Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Patrice Quintana"'
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Akademický článek
Altered action potential waveform and shorter axonal initial segment in hiPSC-derived motor neurons with mutations in VRK1
Autor: Rémi Bos, Khalil Rihan, Patrice Quintana, Lara El-Bazzal, Nathalie Bernard-Marissal, Nathalie Da Silva, Rosette Jabbour, André Mégarbané, Marc Bartoli, Frédéric Brocard, Valérie Delague
Publikováno v: Neurobiology of Disease, Vol 164, Iss , Pp 105609- (2022)
We recently described new pathogenic variants in VRK1, in patients affected with distal Hereditary Motor Neuropathy associated with upper motor neurons signs. Specifically, we provided evidences that hiPSC-derived Motor Neurons (hiPSC-MN) from these
Externí odkaz: https://doaj.org/article/e0889f703ae042e3a01c7a9e37be8b23
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2
Akademický článek
Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells.
Autor: Marie Deck, Gerben Van Hameren, Graham Campbell, Nathalie Bernard-Marissal, Jérôme Devaux, Jade Berthelot, Alise Lattard, Jean-Jacques Médard, Benoît Gautier, Sophie Guelfi, Scarlette Abbou, Patrice Quintana, Juan Manuel Chao de la Barca, Pascal Reynier, Guy Lenaers, Roman Chrast, Nicolas Tricaud
Publikováno v: PLoS ONE, Vol 17, Iss 10, p e0272097 (2022)
While lactate shuttle theory states that glial cells metabolize glucose into lactate to shuttle it to neurons, how glial cells support axonal metabolism and function remains unclear. Lactate production is a common occurrence following anaerobic glyco
Externí odkaz: https://doaj.org/article/a7a329704faf4d219f8244ef73cf9d20
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3
Akademický článek
In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathies
Autor: Gerben van Hameren, Graham Campbell, Marie Deck, Jade Berthelot, Benoit Gautier, Patrice Quintana, Roman Chrast, Nicolas Tricaud
Publikováno v: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Mitochondria are critical for the function and maintenance of myelinated axons notably through Adenosine triphosphate (ATP) production. A direct by-product of this ATP production is reactive oxygen species (ROS), which are highly deleterious
Externí odkaz: https://doaj.org/article/095995978f2f48ecbb33858c5b4b00bb
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4
Imbalance of NRG1-ERBB2/3 signalling underlies altered myelination in Charcot–Marie–Tooth disease 4H
Autor: Lara, El-Bazzal, Adeline, Ghata, Clothilde, Estève, Jihane, Gadacha, Patrice, Quintana, Christel, Castro, Nathalie, Roeckel-Trévisiol, Frédérique, Lembo, Nicolas, Lenfant, André, Mégarbané, Jean-Paul, Borg, Nicolas, Lévy, Marc, Bartoli, Yannick, Poitelon, Pierre L, Roubertoux, Valérie, Delague, Nathalie, Bernard-Marissal
Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, 2022, ⟨10.1093/brain/awac402⟩
International audience; Charcot Marie Tooth disease is one of the most common inherited neurological disorders, affecting either axons from the motor and/or sensory neurons or Schwann cells of the peripheral nervous system, and caused by more than 10
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0782ce2aa538c788166fadb0e6d00695
https://amu.hal.science/hal-03977684
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7
Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons
Autor: Patrice, Quintana, David, Soto, Olivier, Poirot, Marzieh, Zonouzi, Stephan, Kellenberger, Dominique, Muller, Roman, Chrast, Stuart G, Cull-Candy
Publikováno v: The Journal of Physiology
Journal of Physiology, vol. 593, no. 19, pp. 4373-4386
KEY POINTS: The hippocampal CA1 region is highly vulnerable to ischaemic stroke. Two forms of AMPA receptor (AMPAR) plasticity an anoxic form of long term potentiation and a delayed increase in Ca(2+) permeable (CP) AMPARs contribute to this suscepti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b898bc4493d62c070333a0de93ea33ab
https://serval.unil.ch/notice/serval:BIB_404FF4460E4F
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8
Neurite growth acceleration of adult Dorsal Root Ganglion neurons illuminated by low-level Light Emitting Diode light at 645 nm
Autor: Fabrice Bardin, Hassan Boukhaddaoui, Michel Chammas, Jefferson Braga Silva, Benoit Charlot, Patrice Quintana, Lucie Diouloufet, Lambert Paris, Victor Sieso, Jean-Michel Bec, Marion Burland, Jean Valmier, Chamroeun Sar
Publikováno v: Journal of Biophotonics
Journal of Biophotonics, Wiley, 2015, 8 (6), pp.480-488. ⟨10.1002/jbio.201400052⟩
The effect of a 645 nm Light Emitting Diode (LED) light irradiation on the neurite growth velocity of adult Dorsal Root Ganglion (DRG) neurons with peripheral axon injury 4-10 days before plating and without previous injury was investigated. The real
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042ae1ad3eaa2732d7ec7f93f809d764
https://hal.archives-ouvertes.fr/hal-01398771
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9
Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures
Autor: Patrice Quintana, Stefano Alberi, David Hakkoum, Dominique Muller
Publikováno v: European Journal of Neuroscience, Vol. 23, No 4 (2006) pp. 975-983
Transient anoxia/hypoglycaemia in organotypic hippocampal slice cultures, a model of transient brain ischaemia, ultimately results in delayed cell death. Although the mechanisms underlying this delayed death remain unknown, an increase in excitatory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e06e23d52ba45dd0948df19db6fc8d
https://pubmed.ncbi.nlm.nih.gov/16519662
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