Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Patric M. Schiltz"'
Autor:
Andrew N. Cornforth, Robert O. Dillman, Patric M. Schiltz, Senthamil R. Selvan, Carol DePriest, Gary B. Fogel
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 26:407-415
Previously, a 54% 5-year survival was reported for metastatic melanoma patients treated with patient-specific vaccines consisting of autologous dendritic cells loaded with antigens from autologous proliferating tumor cells. This study attempted to de
Publikováno v:
Journal of Equine Veterinary Science. 31:78-84
Although there has been a recent surge in using horses to treat mental and emotional human health issues, the consequences of horse-assisted interventions on the stress response of horses have not been well documented. Assessment of the autonomic ner
Publikováno v:
Journal of Bone and Mineral Research. 8:391-396
This laboratory has purified a unique insulin-like growth factor binding protein (IGFBP-4) that was previously demonstrated to be inhibitory to bone cell proliferation. In this study, the hypothesis that IGFBP-4 is inhibitory to insulin-like growth f
Autor:
Andrew N. Cornforth, Madeline Carol DePriest, Robin Anne Ellis, Shari Lynn Sharp, Robert O. Dillman, Patric M. Schiltz, Christopher Duma
Publikováno v:
Journal of Immunotherapy. 32:914-919
Despite recent advances, median survival for patients with resectable glioblastoma multiforme (GBM) is only 12 to 15 months. We previously observed minimal toxicity and a 9.0-month median survival after treatment with intralesional autologous lymphok
Autor:
Neil Hoa, H. Terry Wepsic, Christina Delgado, Gerald Vandeusen, Patric M. Schiltz, Martin R. Jadus, Michael P. Myers, Linda L. Callahan, Jian Gang Zhang
Publikováno v:
Laboratory Investigation. 87:115-129
In this study, human monocytes/macrophages were observed to kill human U251 glioma cells expressing membrane macrophage colony-stimulating factor (mM-CSF) via a swelling and vacuolization process called paraptosis. Human monocytes responded to the mM
Autor:
Robert O. Dillman, Linda D. Beutel, Shankar K. Nayak, Carol DePriest, Senthamil R. Selvan, Patric M. Schiltz
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 20:373-378
Determination of potency is a challenging problem for patient-specific products derived from autologous cells. For several years, we have been investigating the safety and therapeutic potential of patient- specific vaccines derived from short-term au
Autor:
David T. Price, Robert O. Dillman, Andrew N. Cornforth, Ray P. Liao, F. Scott Heinemann, Patric M. Schiltz, Nagesh Rao, Senthamil R. Selvan, Yvonne Reid
Publikováno v:
The Prostate. 63:91-103
BACKGROUND Development of new therapeutic modalities for human prostate carcinoma has been impeded by a lack of adequate in vitro and in vivo models. Most in vitro studies have been carried out using a limited number of human prostate cancer cell lin
Autor:
Robert O. Dillman, Neil M. Barth, Linda D. Beutel, Senthamil R. Selvan, Cheryl Peterson, Edward F. McClay, Patric M. Schiltz, Patric Sheehy, Cristina de Leon, Kanoe Allen, Carol DePriest
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 19:658-665
The aim of this study was to investigate the feasibility, safety, and clinical efficacy of patient-specific dendritic cell vaccines in patients with metastatic melanoma. A planned interim analysis was conducted on the first 20 patients.Tumor cell lin
Autor:
Robert O. Dillman, Patric M. Schiltz
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 18:879-886
Short-term autologous tumor vaccines were established and used to treat metastatic melanoma patients. Serum samples obtained prior to (week 0) and after three vaccinations (week 4) were assayed for interleukin (IL)-2, interferon (IFN)-gamma, IL-4, an
Publikováno v:
Cancer Research. 77:4159-4159
Assessing IVDR to Chemo and BM expression in tumors of patients (Pts) before treatment can stratify therapy and improve outcome. Historical IVDR and BM data were analyzed retrospectively on 582 human LC specimens including 311 adenocarcinomas (ADCA),