Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Patricia L. Brazee"'
Autor:
Laura A. Dada, Lynn C. Welch, Natalia D. Magnani, Ziyou Ren, Hyebin Han, Patricia L. Brazee, Diego Celli, Annette S. Flozak, Anthea Weng, Mariana Maciel Herrerias, Vitalii Kryvenko, István Vadász, Constance E. Runyan, Hiam Abdala-Valencia, Masahiko Shigemura, S. Marina Casalino-Matsuda, Alexander V. Misharin, G.R. Scott Budinger, Cara J. Gottardi, Jacob I. Sznajder
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with acute respiratory distress syndrome (A
Externí odkaz:
https://doaj.org/article/27f8a7d5d6534376bca1fe588efdba2a
Autor:
Rachel S. Knipe, Md Nurunnabi, Clemens K. Probst, Jillian J. Spinney, Elizabeth Abe, Rajendran J. C. Bose, Khanh Ha, Amanda Logue, Trong Nguyen, Rachel Servis, Matthew Drummond, Alexis Haring, Patricia L. Brazee, Benjamin D. Medoff, Jason R. McCarthy
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L190-L198
Pulmonary fibrosis is characterized by the accumulation of myofibroblasts in the lung and progressive tissue scarring. Fibroblasts exist across a spectrum of states, from quiescence in health to activated myofibroblasts in the setting of injury. High
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a075ae371aab587a25d994a2b018da1f
https://doi.org/10.1152/ajplung.00086.2022
https://doi.org/10.1152/ajplung.00086.2022
Autor:
Patricia L Brazee, Rachel S Knipe
Publikováno v:
American Journal of Respiratory and Critical Care Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d002f2b44b09a88f70ddad06c12dbb
https://doi.org/10.1164/rccm.202303-0382ed
https://doi.org/10.1164/rccm.202303-0382ed
Autor:
Patricia L. Brazee, Pritin N. Soni, Elmira Tokhtaeva, Natalia Magnani, Alex Yemelyanov, Harris R. Perlman, Karen M. Ridge, Jacob I. Sznajder, Olga Vagin, Laura A. Dada
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The alveolar epithelium secretes cytokines and chemokines that recruit immune cells to the lungs, which is essential for fighting infections but in excess can promote lung injury. Overexpression of FXYD5, a tissue-specific regulator of the Na,K-ATPas
Externí odkaz:
https://doaj.org/article/5a94a980c98f4cd2850a792e20e240b9
Autor:
Patricia L. Brazee, Jacob I. Sznajder
Publikováno v:
Archivos De Bronconeumologia
Archivos de Bronconeumología
Archivos de Bronconeumología (English Edition)
Archivos de Bronconeumología
Archivos de Bronconeumología (English Edition)
Influenza virus infection is characterized by symptoms ranging from mild congestion and body aches to severe pulmonary edema and respiratory failure. While the majority of those exposed have minor symptoms and recover with little morbidity, an estima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a640dc186048c5cc6e6ab1dab9c4fc
https://doi.org/10.1016/j.arbr.2020.04.008
https://doi.org/10.1016/j.arbr.2020.04.008
Autor:
Laura A. Dada, Lynn C. Welch, Natalia D. Magnani, Ziyou Ren, Patricia L. Brazee, Diego Celli, Annette S. Flozak, Anthea Weng, Mariana Maciel-Herrerias, Vitalii Kryvenko, István Vadász, Constance E Runyan, Hiam Abdala-Valencia, Masahiko Shigemura, S. Marina Casalino-Matsuda, Alexander V. Misharin, G.R. Scott Budinger, Cara J. Gottardi, Jacob I. Sznajder
Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are among the most common symptoms in patients with COVID-19 after hospital discharge. In mechanically ventilated patients with ARDS secondary to SARS-CoV-2 pneumonia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9f94ba5428f83a06139ea42bb83303
https://doi.org/10.1101/2022.01.12.475264
https://doi.org/10.1101/2022.01.12.475264
Autor:
Alicia Franklin, Katharine E. Black, Barry S. Shea, Patricia L. Brazee, Benjamin D. Medoff, Jason W. Griffith, Andreane Cartier, Francesca Giacona, Andrew Kuo, Elizabeth A Abe, Clemens K Probst, Rachel S. Knipe, Matt Drummond, Lida P. Hariri, Christina Christoffersen, Andrew M. Tager, Amanda Logue, Eric Engelbrecht, Sydney B. Montesi, Timothy Hla, Jillian J Spinney
Publikováno v:
Am J Respir Cell Mol Biol
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease which leads to significant morbidity and mortality from respiratory failure. The two drugs currently approved for clinical use slow the rate of decline in lung function but have no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67d11fc3fdced4d69fa7beeeb07c905
https://pubmed.ncbi.nlm.nih.gov/34343038
https://pubmed.ncbi.nlm.nih.gov/34343038
Autor:
G. R. Scott Budinger, Patricia L. Brazee, Luisa Morales-Nebreda, Natalia Magnani, Joe G.N. Garcia, Jacob I. Sznajder, Kazuhiro Iwai, Karen M. Ridge, Laura A. Dada, Alexander V. Misharin
Publikováno v:
J Clin Invest
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Influenza A virus (IAV) is among the most common causes of pneumonia-related death worldwide. Pulmonary epithelial cells are the primary target for viral infection and replication and respond by releasing inflammatory mediators that recruit immune ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9aa7b7c0420ce80f2571e73be48305
https://doi.org/10.1172/jci128368
https://doi.org/10.1172/jci128368
Autor:
Katharine E. Black, Norihiko Sakai, Jillian J Spinney, Linlin Zhang, James K. Liao, Andrew M. Tager, David Lagares, Alicia Franklin, Benjamin D. Medoff, Rachel S. Knipe, Paula Grasberger, Patricia L. Brazee, Barry S. Shea, Clemens K. Probst
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 58:471-481
Pulmonary fibrosis is thought to result from dysregulated wound repair after repetitive lung injury. Many cellular responses to injury involve rearrangements of the actin cytoskeleton mediated by the two isoforms of the Rho-associated coiled-coil-for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4d303cf64cbf0d2d2302e8cb238cfd
https://doi.org/10.1165/rcmb.2017-0075oc
https://doi.org/10.1165/rcmb.2017-0075oc
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 54:761-768
The covalent attachment of ubiquitin to target proteins is one of the most prevalent post-translational modifications, regulating a myriad of cellular processes including cell growth, survival, and metabolism. Recently, a novel RING E3 ligase complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb1224b9a4621149dd2d8abc64d8fd4
https://doi.org/10.1165/rcmb.2016-0014tr
https://doi.org/10.1165/rcmb.2016-0014tr