Výsledky vyhledávání - "Patrice R. Rioux"

Selective killing of cancer cells based on loss of heterozygosity and normal variation in the human genome: a new paradigm for anticancer drug therapy

Autor: Andrea R. Schievella, Vincent P. Stanton, Jeffrey Olson, Erica Burns, Patrice R. Rioux, Brett P. Monia, David E. Housman, Kristina M. Lemonidis, James P. Basilion

Publikováno v: Molecular pharmacology. 56(2)

Most drugs for cancer therapy are targeted to relative differences in the biological characteristics of cancer cells and normal cells. The therapeutic index of such drugs is theoretically limited by the magnitude of such differences, and most antican

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e99684406d94d7b30c2d6dd5594add8
https://pubmed.ncbi.nlm.nih.gov/10419555

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