Vascular Signalling

Autor: Silvia Dragoni, Patric Turowski

Publikováno v: Cells, Vol 12, Iss 16, p 2038 (2023)

In all vertebrates, closed blood and open lymph circulatory systems are essential for the delivery of nutrients and oxygen to tissues, waste clearance, and immune function [...]

Externí odkaz: https://doaj.org/article/d2f0263582c64a3098e20d373af29662

CCL4 induces inflammatory signalling and barrier disruption in the neurovascular endothelium

Autor: Carolina Estevao, Chantelle E. Bowers, Ding Luo, Mosharraf Sarker, Alexandra Eva Hoeh, Karen Frudd, Patric Turowski, John Greenwood

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100370- (2021)

Background: During neuroinflammation many chemokines alter the function of the blood-brain barrier (BBB) that regulates the entry of macromolecules and immune cells into the brain. As the milieu of the brain is altered, biochemical and structural cha

Externí odkaz: https://doaj.org/article/92718fae1aa94d9686a1b71bfef83a9b

Endothelial Protease Activated Receptor 1 (PAR1) Signalling Is Required for Lymphocyte Transmigration across Brain Microvascular Endothelial Cells

Autor: Silvia Dragoni, Anna Papageorgiou, Caroline Araiz, John Greenwood, Patric Turowski

Publikováno v: Cells, Vol 9, Iss 12, p 2723 (2020)

Lymphocyte transendothelial migration (TEM) relies on ICAM-1 engagement on the luminal surface of the endothelial cells (ECs). In blood–brain barrier (BBB) ECs, ICAM-1 triggers TEM signalling, including through JNK MAP kinase and AMP-activated prot

Externí odkaz: https://doaj.org/article/ebccf60bb499407cbd0fa930d91295a8

Diagnostic circulating biomarkers to detect vision‐threatening diabetic retinopathy: Potential screening tool of the future?

Autor: Yeddula Rebecca Revathy, Karen Frudd, Subramanian Krishnakumar, Patric Turowski, Rajiv Raman, Sobha Sivaprasad

Publikováno v: Acta Ophthalmologica. 100

With the increasing prevalence of diabetes in developing and developed countries, the socio-economic burden of diabetic retinopathy (DR), the leading complication of diabetes, is growing. Diabetic retinopathy (DR) is currently one of the leading caus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6205ba7667131b095991e8c353122a91
https://doi.org/10.1111/aos.14954

Nanomedicine-based technologies and novel biomarkers for the diagnosis and treatment of Alzheimer's disease: from current to future challenges

Autor: Marta Marquié, Miren Ettcheto, Maria Luisa García, Mercè Boada, Agustín Ruiz, Giovanni Tosi, Jason T. Duskey, Amanda Cano, Patric Turowski, Elena Sánchez-López, Eliana B. Souto, Antonio Camins

Publikováno v: Journal of Nanobiotechnology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-30 (2021)

Increasing life expectancy has led to an aging population, which has consequently increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of dementia worldwide, is estimated to make up 50--80% of all cases. AD cases are e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957228af9eace124e31fcfac95c02061
https://pubmed.ncbi.nlm.nih.gov/33926475