Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Patricia A D'Amore"'
Autor:
Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract The endothelial glycocalyx, located at the luminal surface of the endothelium, plays an important role in the regulation of leukocyte adhesion, vascular permeability, and vascular homeostasis. Endomucin (EMCN), a component of the endothelial
Externí odkaz:
https://doaj.org/article/f866f4dfaaaf46d7b2fa5d0f1a92f343
Autor:
Tony E Walshe, Magali Saint-Geniez, Arindel S R Maharaj, Eiichi Sekiyama, Angel E Maldonado, Patricia A D'Amore
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5149 (2009)
Pericyte-endothelial cell (EC) interactions are critical to both vascular development and vessel stability. We have previously shown that TGF-beta signaling between EC and mural cells participates in vessel stabilization in vitro. We therefore invest
Externí odkaz:
https://doaj.org/article/e349d0a04e0b48aa8b3950c7983ccb0b
Autor:
Magali Saint-Geniez, Arindel S R Maharaj, Tony E Walshe, Budd A Tucker, Eiichi Sekiyama, Tomoki Kurihara, Diane C Darland, Michael J Young, Patricia A D'Amore
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3554 (2008)
Vascular endothelial growth factor (VEGF) is well known for its role in normal and pathologic neovascularization. However, a growing body of evidence indicates that VEGF also acts on non-vascular cells, both developmentally as well as in the adult. I
Externí odkaz:
https://doaj.org/article/bead3d11b19c41c68a74e8e7a509f97c
Autor:
Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ef97b5cde9c343d295b5fbf0c2c25d32
Autor:
Cindy Park-Windhol, Yin Shan Ng, Jinling Yang, Vincent Primo, Magali Saint-Geniez, Patricia A. D’Amore
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/94659447fca44762934706f78bb20464
Autor:
Patricia A. D’Amore, Pilar Alcaide
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
Cardiac repair following ischemic injury is indispensable for survival and requires a coordinated cellular response involving the mobilization of immune cells from the secondary lymphoid organs to the site of damage. Efferocytosis, the engulfment of
Externí odkaz:
https://doaj.org/article/86c510a2865e4782b1f5cc4409be20e4
Autor:
Issahy Cano, Zhengping Hu, Dina B. AbuSamra, Magali Saint-Geniez, Yin Shan Eric Ng, Pablo Argüeso, Patricia A. D’Amore
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Galectin-3 (Gal3) is a carbohydrate-binding protein reported to promote angiogenesis by influencing vascular endothelial growth factor-A receptor 2 (VEGFR2) signal transduction. Here we evaluated whether the ability of Gal3 to function as an angiogen
Externí odkaz:
https://doaj.org/article/84a4bf57a94d4616893c2374dcd0a098
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The endothelial glycocalyx is a negatively charged, carbohydrate-rich structure that arises from the luminal surface of the vascular endothelium and is comprised of proteoglycans, glycoproteins, and glycolipids. The glycocalyx, which sits at the inte
Externí odkaz:
https://doaj.org/article/9e645ece00334a7e931be0dea8a9c42a
Autor:
Xionggao Huang, Guohong Zhou, Wenyi Wu, Yajian Duan, Gaoen Ma, Jingyuan Song, Ru Xiao, Luk Vandenberghe, Feng Zhang, Patricia A. D’Amore, Hetian Lei
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Abnormal angiogenesis causes many ocular diseases. Here the authors employ CRISPR/Cas9 gene editing technology to silence VEGFR2, a major regulator of angiogenesis, in retinal endothelium and abrogate angiogenesis in the mouse models of oxygen-induce
Externí odkaz:
https://doaj.org/article/f981fc904c1b403e9521fe12e9013ee3
Autor:
Alisar Zahr, Pilar Alcaide, Jinling Yang, Alexander Jones, Meredith Gregory, Nathaniel G. dela Paz, Sunita Patel-Hett, Tania Nevers, Adarsha Koirala, Francis W. Luscinskas, Magali Saint-Geniez, Bruce Ksander, Patricia A. D’Amore, Pablo Argüeso
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Endomucin is expressed by endothelial cells that line postcapillary venules—the site of leukocyte recruitment during inflammation. Zahr et al.show that endomucin is an anti-adhesive molecule that is downregulated by the cytokine TNF-a and thereby h
Externí odkaz:
https://doaj.org/article/6861100b28e4491db16608726f0aa7d8