Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Patrice Dumain"'
Publikováno v:
Cytometry. 39:195-202
BACKGROUND: Cell chemosensitivity to cytotoxic drugs has been attributed to their ability to trigger apoptosis. The emergence of resistance in drug-exposed cells is often characterized by the appearance of drug efflux mechanisms including P-gp transp
Autor:
Patrice Dumain, Josy Reiffers, P. Bernard, F. Durrieu, Francis Lacombe, M.R. Boisseau, F. Belloc, M.A. Belaud-Rotureau
Publikováno v:
Cytometry. 36:140-149
Background: Some forms of chemoresistance in leukemia may start from failure of tumour cells to successfully undergo apoptosis and Bcl-2 may play a role in this defect. Therefore, we evaluated the Bcl-2 content and synthesis in relation with the apop
Autor:
Patrice Dumain, C. Boyer, Jean-Michel Boiron, Josy Reiffers, S. Cotteret, Bilhou-Nabera C, Francis Belloc, Francis Lacombe, P. Bernard
Publikováno v:
Cytometry. 34:216-222
We studied the feasibility and the sensitivity of fluorescent in situ hybridization (FISH) using leukemic or host/donor-specific probes on flow-sorted cells to assess minimal residual disease (MRD) or chimerism in transplanted patients in complete re
Autor:
Francis Lacombe, Patrice Dumain, L. Lacoste, P. Bernard, Josy Reiffers, M.R. Boisseau, J. Dachary-Prigent, F. Durrieu, H. Morjani, F. Belloc, J. Chabrol
Publikováno v:
Experimental Cell Research. 240:165-175
An increasing number of methods are being described to detect apoptotic cells. However, attempts to detect apoptotic cells in clinical samples are rarely successful. A hypothesis is that apoptotic cells are cleared from the circulation by phagocytosi
Autor:
Francis Lacombe, F. Durrieu, F. Belloc, P. Bernard, A. Briais, M.R. Boisseau, Josy Reiffers, Patrice Dumain, E. Bascans
Publikováno v:
Leukemia. 11:1878-1886
A flow cytometry method has been introduced into the routine investigation of whole bone marrow samples following red blood cell lysis on the basis of a primary CD45/side scatter (SSC) gating procedure. Blast cells were first identified by CD45/SSC g
Autor:
Christèle Closse, Martine Renard, Patrice Dumain, Francis Belloc, Martine Seigneur, Annie Pruvost, Michel R. Boisseau
Publikováno v:
Thrombosis Research. 85:159-164
P-selectin is an endothelial adhesion molecule involved in the initial step of the neutrophil recruitment. We investigated the effect of hypoxia (95% N2, 5% CO2) and of hypoxia-reoxygenation (95% air, 5% CO2) on the expression of P-selectin by human
Autor:
I. Elalamy, Sanne Valentin, J.P. Vannier, Martine Renard, Theo Lindhout, C. Soria, Harlan F. Weisman, Bengt Zöller, A.M.H.P. van.den.Besselaar, A. Pruvost, M. Trossaërt, Kalid Azzam, Michel René Boisseau, J. Paysant, Désiré Collen, Andreas Hillarp, M. Martínez, Amparo Vaya, Amparo Vayá, A. Maurel, Barry S. Coller, Ferruccio Berti, Chiara Cerletti, Keaven M. Anderson, J. Conard, Ludovic Drouet, M. Renard, Annie Pruvost, Alexander G.G. Turpie, R.R. Forastiero, A. Del Maschio, Michel Bonneau, J. Dalmau, Francis Belloc, Irene Lluch, G. van Willigen, D. Simon, Helen Ireland, J.W.N. Akkerman, Giovannni de Gaetano, Irene Salemink, M. Verstraete, N. Resnick-Roguel, Reiner Muller-Peddinghaus, Claire Bal dit Sollier, Patrick Andre, Justo Aznar, Alan T. Nurden, M. Pick, M. Vasse, C. Closse, Margareta Hellgren, James H. Chesebro, Lorenzo Gil, Björn Dahlbäck, A. Panet, David A. Lane, Sophie Gandrille, L.O. Carreras, Marcial Martínez, Marie-Claire Boffa, Norma B de Bosch, G. Kunz, Yale Nemerson, M. Korner, M.H. Horellou, Per Morten Sandset, John T. Fallon, David Bergqvist, Rafael Carmena, Patrice Dumain, D. Sela-Donenfeld, M.R. Boisseau, Roberto Marti, Pier Mannuccio Mannucci, J.P. Collet, Angelo Sala, L. Poller, E. Dejana, M. Seigneur, Valentin Fuster, A. Zanetti, Frans Van de Werf, Douglas A. Triplett, Joan E.B. Fox, Armando Tripodi, Christèle Closse, Virgilio Evangelista, Martine Aiach, F. Belloc, M.M. Samama, Rafael Apitz, J. Soria, J. Hirsh, B. Boneu, Giancarlo Folco, Jacques Maclouf, Virgilio Bosch, George M. Willems, Peter Carmeliet, Patricia Hainaud, Giuseppe Rossoni, Konstantinos Kyriakoulis, M. Labios, Steven Vanderschueren, George Pignaud, A. Eldor, JuanJose Badimon, Martine Seigneur
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 26:I-VII
Autor:
Pascale Dufourcq, Martine Seigneur, Jean Amiral, Patrice Dumain, Annie Pruvost, Francis Belloc, Michel R. Boisseau
Publikováno v:
Thrombosis Research. 77:305-310
Thrombomodulin is a membrane glycoprotein expressed by endothelium and is a receptor for thrombin. The thrombin-thrombomodulin complex inactivates the procoagulant activity of thrombin and catalyzes activation of protein C(1). The decrease in thrombo
Autor:
Michel R. Boisseau, Francis Lacombe, Patrice Dumain, Francis Belloc, Claudine Jaloustre, Michèle Lenoble
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:S71-S74
Apoptosis or programmed cell death (PCD) was measured in two human cell models by flow cytometric analysis. Blood neutrophils underwent spontaneous apoptosis in short-term culture. Pentoxifylline (PTX) inhibited spontaneous neutrophil PCD. We confirm
Autor:
Josy Reiffers, Philippe Bernard, Francis Lacombe, M.R. Boisseau, Francis Belloc, Patrice Dumain, Claudine Jalloustre
Publikováno v:
Cytometry. 17:59-65
A flow cytometric method to detect apoptotic cells is described. This method is based on the detection of differences in chromatin condensation with Hoechst 33342 as a probe and the detection of dead cells with propidium iodide as a probe for membran