Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Patricia A, Goodman"'
Autor:
Pamela J Skinner, Hyeon O Kim, Damani Bryant, Nikilyn J Kinzel, Cavan Reilly, Suzette A Priola, Anne E Ward, Patricia A Goodman, Katherine Olson, Davis M Seelig
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131993 (2015)
Prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy in cattle, and scrapie in sheep are fatal neurodegenerative diseases for which there is no effective treatment. The pathology of these diseases involves the
Externí odkaz:
https://doaj.org/article/ff529682102349ca81df3b8145aeb0f7
Publikováno v:
Prion
Prion diseases, or transmissible spongiform encephalopathies (TSEs) are progressive, fatal neurodegenerative diseases with no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cellular pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f28bdbca8575716d723b1dc54e5bb97
http://europepmc.org/articles/PMC4981202
http://europepmc.org/articles/PMC4981202
Publikováno v:
EBioMedicine, Vol 1, Iss 1, Pp 16-28 (2014)
EBioMedicine
EBioMedicine
The identification of SYK as a molecular target in B-lineage leukemia/lymphoma cells prompted the development of SYK inhibitors as a new class of anti-cancer drug candidates. Here we report that induction of the SYK gene expression in human cells cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2a57fbca3db1dfbb86599d8d5ccd2b
http://www.sciencedirect.com/science/article/pii/S2352396414000218
http://www.sciencedirect.com/science/article/pii/S2352396414000218
Publikováno v:
Procedia Food Science. 1:1895-1900
“Education for Employment” (EFE) is a program funded by the Canadian International Development Agency (CIDA) and administered through the Association of Canadian Community Colleges (ACCC). It is directed towards providing post-secondary education
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945ab828d15129cc5d7b7d63c5236501
https://doi.org/10.1016/j.profoo.2011.09.278
https://doi.org/10.1016/j.profoo.2011.09.278
Autor:
Patricia A. Goodman, Hyeon O. Kim, Pamela J. Skinner, Davis M. Seelig, Cavan S. Reilly, Anne Ward, Katherine Olson, Nikilyn J. Kinzel, Suzette A. Priola, Damani Bryant
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131993 (2015)
PLoS ONE
PLoS ONE
Prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy in cattle, and scrapie in sheep are fatal neurodegenerative diseases for which there is no effective treatment. The pathology of these diseases involves the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248d6383ca61b861ff5850e75ba18b1d
http://europepmc.org/articles/PMC4489745?pdf=render
http://europepmc.org/articles/PMC4489745?pdf=render
Publikováno v:
Oncogene. 22:2504-2514
Sequence analysis of the noncoding first exon (exon 1) of the Syk gene demonstrated the presence of a previously cloned CpG island (GenBank #Z 65706). Transient transfection analysis in Daudi cells demonstrated promoter activity (18-fold increase ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e449d4e9d02f8a89566f6dd0c29a7f
https://doi.org/10.1038/sj.onc.1206313
https://doi.org/10.1038/sj.onc.1206313
Publikováno v:
European Journal of Haematology. 70:156-171
Fas (APO-1/CD95) is a 45-kDa membrane protein which regulates apoptosis in many lymphoid cell types. In the present study, FAS expression was examined in primary leukemic cells from infants with acute lymphoblastic leukemia (ALL). The cells were resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::616ff415868343dd3ad52eec9abb8017
https://doi.org/10.1034/j.1600-0609.2003.00024.x
https://doi.org/10.1034/j.1600-0609.2003.00024.x
Publikováno v:
Leukemia & Lymphoma. 43:2355-2362
Janus tyrosine kinase 3 (JAK3) is one of several key regulatory enzymes in B-cell precursors which is highly conserved between multiple species. The gene for Jak3 has been mapped to human chromosome 19p12-13.1 and encompasses 23 exons. Constitutively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6681e324d51e6f18db81e7dc2497ee46
https://doi.org/10.1080/1042819021000040062
https://doi.org/10.1080/1042819021000040062
Publikováno v:
Oncogene. 20:3969-3978
The cytoplasmic spleen tyrosine kinase (SYK) is a key regulator of signal transduction events, apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11f8390497b832093d6169d436e5795
https://doi.org/10.1038/sj.onc.1204515
https://doi.org/10.1038/sj.onc.1204515
Publikováno v:
Journal of Surgical Oncology. 64:27-31
Background Seromas of the axillary space following breast surgery can lead to significant morbidity and delay in the initiation of adjuvant therapy. A prospective, randomized study was undertaken to evaluate the effect of bovine spray thrombin on ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d704a7e7f731bb63cb2818a555196ff5
https://doi.org/10.1002/(sici)1096-9098(199701)64:1<27::aid-jso6>3.0.co
https://doi.org/10.1002/(sici)1096-9098(199701)64:1<27::aid-jso6>3.0.co