Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Patricia DeInnocentes"'
Autor:
Eric J. Fish, Esther Gisela Martinez‐Romero, Patricia DeInnocentes, Jey W. Koehler, Nripesh Prasad, Annette N. Smith, Richard Curt Bird
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 3, Pp 1282-1290 (2020)
Abstract Background Differentiating benign from canine malignant mammary tumors requires invasive surgical biopsy. Circulating microRNAs (miRNA) may represent promising minimally invasive cancer biomarkers in people and animals. Objectives To evaluat
Externí odkaz:
https://doaj.org/article/cf10aec3449f4f05b23baf06fc811e60
Autor:
Eric J. Fish, Kristopher J. Irizarry, Patricia DeInnocentes, Connor J. Ellis, Nripesh Prasad, Anthony G. Moss, R. Curt Bird
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-20 (2018)
Abstract Background Breast (mammary) cancers in human (BC) and canine (CMT) patients share clinical, pathological, and molecular similarities that suggest dogs may be a useful translational model. Many cancers, including BC, shed exosomes that contai
Externí odkaz:
https://doaj.org/article/e0f4485dbf774a1aaa7a649bb8476539
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 57:519-530
The cyclin-dependent kinase inhibitors (CKIs) belong to a group of key cell cycle proteins that regulate important cancer drug targets such as the cyclin/CDK complexes. Gene defects in the INK4A/B CKI tumor suppressor locus are frequently associated
Autor:
Annette N. Smith, Esther Gisela Martinez‐Romero, Richard C. Bird, Jey W. Koehler, Eric J. Fish, Patricia DeInnocentes, Nripesh Prasad
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 3, Pp 1282-1290 (2020)
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Background Differentiating benign from canine malignant mammary tumors requires invasive surgical biopsy. Circulating microRNAs (miRNA) may represent promising minimally invasive cancer biomarkers in people and animals. Objectives To evaluate the ser
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 57(5)
The cyclin-dependent kinase inhibitors (CKIs) belong to a group of key cell cycle proteins that regulate important cancer drug targets such as the cyclin/CDK complexes. Gene defects in the INK4A/B CKI tumor suppressor locus are frequently associated
Autor:
Patricia DeInnocentes, Kristopher J. L. Irizarry, R. Curt Bird, Connor J. Ellis, Nripesh Prasad, Eric J. Fish, Anthony G. Moss
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-20 (2018)
BMC Cancer
BMC Cancer
Background Breast (mammary) cancers in human (BC) and canine (CMT) patients share clinical, pathological, and molecular similarities that suggest dogs may be a useful translational model. Many cancers, including BC, shed exosomes that contain microRN
Autor:
E. Gisela Martinez-Romero, Annette N. Smith, Farruk M. Lutful Kabir, Allison E. Church Bird, Patricia DeInnocentes, Bruce F. Smith, R. Curtis Bird
Publikováno v:
Journal of Veterinary Science
Breast cancer is among the most common malignancies affecting women and reproductively intact female dogs, resulting in death from metastatic disease if not treated effectively. To better manage the disease progression, canine mammary tumor (CMT) cel
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 54(9)
p16 is an important tumor suppressor gene encoded by the INK4A/ARF/INK4B gene locus that is conserved in humans, rodents, and canids. p16 regulates cell cycle in early G1 phase inhibiting transition out of cell cycle from G1/S phase by regulating a m
Publikováno v:
Journal of Cellular Biochemistry. 116:2956-2969
microRNA (miRNA) expression profiling of cancer versus normal cells may reveal the characteristic regulatory features that can be correlated to altered gene expression in both human and animal models of cancers. In this study, the comprehensive expre
Publikováno v:
Veterinary and Comparative Oncology. 13:322-336
Spatial/temporal controls of development are regulated by the homeotic (HOX) gene complex and require integration with oncogenes and tumour suppressors regulating cell cycle exit. Spontaneously derived neoplastic canine mammary carcinoma cell models