Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Patrice Gouet"'
Publikováno v:
Pathogens, Vol 13, Iss 3, p 241 (2024)
Human T-cell Leukemia Virus type 1 (HTLV-1) is a human retrovirus responsible for leukaemia in 5 to 10% of infected individuals. Among the viral proteins, Tax has been described as directly involved in virus-induced leukemogenesis. Tax is therefore a
Externí odkaz:
https://doaj.org/article/25531c7ec53347c1b04111b51747c56a
Autor:
Nilanshu Manocha, Daphné Laubreton, Xavier Robert, Jacqueline Marvel, Virginie Gueguen-Chaignon, Patrice Gouet, Prashant Kumar, Madhu Khanna
Publikováno v:
Vaccines, Vol 12, Iss 3, p 316 (2024)
Dengue virus (DENV) infection continues to be a public health challenge, lacking a specific cure. Vaccination remains the primary strategy against dengue; however, existing live-attenuated vaccines display variable efficacy across four serotypes, inf
Externí odkaz:
https://doaj.org/article/9ea3161905ed48c4890a8d143a0651a8
Publikováno v:
Viruses, Vol 14, Iss 7, p 1397 (2022)
Retroviral integrase is a multimeric enzyme that catalyzes the integration of reverse-transcribed viral DNA into the cellular genome. Beyond integration, the Human immunodeficiency virus type 1 (HIV-1) integrase is also involved in many other steps o
Externí odkaz:
https://doaj.org/article/7262b0a0d8b346858da3442869c8a1ff
Autor:
Caroline Bayart, Angélique Mularoni, Nada Hemmani, Soumeya Kerachni, Joachim Jose, Patrice Gouet, Joseph Paladino, Marc Le Borgne
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 756 (2022)
Tetanus toxoid (TTd) plays an important role in the pharmaceutical world, especially in vaccines. The toxoid is obtained after formaldehyde treatment of the tetanus toxin. In parallel, current emphasis in the drug discovery field is put on producing
Externí odkaz:
https://doaj.org/article/c8ce40a7c2764f25ba9b96a34119e600
Autor:
Xavier Robert, Josiane Kassis-Sahyoun, Nicoletta Ceres, Juliette Martin, Michael R. Sawaya, Randy J. Read, Patrice Gouet, Pierre Falson, Vincent Chaptal
Publikováno v:
Data in Brief, Vol 19, Iss , Pp 753-757 (2018)
This data article makes available the informed computation of the whole Protein Data Bank (PDB) to investigate diffraction anisotropy on a large scale and to perform statistics. This data has been investigated in detail in “X-ray diffraction reveal
Externí odkaz:
https://doaj.org/article/f4bd863676414b1b8c77f34d47cf6d32
Autor:
Mohamed S. Benleulmi, Julien Matysiak, Xavier Robert, Csaba Miskey, Eric Mauro, Delphine Lapaillerie, Paul Lesbats, Stéphane Chaignepain, Daniel R. Henriquez, Christina Calmels, Oyindamola Oladosu, Eloïse Thierry, Oscar Leon, Marc Lavigne, Marie-Line Andreola, Olivier Delelis, Zoltán Ivics, Marc Ruff, Patrice Gouet, Vincent Parissi
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome. The data from the literature suggest that direct protein
Externí odkaz:
https://doaj.org/article/62671881f03f4030ac954009c672ddde
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56424 (2013)
The Feline Immunodeficiency Virus (FIV) capsid protein p24 oligomerizes to form a closed capsid that protects the viral genome. Because of its crucial role in the virion, FIV p24 is an interesting target for the development of therapeutic strategies,
Externí odkaz:
https://doaj.org/article/e2aa89ace57748369db0588f6338488d
Autor:
Allison Ballandras, Karen Moreau, Xavier Robert, Marie-Pierre Confort, Romain Merceron, Richard Haser, Corinne Ronfort, Patrice Gouet
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23032 (2011)
Integrase (IN) is an important therapeutic target in the search for anti-Human Immunodeficiency Virus (HIV) inhibitors. This enzyme is composed of three domains and is hard to crystallize in its full form. First structural results on IN were obtained
Externí odkaz:
https://doaj.org/article/ee7e78f9d1b346e9b2765106a6f6d12d
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1865(1)
Diffraction anisotropy is a phenomenon that impacts more specifically membrane proteins, compared to soluble ones, but the reasons for this discrepancy remained unclear. Often, it is referred to a difference in resolution limits between highest and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10864d736560add378aa0e6400ce726b
https://pubmed.ncbi.nlm.nih.gov/36206830
https://pubmed.ncbi.nlm.nih.gov/36206830
Diffraction anisotropy is a phenomenon that impacts more specifically membrane proteins, compared to soluble ones, but the reasons for this discrepancy remained unclear. Often, it is referred to a difference in resolution limits between highest and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36d53f54258bd8bf95aaf80fc92c665f
https://doi.org/10.1101/2021.12.07.471609
https://doi.org/10.1101/2021.12.07.471609
