Zobrazeno 1 - 10
of 480
pro vyhledávání: '"Patrice VIENS"'
Autor:
François Bertucci, Florence Lerebours, Michele Ceccarelli, Arnaud Guille, Najeeb Syed, Pascal Finetti, José Adélaïde, Steven Van Laere, Anthony Goncalves, Patrice Viens, Daniel Birnbaum, Emilie Mamessier, Céline Callens, Davide Bedognetti
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Inflammatory breast cancer (IBC) is the most pro-metastatic form of BC. Better understanding of its enigmatic pathophysiology is crucial. We report here the largest whole-exome sequencing (WES) study of clinical IBC samples. Metho
Externí odkaz:
https://doaj.org/article/d411209f682649f3b4011eb089a7cbba
Autor:
Charlotte Rypens, François Bertucci, Pascal Finetti, Fredika Robertson, Sandra V. Fernandez, Naoto Ueno, Wendy A. Woodward, Kenneth Van Golen, Peter Vermeulen, Luc Dirix, Patrice Viens, Daniel Birnbaum, Gayathri R. Devi, Massimo Cristofanilli, Steven Van Laere
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Inflammatory breast cancer (IBC) is an aggressive disease for which the spectrum of preclinical models was rather limited in the past. More recently, novel cell lines and xenografts have been developed. This study evaluates the transcriptome
Externí odkaz:
https://doaj.org/article/5f7d6093dd1c479cb755cd0da5f6d23f
Autor:
François Bertucci, Anthony Gonçalves, Arnaud Guille, José Adelaïde, Séverine Garnier, Nadine Carbuccia, Emilien Billon, Pascal Finetti, Patrick Sfumato, Audrey Monneur, Christophe Pécheux, Martin Khran, Serge Brunelle, Lenaïg Mescam, Jeanne Thomassin-Piana, Flora Poizat, Emmanuelle Charafe-Jauffret, Olivier Turrini, Eric Lambaudie, Magali Provansal, Jean-Marc Extra, Anne Madroszyk, Marine Gilabert, Renaud Sabatier, Cécile Vicier, Emilie Mamessier, Christian Chabannon, Jihane Pakradouni, Patrice Viens, Fabrice André, Gwenaelle Gravis, Cornel Popovici, Daniel Birnbaum, Max Chaffanet
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background The benefit of precision medicine based on relatively limited gene sets and often-archived samples remains unproven. PERMED-01 (NCT02342158) was a prospective monocentric clinical trial assessing, in adults with advanced solid can
Externí odkaz:
https://doaj.org/article/685cee8dc4e4477fb464978bcebb91ff
Autor:
François Bertucci, Charlotte Rypens, Pascal Finetti, Arnaud Guille, José Adélaïde, Audrey Monneur, Nadine Carbuccia, Séverine Garnier, Piet Dirix, Anthony Gonçalves, Peter Vermeulen, Bisrat G. Debeb, Xiaoping Wang, Luc Dirix, Naoto T. Ueno, Patrice Viens, Massimo Cristofanilli, Max Chaffanet, Daniel Birnbaum, Steven Van Laere
Publikováno v:
Molecular Oncology, Vol 14, Iss 3, Pp 504-519 (2020)
Inflammatory breast cancer (IBC) is the most pro‐metastatic form of breast cancer. Better understanding of its pathophysiology and identification of actionable genetic alterations (AGAs) are crucial to improve systemic treatment. We aimed to define
Externí odkaz:
https://doaj.org/article/4432b063855f42719a19cc390e05d2c5
Autor:
Didier Blaise, Pierre Berger, Djamel Mokart, Jacques Camerlo, Emmanuelle Fougereau, Marc Giovannini, Gilles Houvenaeghel, Olivier Turrini, Christian Chabannon, Gilles Piana, Isabelle Brenot-Rossi, Agnès Tallet, Anthony Gonçalves, Aude Charbonnier, Norbert Vey, Sabrina Grossi, Patrice Viens
Publikováno v:
Clinical Hematology International, Vol 3, Iss 4 (2021)
During the COVID-19 pandemic, it was rapidly established that cancer patients have an increased risk of developing severe forms of the 2019 coronavirus disease (COVID-19) due to a backlog of cancer diagnostics and immunosuppressive treatments. Cancer
Externí odkaz:
https://doaj.org/article/cfb97d61df21416196b03400bab47992
Autor:
François Bertucci, Laurys Boudin, Pascal Finetti, Christophe Van Berckelaer, Peter Van Dam, Luc Dirix, Patrice Viens, Anthony Gonçalves, Naoto T. Ueno, Steven Van Laere, Daniel Birnbaum, Emilie Mamessier
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Background. Anti-PD1/PDL1 immune checkpoint inhibitors (ICIs) showed promising results in breast cancer, and exploration of additional actionable immune checkpoints is ongoing. Inflammatory breast cancer (IBC) is an aggressive form of disease, the im
Externí odkaz:
https://doaj.org/article/d7404edd768848c586b961c9707f2e37
Publikováno v:
Case Reports in Oncology, Vol 7, Iss 1, Pp 33-38 (2014)
Background: Nervous central system metastases from head and neck squamous cell carcinoma (SCC) are rare. We report an exceptional case of isolated leptomeningeal and spinal cord involvement few years after the diagnosis of invasive SCC of the lip. Ca
Externí odkaz:
https://doaj.org/article/2ad97975725f42f3bee5aeb0b24beb6e
Autor:
Anne-Catherine Lhoumeau, Sébastien Martinez, Jean-Marie Boher, Geneviève Monges, Rémy Castellano, Armelle Goubard, Marie Doremus, Flora Poizat, Bernard Lelong, Cécile de Chaisemartin, Florence Bardin, Patrice Viens, Jean-Luc Raoul, Thomas Prebet, Michel Aurrand-Lions, Jean-Paul Borg, Anthony Gonçalves
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0123768 (2015)
Biomarkers and novel therapeutic targets are urgently needed in colorectal cancer (CRC). The pseudo tyrosine kinase receptor 7 (PTK7) is involved in planar cell polarity and it is deregulated in various malignancies, including CRC. Yet, little is kno
Externí odkaz:
https://doaj.org/article/7983a2c4d68549deb5ce63311ec7ee69
Autor:
Stéphanie Cornen, Arnaud Guille, José Adélaïde, Lynda Addou-Klouche, Pascal Finetti, Marie-Rose Saade, Marwa Manai, Nadine Carbuccia, Ismahane Bekhouche, Anne Letessier, Stéphane Raynaud, Emmanuelle Charafe-Jauffret, Jocelyne Jacquemier, Salvatore Spicuglia, Hugues de The, Patrice Viens, François Bertucci, Daniel Birnbaum, Max Chaffanet
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e81843 (2014)
Breast cancers (BCs) of the luminal B subtype are estrogen receptor-positive (ER+), highly proliferative, resistant to standard therapies and have a poor prognosis. To better understand this subtype we compared DNA copy number aberrations (CNAs), DNA
Externí odkaz:
https://doaj.org/article/dd7de6bb6d7f4633bb855660fd9edec5
Autor:
Laetitia Huiart, Anne-Deborah Bouhnik, Dominique Rey, Frédérique Rousseau, Frédérique Retornaz, Mégane Meresse, Marc Karim Bendiane, Patrice Viens, Roch Giorgi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81677 (2013)
PurposeAromatase inhibitor therapy (AI) significantly improves survival in breast cancer patients. Little is known about adherence and persistence to aromatase inhibitors and about the causes of treatment discontinuation among older women.MethodsWe c
Externí odkaz:
https://doaj.org/article/2c71efe80a1549d897d65ea0150e55b3