Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Patricia, Karjian"'
Autor:
Karen Lundgren, Roy Grecko, Srinivas Rao Kasibhatla, Kevin Hong, Adeela Kamal, Rachel Lough, Gregg Timony, Lawrence C. Fritz, Edgar H. Ulm, Marco A. Biamonte, Patricia Karjian, David J. Busch, Marcus F. Boehm, Robert K. Mansfield, Francis Burrows, John Brekken, Yingqing Ran, John Sensintaffar
Publikováno v:
Journal of Medicinal Chemistry. 50:2767-2778
Heat shock protein 90 (Hsp90) is a molecular chaperone protein implicated in stabilizing the conformation and maintaining the function of many cell-signaling proteins. Many oncogenic proteins are more dependent on Hsp90 in maintaining their conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::256512d0ba0657d93f9e55a9f6d48e83
https://doi.org/10.1021/jm050752+
https://doi.org/10.1021/jm050752+
Autor:
Junhua Fan, Daun Chung, Diana Choi, Lin Zhang, Patricia Karjian, Marcus F. Boehm, Roy Grecko, Yong-Ching Yang, Francis Burrows, Gregg Timony, Hong Zhang
Publikováno v:
International Journal of Cancer. 120:918-926
The geldanamycin derivative 17-allyamino-17-demethoxygeldanamycin (17-AAG) is a clinical stage ATP-competitive HSP90 inhibitor that induces degradation of HSP90 client proteins. 17-AAG contains 1 ansamycin moiety and is highly potent in conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac7a2945c6f1ad0548bbb769f124c1b
https://doi.org/10.1002/ijc.22392
https://doi.org/10.1002/ijc.22392
Autor:
Hong, Zhang, Yong-Ching, Yang, Lin, Zhang, Junhua, Fan, Daun, Chung, Diana, Choi, Roy, Grecko, Gregg, Timony, Patricia, Karjian, Marcus, Boehm, Francis, Burrows
Publikováno v:
International journal of cancer. 120(4)
The geldanamycin derivative 17-allyamino-17-demethoxygeldanamycin (17-AAG) is a clinical stage ATP-competitive HSP90 inhibitor that induces degradation of HSP90 client proteins. 17-AAG contains 1 ansamycin moiety and is highly potent in conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75e0d8234eb94cdde89013c9aa6f8333
https://pubmed.ncbi.nlm.nih.gov/17131314
https://pubmed.ncbi.nlm.nih.gov/17131314