Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Patrice Newton"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Autophagy is a fundamental and highly conserved eukaryotic process, responsible for maintaining cellular homeostasis and releasing nutrients during times of starvation. An increasingly important function of autophagy is its role in the cell autonomou
Externí odkaz:
https://doaj.org/article/e56af28c13f64520b692bc51c0e9fb7b
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006101 (2016)
Coxiella burnetii is an intracellular bacterial pathogen that infects alveolar macrophages and replicates within a unique lysosome-derived vacuole. When Coxiella is trafficked to a host cell lysosome the essential Dot/Icm type IV secretion system is
Externí odkaz:
https://doaj.org/article/8daffb6168754edd9c93a027facb349a
Autor:
Kaylene J. Simpson, Patrice Newton, Hayley J. Newton, Piyush B. Madhamshettiwar, Shawna C. O. Reed, Nicole Lau, Laura E. Edgington-Mitchell, Craig R. Roy, Sze Ying Ong, Bangyan Xu, Shivani Pasricha, David R. Thomas
Publikováno v:
Proceedings of the National Academy of Sciences. 117:6801-6810
Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-like vacuole through activation of a Dot/Icm-type IVB secretion system and subsequent translocation of effectors that remodel the host cell. Here a genome-wide small interfe
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Autophagy is a fundamental and highly conserved eukaryotic process, responsible for maintaining cellular homeostasis and releasing nutrients during times of starvation. An increasingly important function of autophagy is its role in the cell autonomou
Autor:
Patrice, Newton, David R, Thomas, Shawna C O, Reed, Nicole, Lau, Bangyan, Xu, Sze Ying, Ong, Shivani, Pasricha, Piyush B, Madhamshettiwar, Laura E, Edgington-Mitchell, Kaylene J, Simpson, Craig R, Roy, Hayley J, Newton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Coxiella burnetii is a unique bacterial pathogen that replicates to high numbers in a lysosome-like intracellular niche. This study identified host proteins that contribute to the pathogen’s capacity to establish this niche and activat
Autor:
Chen Ai Khoo, Hayley J. Newton, Patrice Newton, Bhavna Padmanabhan, Laura F. Fielden, Abderrahman Hachani, Nichollas E. Scott, Diana Stojanovski, Hyun-Jung Cho, Craig R. Roy, David R. Thomas
Publikováno v:
Infection and Immunity. 88
Coxiella burnetii is an obligate intracellular bacterial pathogen that replicates inside the lysosome-derived Coxiella-containing vacuole (CCV). To establish this unique niche, C. burnetii requires the Dot/Icm type IV secretion system (T4SS) to trans
Autor:
Hayley J. Newton, Dedreia Tull, Malcolm J. McConville, Patrice Newton, Yi Wei Lee, David P De Souza, Nitika Neha, Miku Kuba, Abderrahman Hachani, Saravanan Dayalan, Vicki Bennett-Wood, Fiona M. Sansom, Brunda Nijagal
Publikováno v:
Infect Immun
The zoonotic bacterial pathogen Coxiella burnetii is the causative agent of Q fever, a febrile illness which can cause a serious chronic infection. C. burnetii is a unique intracellular bacterium which replicates within host lysosome-derived vacuoles
Autor:
Bhavna, Padmanabhan, Laura F, Fielden, Abderrahman, Hachani, Patrice, Newton, David R, Thomas, Hyun-Jung, Cho, Chen Ai, Khoo, Diana, Stojanovski, Craig R, Roy, Nichollas E, Scott, Hayley J, Newton
Publikováno v:
Infect Immun
Coxiella burnetii is an obligate intracellular bacterial pathogen that replicates inside the lysosome-derived Coxiella-containing vacuole (CCV). To establish this unique niche, C. burnetii requires the Dot/Icm type IV secretion system (T4SS) to trans
Publikováno v:
Defense Against Biological Attacks ISBN: 9783030030704
The intracellular bacterial pathogen Coxiella burnetii causes the zoonotic disease Q fever. Due to the combined traits of a very low infectious dose, significant environmental resistance, and the debilitating consequences of infection, this pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::903845aab8fae576405387b55ac58486
https://doi.org/10.1007/978-3-030-03071-1_9
https://doi.org/10.1007/978-3-030-03071-1_9
Autor:
Christa E. Müller, Wenjin Li, Sang Yong Lee, Patrice Newton, Enas M. Malik, Younis Baqi, Amelie Fiene, Elizabeth L. Hartland
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:4363-4371
Legionella pneumophila is an aerobic, Gram-negative bacterium of the genus Legionella, which constitutes the major causative agent of Legionnaires' disease. Recently a nucleoside triphosphate diphosphohydrolase (NTPDase) from L. pneumophila was ident