reardon, Huriye Seker-Cin, Darren Finlay, Yoko T. Udaka, Sameerah Wahab, Silvia K. Tacheva-Grigorova, Lianne Q. Chau, Alexandra Garancher, James Jensen, Sebastian Brabetz, Edwin F. Juarez, Jessica M. Rusert
Supplementary Figures 1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d9d86caa17333c401c4162c15420ff
https://doi.org/10.1158/0008-5472.22426584
https://doi.org/10.1158/0008-5472.22426584
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Supplementary Figure S1-S3 Figure S1. Anti-proliferative effects of MLN8237 on pGBM cell lines. Paired monolayer (Mono) and neurosphere (NS) of IC-4687GBM, IC-3752GBM and ICR0315GBM were seeded at 2,000 cells/well and exposed to MLN8237 (1 - 4,000 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf825c071ffe844120a4e784048d90e
https://doi.org/10.1158/1078-0432.22465520.v1
https://doi.org/10.1158/1078-0432.22465520.v1
Autor:
Robert J. Wechsler-Reya, Jill P. Mesirov, Marcel Kool, Pablo Tamayo, Stefan M. Pfister, Eliezer M. Van Allen, Michael L. Levy, John R. Crawford, Denise Malicki, Shareef A. Nahas, David P. Dimmock, Terence C. Wong, Matija Snuderl, Iris Reyes, James M. Olson, Xiao-Nan Li, Yoon-Jae Cho, Till Milde, Kristiina Vuori, Michael E. Berens, Jacob J. Henderson, Patricia A. Baxter, Yuchen Du, Mari Kogiso, Lin Qi, Jonas Ecker, Jonathan Serrano, Susanne Gröbner, Brendan Reardon, Huriye Seker-Cin, Darren Finlay, Yoko T. Udaka, Sameerah Wahab, Silvia K. Tacheva-Grigorova, Lianne Q. Chau, Alexandra Garancher, James Jensen, Sebastian Brabetz, Edwin F. Juarez, Jessica M. Rusert
Medulloblastoma is among the most common malignant brain tumors in children. Recent studies have identified at least four subgroups of the disease that differ in terms of molecular characteristics and patient outcomes. Despite this heterogeneity, mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22432e8f22e80af772f660919f855f78
https://doi.org/10.1158/0008-5472.c.6512388
https://doi.org/10.1158/0008-5472.c.6512388
Autor:
Ira J. Dunkel, Maryam Fouladi, Arzu Onar-Thomas, Clinton F. Stewart, Matthias A. Karajannis, Angela J. Waanders, Lindsey Hoffman, Kathleen Dorris, Andrew Bukowinski, Eugene I. Hwang, Patricia A. Baxter, Tina Young Poussaint, Haitao Pan, Tong Lin, Olivia Campagne, Christine Fuller, Mariko D. DeWire
Pharmacokinetic Data Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf0b152a26b965d8f9bd68e7508f5a1
https://doi.org/10.1158/1078-0432.22482162
https://doi.org/10.1158/1078-0432.22482162
Autor:
Sibo Zhao, Jia Li Li, Huiyuan Zhang, Lin Qi, Yuchen Du, Mari Kogiso, Frank K Braun, Wan-Yee Teo, Holly Lindsay, Patricia A Baxter, Jack M Su, Adekunle Adesina, Sophie Xiao, Clifford Stephan, Stewart G Goldman, Peter J A Davies, Tsz-Kwong Man, Yun Huang, Yongcheng Song, Deqiang Sun, Xiao-Nan Li
Publikováno v:
Neuro-Oncology. 24:vii124-vii125
Ependymoma (EPN) is the third most common brain tumor in children and frequently recurs. Here, we report an integrated longitudinal analysis of epigenetic, genetic and tumorigenic changes in 30 patient-matched repeated relapses obtained from 10 pedia