Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Patrice M. Witschen"'
Autor:
Emily A. Jesser, Nicholas J. Brady, Danielle N. Huggins, Patrice M. Witschen, Christine H. O’Connor, Kathryn L. Schwertfeger
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background In breast cancer, complex interactions between tumor cells and cells within the surrounding stroma, such as macrophages, are critical for tumor growth, progression, and therapeutic response. Recent studies have highlighted the com
Externí odkaz:
https://doaj.org/article/ebd5cadb39fe444bbd34bca1f5663296
Autor:
Ying Wang, Thomas S Chaffee, Rebecca S LaRue, Danielle N Huggins, Patrice M Witschen, Ayman M Ibrahim, Andrew C Nelson, Heather L Machado, Kathryn L Schwertfeger
Publikováno v:
eLife, Vol 9 (2020)
Tissue-resident macrophages in the mammary gland are found in close association with epithelial structures and within the adipose stroma, and are important for mammary gland development and tissue homeostasis. Macrophages have been linked to ductal d
Externí odkaz:
https://doaj.org/article/b6cd20f4110c43bd9da5cbeb9507aef0
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 28
The extracellular matrix (ECM) is biochemically and biomechanically important for the structure and function of the mammary gland, which undergoes vast structural changes throughout pubertal and reproductive development. Although hyaluronan (HA) is a
Autor:
Patrice M. Witschen, Jaclyn A. Dykstra, Jennifer L. Granick, Laura O. Motschenbacher, Davis M. Seelig, Leslie C. Sharkey, Tim W. Carlson
Publikováno v:
Veterinary Clinical Pathology. 49:137-142
Lymphoma is a common hematopoietic neoplasm of dogs. A definitive diagnosis typically requires the collection of samples via fine-needle aspirate or biopsy. A unique case of canine renal T-cell lymphoma diagnosed using urine sediment microscopy with
Autor:
Kathryn L. Schwertfeger, Christine H. O’Connor, Emily A. Jesser, Patrice M. Witschen, Danielle N. Huggins, Nicholas J. Brady
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
BackgroundIn breast cancer, complex interactions between tumor cells and cells within the surrounding stroma, such as macrophages, are critical for tumor growth, progression, and therapeutic response. Recent studies have highlighted the complex natur
Autor:
Nicholas J. Brady, Lyubov Tiegs, Patrice M. Witschen, Danielle N. Huggins, Sarah A. Munro, Thomas S. Chaffee, Todd P. Knutson, James B. McCarthy, Rebecca S. LaRue, Kathryn L. Schwertfeger, Andrew C. Nelson
Publikováno v:
Cancers, Vol 12, Iss 2736, p 2736 (2020)
The authors wish to make the following corrections to this paper [...]
Autor:
Thomas S. Chaffee, James B. McCarthy, Kathryn L. Schwertfeger, Lyubov Tiegs, Todd P. Knutson, Nicholas J. Brady, Rebecca S. LaRue, Danielle N. Huggins, Sarah A. Munro, Patrice M. Witschen, Andrew C. Nelson
Publikováno v:
Cancers
Volume 12
Issue 5
Cancers, Vol 12, Iss 1325, p 1325 (2020)
Volume 12
Issue 5
Cancers, Vol 12, Iss 1325, p 1325 (2020)
Cancer has been conceptualized as a chronic wound with a predominance of tumor promoting inflammation. Given the accumulating evidence that the microenvironment supports tumor growth, we investigated hyaluronan (HA)-CD44 interactions within breast ca
Autor:
James B. McCarthy, Rebecca S. LaRue, Nicholas J. Brady, Kathryn L. Schwertfeger, Todd P. Knutson, Patrice M. Witschen, Andrew C. Nelson, Thomas S. Chaffee, Sarah A. Munro, Lyubov Tiegs
Publikováno v:
Cancer Research. 81:PO041-PO041
Hyaluronan (HA) is a large, soluble, glycosaminoglycan of the extracellular matrix that has anti-inflammatory effects under physiologic conditions. However, HA is cleaved into low molecular weight (LMW) fragments under conditions of cellular or organ
Autor:
Bruce Walcheck, Nicholas J. Brady, Laura R. Bohrer, Patrice M. Witschen, Pavlina Chuntova, Sarah E. Kemp, Thomas S. Chaffee, Kathryn L. Schwertfeger, Andrew C. Nelson
Publikováno v:
Genes & Cancer
The presence of inflammatory cells within the tumor microenvironment has been tightly linked to mammary tumor formation and progression. Specifically, interactions between tumor cells and infiltrating macrophages can contribute to the generation of a