Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patricia, Pablos"'
Autor:
Aitziber Mendiguren, Jon Jatsu Azkue, Zigor Aira, María Carmen Medrano, Patricia Pablos, Joseba Pineda, Itsaso Buesa, María Teresa Santamarta
Publikováno v:
British Journal of Pharmacology. 174:2758-2772
Background and Purpose Regulation of μ receptor dynamics such as its trafficking is a possible mechanism underlying opioid tolerance that contributes to inefficient recycling of opioid responses. We aimed to characterize the functional turnover of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ed6ecbef6bacf5e04850e660ffe013d
https://doi.org/10.1111/bph.13901
https://doi.org/10.1111/bph.13901
Publikováno v:
Neuropharmacology. 99:422-431
Nitric oxide (NO) is involved in desensitization of μ-opioid receptors (MOR). We used extracellular recordings in vitro to unmask the NO-dependent pathways involved in MOR desensitization in the rat locus coeruleus (LC). Perfusion with ME (3 and 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e99c4fb1d4a5cbe900e9843d2778a93
https://doi.org/10.1016/j.neuropharm.2015.08.004
https://doi.org/10.1016/j.neuropharm.2015.08.004
Autor:
María Carmen, Medrano, María Teresa, Santamarta, Patricia, Pablos, Zigor, Aira, Itsaso, Buesa, Jon Jatsu, Azkue, Aitziber, Mendiguren, Joseba, Pineda
Publikováno v:
British journal of pharmacology. 174(16)
Regulation of μ receptor dynamics such as its trafficking is a possible mechanism underlying opioid tolerance that contributes to inefficient recycling of opioid responses. We aimed to characterize the functional turnover of μ receptors in the nora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7da5250362ce5dc5778d7208a640d993
https://pubmed.ncbi.nlm.nih.gov/28589556
https://pubmed.ncbi.nlm.nih.gov/28589556
Publikováno v:
Proceedings of MOL2NET, International Conference on Multidisciplinary Sciences.
Nitric oxide (NO) is involved in acute μ-opioid receptor (MOR) desensitization in the locus coeruleus (LC) and in the neuroadaptations following chronic morphine administration. However, the role of NO and NO-derived reactive oxygen species (ROS) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80686d19166feebdba8bd263d67a48c2
https://doi.org/10.3390/mol2net-1-b022
https://doi.org/10.3390/mol2net-1-b022