Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Patrícia S. Brocardo"'
Publikováno v:
Brain Sciences, Vol 13, Iss 12, p 1610 (2023)
Neuroplasticity refers to the ability of the brain to reorganize and modify its neural connections in response to environmental stimuli, experience, learning, injury, and disease processes. It encompasses a range of mechanisms, including changes in s
Externí odkaz:
https://doaj.org/article/a2b91450f0e3460a80fe5ae7b79251cd
Publikováno v:
IBRO Neuroscience Reports, Vol 12, Iss , Pp 203-209 (2022)
Small ubiquitin-like modifiers, SUMOs, are proteins that are conjugated to target substrates and regulate their functions in a post-translational modification called SUMOylation. In addition to its physiological roles, SUMOylation has been implicated
Externí odkaz:
https://doaj.org/article/f17ad99440154a7aae528207b23fc7ea
Autor:
Evelini Plácido, Priscilla Gomes Welter, Ana Wink, Gabriela Duarte Karasiak, Tiago Fleming Outeiro, Alcir Luiz Dafre, Joana Gil-Mohapel, Patricia S. Brocardo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12607 (2023)
Huntington’s disease (HD) is a neurodegenerative genetic disorder characterized by motor, psychiatric, cognitive, and peripheral symptoms without effective therapy. Evidence suggests that lifestyle factors can modulate disease onset and progression
Externí odkaz:
https://doaj.org/article/de59c4f271364e63ab9fead3a2ce6624
Autor:
Patrícia S, Brocardo, Josiane, Budni, Eloísa, Pavesi, Jeferson L, Franco, Marcela, Uliano-Silva, Rafael, Trevisan, Mariana G, Terenzi, Alcir L, Dafre, Ana Lúcia S, Rodrigues
Publikováno v:
Bipolar disorders. 12(4)
Bipolar disorder (BD) is a chronic, prevalent, and highly debilitating psychiatric illness. Folic acid has been shown to have antidepressant-like effects in preclinical and clinical studies and has also been suggested to play a role in BD. The presen
Autor:
Daiane F. Engel, Anna N. Grzyb, Jade de Oliveira, Alexandra Pötzsch, Tara L. Walker, Patricia S. Brocardo, Gerd Kempermann, Andreza F. de Bem
Publikováno v:
Molecular Metabolism, Vol 30, Iss , Pp 1-15 (2019)
Objective: In familial hypercholesterolemia (FH), mutations in the low-density lipoprotein (LDL) receptor (LDLr) gene result in increased plasma LDL cholesterol. Clinical and preclinical studies have revealed an association between FH and hippocampus
Externí odkaz:
https://doaj.org/article/00a2c25fde98404a98b9738f48971ca1
Autor:
Cristine de Paula Nascimento-Castro, Elisa C. Winkelmann-Duarte, Gianni Mancini, Priscilla Gomes Welter, Evelini Plácido, Marcelo Farina, Joana Gil-Mohapel, Ana Lúcia S. Rodrigues, Andreza Fabro de Bem, Patricia S. Brocardo
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1433 (2022)
Huntington’s disease (HD) is a genetic neurodegenerative disease characterized by motor, psychiatric, and cognitive symptoms. Emerging evidence suggests that emotional and cognitive deficits seen in HD may be related to hippocampal dysfunction. We
Externí odkaz:
https://doaj.org/article/f76cc44072f5426a9693e92fe72a028b
Publikováno v:
Brain Sciences, Vol 11, Iss 9, p 1250 (2021)
Binge alcohol consumption and alcohol use disorders (AUD) are prevalent, and there is comorbidity with depression and anxiety. Potential underlying mechanisms include neurophysiological, genetic, and metabolic changes resulting from alcohol exposure.
Externí odkaz:
https://doaj.org/article/3346aa6019c3408f9bbb224f038a59fe
Autor:
Amy Kim, Kathryn Lalonde, Aaron Truesdell, Priscilla Gomes Welter, Patricia S. Brocardo, Tatiana R. Rosenstock, Joana Gil-Mohapel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8363 (2021)
Huntington’s disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum and cortex. The first symptoms usually appear in mid-life and includ
Externí odkaz:
https://doaj.org/article/e3e3eeb5e0c7404fa3ddc5eb11137b32
Autor:
Thayza Martins Melzer, Luana Meller Manosso, Suk-yu Yau, Joana Gil-Mohapel, Patricia S. Brocardo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 5026 (2021)
Consuming a balanced, nutritious diet is important for maintaining health, especially as individuals age. Several studies suggest that consuming a diet rich in antioxidants and anti-inflammatory components such as those found in fruits, nuts, vegetab
Externí odkaz:
https://doaj.org/article/9af9a289aeb24e8bbd4369a239af8fd4
Autor:
Flavia Carla Meotti, Juliana Martins Rosa, Patrícia S. Brocardo, Daniela Balz, Ana Paula Waltrick, Angelize Bagio, Eduardo Comeli Goulart, Alcir Luiz Dafre, Ana Lúcia S. Rodrigues, Adair R. S. Santos
Publikováno v:
Journal of Pharmacy & Pharmacology; Jan2006, Vol. 58 Issue 1, p137-142, 6p