Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Patrice Filée"'
Autor:
Charlotte Moens, Patrice Filée, Adrien Boes, Christian Alie, François Dufrasne, Emmanuel André, Sylvie Marché, David Fretin
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292590 (2023)
Serological assays for bovine tuberculosis diagnosis require the use of multiple Mycobacterium bovis specific antigens to ensure the detection of infected animals. In the present study, identification and selection process of antigens, based on data
Externí odkaz:
https://doaj.org/article/97820f4908d14381a71db8651874e5a4
Autor:
Mathieu Dondelinger, Patrice Filée, Eric Sauvage, Birgit Quinting, Serge Muyldermans, Moreno Galleni, Marylène S. Vandevenne
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Monoclonal antibodies are playing an increasing role in both human and animal health. Different strategies of protein and chemical engineering, including humanization techniques of non-human antibodies were applied successfully to optimize clinical p
Externí odkaz:
https://doaj.org/article/8196d446221b48d0b615208da71cfbfe
Use of an ALFexpress™ DNA Sequencer to Analyze Protein-Nucleic Acid Interactions by Band Shift Assay
Publikováno v:
BioTechniques, Vol 30, Iss 5, Pp 1044-1051 (2001)
Gel retardation analysis, or band shift assay, is technically the simplest method to investigate protein-nucleic acid interactions. In this report, we describe a nonradioactive band shift assay using a fluorescent DNA target and an ALFexpress™ auto
Externí odkaz:
https://doaj.org/article/477e43b23c144fbbb2b85402a7007513
Autor:
Natacha Scarafone, Coralie Pain, Anthony Fratamico, Gilles Gaspard, Nursel Yilmaz, Patrice Filée, Moreno Galleni, André Matagne, Mireille Dumoulin
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31253 (2012)
Nine neurodegenerative disorders, called polyglutamine (polyQ) diseases, are characterized by the formation of intranuclear amyloid-like aggregates by nine proteins containing a polyQ tract above a threshold length. These insoluble aggregates and/or
Externí odkaz:
https://doaj.org/article/3f7b315967bb4b17a7ea6dfedd289c44
Autor:
Charly Robert, Frédéric Kerff, Fabrice Bouillenne, Maxime Gavage, Marylène Vandevenne, Patrice Filée, André Matagne
Publikováno v:
Journal of Biological Chemistry. 299:102892
Autor:
Oscar Crasson, Patrice Filée, Mathieu Dondelinger, Marylène Vandevenne, Noureddine Rhazi, Régine Freischels, Moreno Galleni, Pierre Bogaerts, Sami Yunus, Astrid Freischels
Publikováno v:
Journal of Visualized Experiments.
Biosensors are becoming increasingly important and implemented in various fields such as pathogen detection, molecular diagnosis, environmental monitoring, and food safety control. In this context, we used β-lactamases as efficient reporter enzymes
Autor:
Olivier Jacquin, Astrid Freichels, Patrice Filée, Oscar Crasson, Noureddine Rhazi, Christine Jérôme, Moreno Galleni, Nadia Ruth, Marylène Vandevenne
Publikováno v:
Protein Engineering Design and Selection. 28:451-460
Antibody-based products constitute one of the most attractive biological molecules for diagnostic, medical imagery and therapeutic purposes with very few side effects. Their development has become a major priority of biotech and pharmaceutical indust
Autor:
Daniel Marechal, Yves Cenatiempo, Marylène Vandevenne, Gilles Gaspard, El Mustapha Belgsir, Jean-Marie Frère, Mireille Dumoulin, Manilduth Ramnath, Patrice Filée, André Matagne, Moreno Galleni
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1814:1146-1153
Irreversible accumulation of protein aggregates represents an important problem both in vivo and in vitro. The aggregation of proteins is of critical importance in a wide variety of biomedical situations, ranging from diseases (such as Alzheimer's an
Autor:
Alain Colige, Olivier Vanhooteghem, Nancy Garbacki, Agnès Noël, Patrice Filée, Abdel Aqil, Victor T. Tchemtchoua, Ganka Atanasova, Betty Nusgens, Christine Jérôme, Yves Poumay, Christophe Deroanne
Publikováno v:
Biomacromolecules. 12:3194-3204
The final goal of the present study was the development of a 3-D chitosan dressing that would shorten the healing time of skin wounds by stimulating migration, invasion, and proliferation of the relevant cutaneous resident cells. Three-dimensional ch
Autor:
Patrice Filée, Gilles Gaspard, Astrid Freichels, Moreno Galleni, Vincenzo Campisi, Jean-Marie Frère, Carole Gillard, Marylène Vandevenne
Publikováno v:
Protein Science. 20:1451-1463
This work analyses the chitin-binding and catalytic domains of the human macrophage chitotriosidase and investigates the physiological role of this glycoside hydrolase in a complex mechanism such as the innate immune system, especially its antifungal