Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Patrícia Machado Rodrigues e Silva"'
Autor:
Leda Castaño Barrios, Ana Paula Da Silva Pinheiro, Daniel Gibaldi, Andrea Alice Silva, Patrícia Machado Rodrigues E Silva, Ester Roffê, Helton da Costa Santiago, Ricardo Tostes Gazzinelli, José Roberto Mineo, Neide Maria Silva, Joseli Lannes-Vieira
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258199 (2021)
The Apicomplexa protozoan Toxoplasma gondii is a mandatory intracellular parasite and the causative agent of toxoplasmosis. This illness is of medical importance due to its high prevalence worldwide and may cause neurological alterations in immunocom
Externí odkaz:
https://doaj.org/article/45f4dafd306343b8a87a66fcfa95dd2e
Autor:
Tatiana Paula Teixeira Ferreira, Januário Gomes Mourão e Lima, Francisco Alves Farias-Filho, Yago Amigo Pinho Jannini de Sá, Ana Carolina Santos de Arantes, Fernanda Verdini Guimarães, Vinicius de Frias Carvalho, Cory Hogaboam, John Wallace, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Silicosis is an occupational disease triggered by the inhalation of fine particles of crystalline silica and characterized by inflammation and scarring in the form of nodular lesions in the lungs. In spite of the therapeutic arsenal currently availab
Externí odkaz:
https://doaj.org/article/79323c491b6b427b873f736c1cd2efd8
Autor:
Tatiana Paula Teixeira Ferreira, Fernanda Verdini Guimarães, Yago Amigo Pinho Jannini Sá, Natalia Barreto da Silva Ribeiro, Ana Carolina Santos de Arantes, Vinicius de Frias Carvalho, Lirlândia Pires Sousa, Mauro Perretti, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva
Publikováno v:
Cells, Vol 11, Iss 5, p 759 (2022)
Annexin-A1 (AnxA1) and its N-terminal derived peptide Ac2-26 regulate the inflammatory response in several experimental models of disorders. This study evaluated the effect of endogenous AnxA1 and its N-terminal peptide Acetyl 2-26 (Ac2-26) on allerg
Externí odkaz:
https://doaj.org/article/e86f48facffc40a6ae52e7941fdf0630
Autor:
Maximiliano Ruben Ferrero, Cristiana Couto Garcia, Marcella Dutra de Almeida, Jullian Torres Braz da Silva, Daniella Bianchi Reis Insuela, Tatiana Paula Teixeira Ferreira, Diego de Sá Coutinho, Carolina Trindade de Azevedo, Patrícia Machado Rodrigues e Silva, Marco Aurélio Martins
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 620 (2021)
Influenza A virus (IAV) infection is a common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Since macrophage inflammatory protein 1 α, a chemokine that acts through CC-chemokine receptor (CCR)-5, appears elevated in
Externí odkaz:
https://doaj.org/article/fb62868389d3435fbeec5a05d437e7f0
Autor:
Maria Talita Pacheco de Oliveira, Diego de Sá Coutinho, Sílvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Patrícia Machado Rodrigues e Silva, Marco Aurélio Martins, Andressa Bernardi
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 683 (2021)
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are inflammatory and oxidative imbalance lung conditions with no successful pharmacological therapy and a high mortality rate. Resveratrol (RSV) is a plant-derived stilbene that p
Externí odkaz:
https://doaj.org/article/9a7e4520c5e24e97b6ac8c27e09a586b
Autor:
Diego de Sá Coutinho, Jader Pires, Hyago Gomes, Adriana Raffin Pohlmann, Sílvia Stanisçuaski Guterres, Patrícia Machado Rodrigues e Silva, Marco Aurelio Martins, Stela Regina Ferrarini, Andressa Bernardi
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1075 (2020)
Pequi is a Brazilian fruit used in folk medicine for pulmonary diseases treatment, but its oil presents bioavailability limitations. The use of nanocarriers can overcome this limitation. We developed nanoemulsions containing pequi oil (pequi-NE) and
Externí odkaz:
https://doaj.org/article/e1a47a6d1e184cd685d8c891c756a8fc
Autor:
Lídia Moreira Lima, Eliezer J. Barreiro, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva, Thiago José Figueira Ramos, Ana Carolina Santos de Arantes, Maria Letícia de Castro Barbosa
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14651-14672 (2012)
In this paper we report the design, synthesis and pharmacological evaluation of a new series of phenyl sulfonamide derivatives 2a–h and 3–8 planned by structural modification on the anti-inflammatory prototype LASSBio-468 (1). Among the synthesiz
Externí odkaz:
https://doaj.org/article/8b16ce12ee7a4efe8c6700c3b4a3a081
Autor:
Isabelle Karine da Costa Nunes, Everton Tenório de Souza, Suzana Vanessa S Cardozo, Vinicius de Frias Carvalho, Nelilma Correia Romeiro, Patrícia Machado Rodrigues E Silva, Marco Aurélio Martins, Eliezer J Barreiro, Lídia Moreira Lima
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0162895 (2016)
Prior investigations showed that increased levels of cyclic AMP down-regulate lung inflammatory changes, stimulating the interest in phosphodiesterase (PDE)4 as therapeutic target. Here, we described the synthesis, pharmacological profile and docking
Externí odkaz:
https://doaj.org/article/bb6839c98cab430e96802150d53509a7
Autor:
Amanda da Silva, Chaves, Nathalia Santos, Magalhães, Daniella Bianchi Reis, Insuela, Patrícia Machado Rodrigues E, Silva, Marco Aurélio, Martins, Vinicius Frias, Carvalho
Publikováno v:
Frontiers in Endocrinology. 13
Prior investigation shows an increase in the activity of both hypothalamus-pituitary-adrenal (HPA) axis and the renin-angiotensin system (RAS) in diabetic patients. Moreover, activation of angiotensin-II type 1 receptor (AT1) has been associated with
Autor:
Tatiana Paula Teixeira Ferreira, Fernanda Verdini Guimarães, Yago Amigo Pinho Jannini Sá, Natalia Barreto da Silva Ribeiro, Ana Carolina Santos de Arantes, Vinicius de Frias Carvalho, Lirlândia Pires Sousa, Mauro Perretti, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva
Publikováno v:
Cells; Volume 11; Issue 5; Pages: 759
Annexin-A1 (AnxA1) and its N-terminal derived peptide Ac2-26 regulate the inflammatory response in several experimental models of disorders. This study evaluated the effect of endogenous AnxA1 and its N-terminal peptide Acetyl 2-26 (Ac2-26) on allerg