Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Patrícia de A. Machado"'
Autor:
Patrícia de A. Machado, Pollyanna S. Gomes, Monique P. D. Carneiro, Victor Midlej, Elaine S. Coimbra, Herbert L. de Matos Guedes
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1373 (2022)
Studies have previously demonstrated the importance of serine proteases in Leishmania. A well-known serine protease inhibitor, TPCK, was used in the present study to evaluate its in vitro and in vivo antileishmanial effects and determine its mechanis
Externí odkaz:
https://doaj.org/article/0557302ecb934fa391ea53ea15cf1b74
Autor:
Pollyanna Stephanie Gomes, Monique Pacheco Duarte Carneiro, Patrícia de Almeida Machado, Valter Viana de Andrade-Neto, Alessandra Marcia da Fonseca-Martins, Amy Goundry, João Vitor Marques Pereira da Silva, Daniel Claudio Oliveira Gomes, Ana Paula Cabral de Araujo Lima, Vítor Ennes-Vidal, Ana Carolina Rennó Sodero, Salvatore Giovanni De-Simone, Herbert L. de Matos Guedes
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 5, Pp 2089-2106 (2022)
Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In Leishmania major and L. donovani, this enzyme has been described as essential to their survival; however, few compounds that
Externí odkaz:
https://doaj.org/article/14a0437ab2f54905977ef75da53f1211
Autor:
Naira Moura Alves, Vanessa de Sousa Cruz, Leandro Lopes Nepomuceno, Nayane Peixoto Soares, Emmanuel Arnhold, Daniel Graziani, Patrícia de Almeida Machado Gonçalves, Guilherme Henrique Salazar Badan, Amanda da Matta Santos, Eugênio Gonçalves de Araújo
Publikováno v:
Ciência Animal Brasileira, Vol 23 (2022)
A Curcuma longa L., planta conhecida popularmente como açafrão, tem sido amplamente estudada por suas diversas propriedades terapêuticas, incluindo a ação antineoplásica. O extrato etanólico da planta contém diversos compostos fenólicos, com
Externí odkaz:
https://doaj.org/article/30f9d3df3cdc44a2ac74a25f94a70aa3
Autor:
Priscila Porrua, Daniele Cristina da Silva Kazama, Cristine Garcia Gabriel, Gabriele Rockenbach, Maria Cristina Marino Calvo, Patrícia de Oliveira Machado, Janaina das Neves, Ruan Weiss
Publikováno v:
Cadernos de Saúde Coletiva, Vol 28, Iss 3, Pp 426-437 (2020)
Resumo Introdução A compra institucional para a alimentação escolar é uma oportunidade de incentivo a novas cadeias de abastecimento, sobretudo em nível local. Objetivo Avaliar a gestão municipal do Programa Nacional de Alimentação Escolar (
Externí odkaz:
https://doaj.org/article/ba29e348e6f840e490965c3cf22a25eb
Autor:
Patrícia de Almeida Machado Gonçalves, Vanessa de Souza Cruz, Leandro Lopes Nepomuceno, Nayane Peixoto Soares, Karla Márcia da Silva Braga, Naira Moura Alves, Emmanuel Arnhold, Eugênio Gonçalves de Araújo
Publikováno v:
Acta Scientiarum: Biological Sciences, Vol 43, Iss 1 (2021)
The selective activity of an antineoplastic drug is related to its ability to promote cytotoxic action on tumor cells and preserve the integrity of non-neoplastic cells. Beta-lapachone is extracted from the sawdust of Ipe wood, a thick bark tree from
Externí odkaz:
https://doaj.org/article/13c7482f596d4c579e33de4411193b2b
Autor:
Patrícia de Almeida Machado, Pollyanna Stephanie Gomes, Victor Midlej, Elaine Soares Coimbra, Herbert Leonel de Matos Guedes
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
PF-429242 is an inhibitor of subtilisin, an important protease found in Leishmania. However, studies regarding the effect of PF-429242 on Leishmania are scarce. In this work we evaluated the antileishmanial effect of PF-429242 against Leishmania infa
Externí odkaz:
https://doaj.org/article/965d7a086f1247e0b95f01d578a7c4cc
Publikováno v:
Ciência Brasileira: Múltiplos olhares-Administração, Contabilidade, Economia e Gestão ISBN: 9788557225664
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0119d0db0a9c152fd4834d64cec031d3
https://doi.org/10.29327/cb-administracao-contabilidade-economia-e-gestao-1.598850
https://doi.org/10.29327/cb-administracao-contabilidade-economia-e-gestao-1.598850
Publikováno v:
Anais do I Congresso Brasileiro On-line Multiprofissional de Análises Clínicas e Laboratoriais.
Introdução: Leishmania é um protozoário intracelular obrigatório que reside em macrófagos do hospedeiro mamífero. Cerca de 20 espécies de Leishmania são capazes de infectar o ser humano, causando as leishmanioses, que podem se apresentar em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ceabd76ce81f32fbb6d4357f4ef476
https://doi.org/10.51161/conalab/8465
https://doi.org/10.51161/conalab/8465
Autor:
Luciana Ramos Gaston Brandstetter, Eugênio Gonçalves de Araújo, Juan Carlos Duque Moreno, Maria Clorinda Soares Fioravanti, Veridiana Maria Brianezi Dignani de Moura, Patrícia de Almeida Machado
Publikováno v:
Ciência Rural, Vol 44, Iss 1, Pp 85-91 (2014)
The effects of topical and intraluminal Carolina Rinse Solution (CRS) in p44/42 (ERK 1/2) and p38 MAPK activation profile, in rabbit jejunum after ischemia and reperfusion (I/R), were investigated in this study. Fifteen New Zealand rabbits were alloc
Externí odkaz:
https://doaj.org/article/dbfd42ad1301474fb04b694aa5cc7aa1
Autor:
Luciana Ramos Gaston Brandstetter, Eugênio Gonçalves de Araújo, Juan Carlos Duque Moreno, Maria Clorinda Soares Fioravanti, Veridiana Maria Brianezi Dignani de Moura, Patrícia de Almeida Machado
Publikováno v:
Ciência Rural, Vol 44, Iss 1, Pp 85-91 (2013)
The effects of topical and intraluminal Carolina Rinse Solution (CRS) in p44/42 (ERK 1/2) and p38 MAPK activation profile, in rabbit jejunum after ischemia and reperfusion (I/R), were investigated in this study. Fifteen New Zealand rabbits were alloc
Externí odkaz:
https://doaj.org/article/72c5c6a3d07a46dd855e0c0103cfe030