Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Patricia, Krief"'
Autor:
Laura Guerenne, Stéphanie Beurlet, Mohamed Said, Petra Gorombei, Carole Le Pogam, Fabien Guidez, Pierre de la Grange, Nader Omidvar, Valérie Vanneaux, Ken Mills, Ghulam J Mufti, Laure Sarda-Mantel, Maria Elena Noguera, Marika Pla, Pierre Fenaux, Rose Ann Padua, Christine Chomienne, Patricia Krief
Publikováno v:
Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-20 (2016)
Abstract Background In spite of the recent discovery of genetic mutations in most myelodysplasic (MDS) patients, the pathophysiology of these disorders still remains poorly understood, and only few in vivo models are available to help unravel the dis
Externí odkaz:
https://doaj.org/article/5f34a28afe924b7bb0e3dc96b14f7206
Autor:
Maria Elena Noguera, Satyananda Patel, Niclas Setterblad, Laure Sarda-Mantel, Saravanan Ganesan, Christine Chomienne, Pierre de la Grange, Petra Gorombei, Patricia Krief, Rose Ann Padua, Pascale Merlet, Laure Goursaud, R.R. West, Mathieu Chiquet, Christophe Leboeuf, Jacqueline Boultwood, Nader Omidvar, Nilgun Tekin, Marika Pla, Fabien Guidez, Stephanie Beurlet, Anne Janin, Carole Le Pogam, Michael Andreeff, Lionel Ades, Laura Guerenne, Andrea Pellagatti, Marina Konopleva, Pierre Fenaux
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10658, p 10658 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, 2021, 22 (19), pp.10658. ⟨10.3390/ijms221910658⟩
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, 2021, 22 (19), pp.10658. ⟨10.3390/ijms221910658⟩
During transformation, myelodysplastic syndromes (MDS) are characterized by reducing apoptosis of bone marrow (BM) precursors. Mouse models of high risk (HR)-MDS and acute myelogenous leukemia (AML) post-MDS using mutant NRAS and overexpression of hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e678a475b0e1f88e9e6ea9af51f9cb
https://www.mdpi.com/1422-0067/22/19/10658
https://www.mdpi.com/1422-0067/22/19/10658
Autor:
Marika Pla, B. Hosten, F. Hontonnou, Patricia Krief, C. San, Rose Ann Padua, N. Vignal, L. Sarda-Mantel, P. Fenaux, C. Chomienne
Publikováno v:
HemaSphere. 3:606-607
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c577c135444a27c4bee53a02d6bfc3
https://doi.org/10.1097/01.hs9.0000563596.17845.ee
https://doi.org/10.1097/01.hs9.0000563596.17845.ee
Autor:
Marika Pla, Pierre Fenaux, Marie-Hélène Schlageter, Nader Omidvar, Satyananda Patel, Petra Gorombei, Martine Chopin, Carole Le Pogam, Elena Bernasconi, Vikram Mathews, Maria-Elena Noguera, Patricia Krief, Flore Sicre, Laura Guerenne, Nilgun Tekin, Robert West, Christine Chomienne, Ansu Abu, Rose Ann Padua
Publikováno v:
Oncotarget
We have previously shown that a specific promyelocytic leukemia-retinoic acid receptor alpha (PML-RARA) DNA vaccine combined with all-trans retinoic acid (ATRA) increases the number of long term survivors with enhanced immune responses in a mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a71996b820f0b0af4e3b2832109a3ef
https://doi.org/10.18632/oncotarget.5572
https://doi.org/10.18632/oncotarget.5572
Autor:
Arnaud Sansonetti, Bruno Cassinat, Jean-Jacques Kiladjian, Rose Ann Padua, Alexandra Briend-Marchal, Patricia Krief, Christine Chomienne, Stephanie Beurlet
Publikováno v:
Experimental Hematology. 39:542-545
Objective Primary polycythemia in dogs is classified as a myeloproliferative syndrome with a chronic progressive course and unspecific symptoms. Diagnosis is based on exclusion criteria. In humans, the presence of an acquired recurrent mutation withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416a4784a040d29242b2a013cc1e48da
https://doi.org/10.1016/j.exphem.2011.02.003
https://doi.org/10.1016/j.exphem.2011.02.003
Autor:
Rose Ann Padua, Marina Konopleva, Fortune Hontonnou, Stéphane Giraudier, Mathieu Chiquet, Bruno Cassinat, Christine Chomienne, Lionel Adès, Benoit Hosten, Panhong Gou, Nicolas Vignal, Patricia Krief, Pierre Fenaux, Fabien Zassadowski, Niclas Setterblad, Laure Sarda-Mantel, Marika Pla, Michael Andreeff, Claire Kappel
Publikováno v:
Blood. 132:5497-5497
Introduction: Targeted drugs are needed for HR-MDS/AML, particularly in elderly patients and Venetoclax, approved for some CLL, gives promising results in elderly AML. Assays to predict response to treatment may enable us to deliver personalized trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7aa3cb59d61cf8184be610222a38b51
https://doi.org/10.1182/blood-2018-99-114212
https://doi.org/10.1182/blood-2018-99-114212
Autor:
Laura Guerenne, Ansu Abu Alex, Vikram Mathews, Christine Chomienne, Patricia Krief, R.R. West, Rose Ann Padua, Pierre Fenaux, Satyananda Patel, Nader Omidvar, Marika Pla, Marie-Hélène Schlageter, Petra Gorombei, Lionel Adès, Saravanan Ganesan
Publikováno v:
Blood Cancer Journal
pVAX14DNA-mediated add-on immunotherapy combined with arsenic trioxide and all- trans retinoic acid targeted therapy effectively increases the survival of acute promyelocytic leukemia mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f08ec93bf3064946a8300c21f00d3ad
https://pubmed.ncbi.nlm.nih.gov/26657197
https://pubmed.ncbi.nlm.nih.gov/26657197
Autor:
Joëlle Morin, Véronique Laloux, D. Dubois-Laforgue, Jean-Claude Carel, Patricia Krief, Philippe Halbout, Christian Boitard, Agnès Lehuen, Sylviane Muller, Jacques Jami, Karine Vallon-Geoffroy, Jean-Paul Briand, Karine Thébault-Baumont
Publikováno v:
Journal of Clinical Investigation. 111:851-857
Accumulating evidence favors a role for proinsulin as a key autoantigen in diabetes. In the mouse, two proinsulin isoforms coexist. Most studies point to proinsulin 2 as the major isoform recognized by T cells in the NOD mouse. We studied mice in whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd41737046fffa05d229d9363a36ecf7
https://doi.org/10.1172/jci16584
https://doi.org/10.1172/jci16584
Autor:
Danièle Dubois-Lafforgue, Jacques Jami, Laurent Mogenet, Christian Boitard, Patricia Krief, Karine Thébault
Publikováno v:
Diabetes. 51:S489-S493
Insulin is a major disease determinant in type 1 diabetes, type 2 diabetes, and related disorders. The role of variations in the expression of the insulin gene has been proposed in genetic susceptibility to the three pathological conditions in humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f051096df232f8bc50727ebf97ea635
https://doi.org/10.2337/diabetes.51.2007.s489
https://doi.org/10.2337/diabetes.51.2007.s489
Publikováno v:
Journal of Child Neurology. 23:582-584
Despite the high incidence of epilepsy in very young children, the availability of approved antiepileptic drugs for this population is limited. This study assessed the efficacy and tolerability of levetiracetam in children younger than 2 years of age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423d933a9a23422298e73eb42c3dfc02
https://doi.org/10.1177/0883073807309781
https://doi.org/10.1177/0883073807309781