Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Patrice Hugo"'
Publikováno v:
Journal of Proteome Research. 7:234-244
Proteomic discovery platforms generate both peptide expression information and protein identification information. Peptide expression data are used to determine which peptides are differentially expressed between study cohorts, and then these peptide
Autor:
Katherine Bonter, Eustache Paramithiotis, Heather Butler, Paul Kearney, Joanna M. Hunter, Patrice Hugo, Kossi Lekpor, Daniel Chelsky, Gregory J. Opiteck, Marie-Josée Benoit, Daniela Vasilescu, Michael Schirm
Publikováno v:
PROTEOMICS – Clinical Applications. 1:457-466
Multidimensional fingerprinting (MDF) utilizes measurable peptide characteristics to identify proteins. In this study, 3-D fingerprinting, namely, parent protein molecular weight, peptide mass, and peptide retention time on RPLC, is used to identify
Publikováno v:
Toxicology and Applied Pharmacology
Interaction of a single dose (36 mg/kg body wt) of the organochlorine pesticide dieldrin with mouse peritoneal macrophages was examined in C57Bl/6, (C57Bl/6 X A/J)F1, and A/J strains of different genetic resistance to mouse hepatitis virus 3 (MHV3) i
Autor:
Diane Gosselin, Danièle Gagné, Robert Hemmings, Patrice Hugo, Michèle Rivard, David L. Olive, Julie Poliquin-Fleury
Publikováno v:
Fertility and Sterility. 81:1513-1521
Objective To investigate the association between several factors such as demographics, personal habits, reproductive factors, menstrual characteristics, contraception, and clinical profile and the probability of having endometriosis. Setting Ten clin
Publikováno v:
Molecular Human Reproduction. 9:671-679
A major challenge in the comprehension of the endometrial transformations leading to the completion of each menstrual cycle in humans is in the identification of specific molecular pathways underlying these monthly turnovers. Towards this goal we com
Autor:
Kamran Shazand, Manon Lépine, Diane Gosselin, Patrice Hugo, Michèle Rivard, Christele Platon, Martin Pagé, Danièle Gagné
Publikováno v:
Fertility and Sterility. 80:876-885
Objective To determine whether the proportion of several leukocyte subsets is modulated in the endometrium of patients with endometriosis and, if yes, whether it can be used for diagnostic purposes. Design: Case-control study. Setting: Eight clinical
Autor:
Walid Mourad, Sophie Roy, Ann-Muriel Steff, Louis-François Bélanger, Michel J. Tremblay, Barbara K. Brott, Jean Charron, Patrice Hugo, Raymond L. Erikson
Publikováno v:
Molecular and Cellular Biology. 23:4778-4787
MEK is a dual-specificity kinase that activates the extracellular signal-regulated kinase (ERK) mitogen-activated protein (MAP) kinase upon agonist binding to receptors. The ERK/MAP kinase cascade is involved in cell fate determination in many organi
Autor:
Ann-Muriel Steff, Sylvie Lesage, Fabianne Philippoussis, Chantal Arguin, Marylène Fortin, Patrice Hugo, Pauline Johnson
Publikováno v:
Critical Reviews in Immunology. 23:421-440
The protein tyrosine phosphatase CD45 is a highly expressed glycoprotein present on all nucleated cells of hematopoietic origin. To date, all the functions attributed to CD45 are inherently coupled to its phosphatase activity. For instance, the regul
Publikováno v:
Biochemical Pharmacology
Dieldrin (36 mg/kg body weight) administered intraperitoneally prolonged recovery from infection with mouse hepatitis virus 3 (MHV3) in the genetically-resistant A/J strain, affected the humoral anti-MHV3 IgG immune response, and inhibited the intrin
Publikováno v:
The Journal of Immunology. 166:5044-5050
In early CD4(-)CD8(-) pro-thymocytes, signaling through the pre-TCR is crucial for survival and differentiation into CD4(+)CD8(+) cells. At this more mature stage, interactions between alphabetaTCR and self-Ag/MHC complexes in turn lead either to cel